{"id":3724,"date":"2019-06-08T14:01:52","date_gmt":"2019-06-08T05:01:52","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=3724"},"modified":"2019-06-08T14:01:52","modified_gmt":"2019-06-08T05:01:52","slug":"how-to-bring-preprints-to-the-charged-field-of-medicine","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3724","title":{"rendered":"How to bring preprints to the charged field of medicine"},"content":{"rendered":"

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MedRxiv launches with beefed up screening processes to allay concerns about risks of publishing unvetted clinical research.<\/h5>\n

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The founders of the\u00a0popular biology preprint server bioRxiv<\/a>\u00a0have launched a repository on which medical scientists can share their results before peer review.<\/p>\n

BioRxiv\u2019s success<\/a>\u00a0prompted some clinical scientists to push for such a site because the biology repository accepts preprints in only certain fields of medical science. But some researchers are concerned that releasing unvetted clinical research could be risky, if patients or doctors act on what could end up being inaccurate information.<\/p>\n

The organizations behind the new server, named medRxiv, have been working on the project since 2017 and say they have built in safeguards to address those concerns.<\/p>\n

They will require authors to provide details of ethical approvals for their studies and consent from patients, and to disclose all funding sources. Preprints will be screened by an external clinical scientist and an experienced clinical editor supported by the developing organizations \u2014 Cold Spring Harbour Laboratory in New York, the publisher BMJ in London and Yale University in New Haven, Connecticut.<\/p>\n

If screening generates a concern, the paper will be escalated to a clinical editor and a final decision could be made by medRxiv\u2019s six-person management team, says John Inglis, executive director of Cold Spring Harbor Laboratory Press and co-founder of medRxiv and bioRxiv, which\u00a0launched in 2013<\/a>.<\/p>\n

And the medRxiv team says it won\u2019t post research deemed a risk to the public \u2014 for instance, new information about a drug\u2019s side effects that could encourage patients to stop taking life-saving medication without medical advice. The website and individual preprints will also say clearly that the work is not peer reviewed and shouldn\u2019t be used to guide treatment or be reported in the press as a medical advance. The medRxiv site will be live on 25 June but\u00a0is now accepting manuscripts<\/a>.<\/p>\n

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Fast exchange<\/strong><\/p>\n

Proponents of preprints<\/a>\u00a0say that posting manuscripts online before the lengthy peer-review process required by conventional journals speeds up scientific discovery. Researchers can receive feedback or communicate negative findings, which journals might be reluctant to publish. Physicists and mathematicians\u00a0pioneered online preprints nearly 30 years ago<\/a>, and the past few years have seen a proliferation of servers for specific disciplines and\u00a0geographic<\/a>\u00a0regions<\/a>.<\/p>\n

But medical science is inherently different from other disciplines, which don\u2019t tend to see societal fall out from posting work before review, says David Maslove, a clinician-scientist at the Kingston General Health Research Institute in Canada. \u201cThere may be more public interest in medical studies and people may be more motivated to seek out and act on new information about treatment for certain diseases,\u201d he says. Maslove is encouraged by medRxiv\u2019s checks, but says that these are simply \u201cpeer review by another name\u201d.<\/p>\n

Marc Lipsitch, an epidemiologist at Harvard University in BostonCambridge, Massachusetts, says the experiment is worthy: during outbreaks of diseases such as Ebola or Zika, for instance, the fast and free exchange of information is important to scientists and clinicians.<\/p>\n

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(\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n

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    MedRxiv launches with beefed up screening processes to allay concerns about risks of publishing unvetted clinical research.     The founders of the\u00a0popular(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[33,35,29,30],"tags":[],"class_list":["post-3724","post","type-post","status-publish","format-standard","hentry","category-do-biology","category-lets-do-computer-science","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":1313,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1313","url_meta":{"origin":3724,"position":0},"title":"Did CRISPR really fix a genetic mutation in these human embryos?","author":"biochemistry","date":"August 9, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 Researchers provide more evidence for their landmark claim that gene editing rid embryos of a disease mutation \u2014 but scientists are still arguing over the results. \u00a0 \u00a0 Eight-cell embryos injected with the gene editor CRISPR\u2013Cas9.Credit: H. 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