![\"\"](\"https:\/\/imgnews.pstatic.net\/image\/081\/2019\/06\/04\/0003004159_001_20190604165110894.jpg?type=w647\")
<\/span><\/p>\n\u7f8e \uc5f0\uad6c\uc9c4, \u2018\uc80a\uc740 \ud53c\u2019 \uc18d \ub1cc \ub178\ud654 \ub418\ub3cc\ub9ac\ub294 \ub450 \uac00\uc9c0 \uc131\ubd84 \ubc1c\uacac(\uc0ac\uc9c4=123rf<\/span>)<\/em><\/span><\/p>\n <\/p>\n <\/p>\n \ubbf8\uad6d\uc758 \uacfc\ud559\uc790\ub4e4\uc774 \uc0c8\ub85c\uc6b4 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc80a\uc740 \uc950\uc758 \ud608\uc561 \uc18d\uc5d0\uc11c \ub1cc\uc758 \ub178\ud654 \uacfc\uc815\uc744 \ub418\ub3cc\ub9ac\ub294 \ub450 \uac00\uc9c0 \uc131\ubd84\uc744 \ud655\uc778\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n \ub274\uc0ac\uc774\uc5b8\ud2f0\uc2a4\ud2b8 \ub4f1 \uc678\uc2e0\uc5d0 \ub530\ub974\uba74, \ubbf8\uad6d \uc2a4\ud0e0\ud37c\ub4dc\ub300 \ubd84\uc790\u00b7\uc138\ud3ec\uc0dd\ub9ac\ud559 \uc5f0\uad6c\uc9c4\uc774 \uc5f0\uad6c\uc5d0\uc11c \uc0dd\ud6c4 12~15\uac1c\uc6d4 \ub41c \ub098\uc774 \ub4e0 \uc950\uc5d0\uac8c \uc0dd\ud6c4 2\uc8fc \ub41c \uc80a\uc740 \uc950\uc758 \ud608\uc561\uc744 \uc8fc\uc785\ud558\uba74 \ub1cc\uc758 \uae30\uc5b5\ub825\uacfc \ud559\uc2b5\ub2a5\ub825 \ub4f1\uc774 \uac10\ud1f4\ud558\ub294 \ub178\ud654 \uc99d\uc0c1\uc744 \ub418\ub3cc\ub9b4 \uc218 \uc788\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\ub2e4.<\/p>\n \uc774\ub294 \uc80a\uc740 \uc950\uc758 \ud608\uc561 \uc18d\uc5d0 \uc788\ub294 \ub450 \ub2e8\ubc31\uc9c8\uc774 \ub098\uc774 \ub4e0 \uc950\uc758 \ub1cc \uc2e0\uacbd\uc138\ud3ec\uc778 \u2018\ub274\ub7f0\u2019\uc758 \uc131\uc7a5\uc744 \ucd09\uc9c4\ud558\uace0 \uc774\ub4e4 \ub274\ub7f0 \uc0ac\uc774\uc758 \uc2e0\uacbd \uc5f0\uacb0\uc778 \u2018\uc2dc\ub0c5\uc2a4\u2019 \uc218\ub97c \ub298\ub9b0 \uac83\uc774\ub77c\uace0 \uc5f0\uad6c\uc9c4\uc740 \uc124\uba85\ud588\ub2e4.<\/p>\n \ub610 \uc5f0\uad6c\uc9c4\uc740 \ub450 \ub2e8\ubc31\uc9c8\uc744 \uc2e4\ud5d8\uc2e4\uc5d0\uc11c \ubc30\uc591\ud55c \uc0ac\ub78c\uc758 \ub274\ub7f0\uc5d0\ub3c4 \uc791\uc6a9\ud558\ub294\uc9c0 \uac80\uc0ac\ud588\uc73c\uba70 \ubc30\uc591\ub41c \ub274\ub7f0\uc758 \uc131\uc7a5\uc744 \ucd09\uc9c4\ud558\uace0 \uc2dc\ub0c5\uc2a4 \uc218\ub97c \ub298\ub9ac\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc8fc\ub294 \ub4f1 \ube44\uc2b7\ud55c \ud6a8\uacfc\ub97c \ud655\uc778\ud588\ub2e4.<\/p>\n \uc774\ub7f0 \uacb0\uacfc\ub294 \uc55e\uc73c\ub85c \ud68c\ucd98 \ubb18\uc57d\ubfd0\ub9cc \uc544\ub2c8\ub77c \ub178\ud654\ub85c \uc778\ud574 \ubc1c\uc0dd\ud558\ub294 \uce58\ub9e4\uc758 \uc601\ud5a5\uc744 \ub418\ub3cc\ub9ac\ub294 \uce58\ub8cc \ubc29\ubc95\uc744 \uac1c\ubc1c\ud558\ub294 \ub370\ub3c4 \ub3c4\uc6c0\uc774 \ub418\ub9ac\ub77c\ub294 \ud76c\ub9dd\uc744 \ubd88\ub7ec\uc77c\uc73c\ud0a8\ub2e4.<\/p>\n \uc5f0\uad6c\uc9c4\uc5d0 \ub530\ub974\uba74, \ud68c\ucd98 \ud6a8\uacfc\uac00 \uc788\ub294 \ub450 \uac00\uc9c0 \ud575\uc2ec \ub2e8\ubc31\uc9c8\uc740 \u2018\ud2b8\ub86c\ubcf4\uc2a4\ud3f0\ub518-4\u2019(THBS<\/span>4)\uc640 \u2018SPARC<\/span>\u00a0\uc720\uc0ac \ub2e8\ubc31\uc9c8 1\u2019(SPARCL<\/span>1)\uc73c\ub85c \ud655\uc778\ub410\ub2e4.<\/p>\n <\/p>\n \uc5f0\uad6c\ub17c\ubb38\uc5d0 \uc2e4\ub9b0 \uc774\ubbf8\uc9c0 \uc790\ub8cc.(\uc0ac\uc9c4=PNAS<\/span>)<\/em><\/span><\/p>\n <\/p>\n <\/p>\n \ubbf8\uad6d \uad6d\ub9bd\uacfc\ud559\uc6d0\ud68c\ubcf4(PNAS<\/span>) 3\uc77c\uc790\uc5d0 \uc2e4\ub9b0 \uc774\ubc88 \uc5f0\uad6c\ub17c\ubb38\uc5d0\uc11c \uc5f0\uad6c\uc9c4\uc740 \ub450 \ud654\ud569\ubb3c\uc774 \uc2dc\ub0c5\uc2a4 \uc218\ub97c \ub298\ub9b0\ub2e4\uace0 \uc37c\ub2e4.<\/p>\n \uac74\uac15\ud55c \ub1cc\uc5d0\uc11c\ub294 \uc0c8\ub85c\uc6b4 \uc2dc\ub0c5\uc2a4\uc758 \uc0dd\uc131\uacfc \uc624\ub798\ub41c \uc2dc\ub0c5\uc2a4\uc758 \uc190\uc2e4\uc774 \uade0\ud615\uc744 \uc774\ub8e8\uc9c0\ub9cc, \uc774\ub7f0 \uacfc\uc815\uc740 \ub098\uc774\uac00 \ub4e4\uc218\ub85d \ub290\ub824\uc838 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uacfc \uac19\uc740 \uce58\ub9e4\ub97c \uc77c\uc73c\ud0a4\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc84c\ub2e4. \uc2dc\ub0c5\uc2a4\uc758 \uc190\uc2e4\uc774 \ubb34\uc5b8\uac00\ub97c \uae30\uc5b5\ud558\uae30 \uc5b4\ub835\uac8c \ub9cc\ub4e4\uae30 \ub54c\ubb38\uc774\ub2e4.<\/p>\n \uc5f0\uad6c\ub17c\ubb38 \uc8fc\uc800\uc790\uc778 \uce90\uc2a4\ub9b0 \uac04 \ubc15\uc0ac\ud6c4\uc5f0\uad6c\uc6d0\uacfc \uacf5\ub3d9\uc800\uc790\uc778 \ud1a0\ub9c8\uc2a4 \uc950\ud2b8\ud638\ud504 \ubc15\uc0ac\ub294 \u201c\uc6b0\ub9ac\ub294 \uc80a\uc740 \uc950\uc758 \ud53c\uac00 \uc2dc\ub0c5\uc2a4 \ud615\uc131\uc744 \ucd09\uc9c4\ud558\uae30 \uc704\ud574 \ub274\ub7f0\uc5d0 \uc9c1\uc811 \uc791\uc6a9\ud558\ub294 \uc694\uc778\uc744 \uac15\ud654\ud558\ub294\uc9c0\uc5d0 \uc758\ubb38\uc744 \uac00\uc84c\ub2e4. \uc6b0\ub9ac\ub294 \uc80a\uc9c0\ub9cc \ub299\uc9c0 \uc54a\uc740 \uc950\uc758 \ud608\uccad\uc774 \ubc30\uc591\ub41c \ub274\ub7f0 \uc0ac\uc774\uc5d0 \uc2dc\ub0c5\uc2a4 \ud615\uc131\uc744 \uc2e4\uc81c\ub85c \uc9c1\uc811 \ucd09\uc9c4\ud558\ub294 \uac83\uc744 \ubcf4\uc5ec\uc92c\uc73c\uba70 \uc5b4\ub9b0 \uc950\uc758 \ud608\uc561\uc5d0\uc11c \u2018\ud2b8\ub86c\ubcf4\uc2a4\ud3f0\ub518-4\u2019\uc640 \u2018SPARC<\/span>\u00a0\uc720\uc0ac \ub2e8\ubc31\uc9c8 1\u2019\uc774\ub77c\ub294 \ub450 \uc694\uc778\uc758 \uac15\ud654\uc640 \uadf8 \ud6a8\uacfc\ub97c \ud655\uc778\ud588\ub2e4\u201d\uace0 \uc791\uc131\ud588\ub2e4.<\/p>\n \uc774\uc5b4 \u201c\ub530\ub77c\uc11c \uc6b0\ub9ac\uc758 \uc2e4\ud5d8\uc740 \uc80a\uc740 \ud53c\uac00 \ub274\ub7f0 \uc0ac\uc774\uc758 \uc2dc\ub0c5\uc2a4 \uc5f0\uacb0\uc744 \uc9c1\uc811\uc801\uc73c\ub85c \ucd09\uc9c4\ud558\ub294 \uc5ec\ub7ec \uc694\uc778\uc5d0\uc11c \ud48d\ubd80\ud558\ub2e4\ub294 \uac83\uc744 \ubcf4\uc5ec\uc900\ub2e4\u201d\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n \uc774\ub807\ub4ef \uc5f0\uad6c\uc9c4\uc740 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ub450 \uac00\uc9c0 \ud575\uc2ec \ubb3c\uc9c8\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\uc9c0\ub9cc, \uc774\ub4e4 \ubb3c\uc9c8\uc774 \uc5b4\ub5bb\uac8c \ud68c\ucd98 \ud6a8\uacfc\ub97c \uc77c\uc73c\ud0a4\ub294\uc9c0\ub294 \uc544\uc9c1 \uc815\ud655\ud788 \uc54c \uc218 \uc5c6\ub2e4\uba74\uc11c \ub450 \ubb3c\uc9c8\uc774 \uc0b4\uc544\uc788\ub294 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \ud6a8\uacfc\uac00 \uc788\ub2e4\ub294 \uac83\uc744 \ubcf4\uc5ec\uc8fc\uae30 \uc804\uc5d0 \ub9ce\uc740 \ucd94\uac00 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4\uace0 \uc9c0\uc801\ud588\ub2e4.<\/p>\n \uc608\ub97c \ub4e4\uc5b4 \uadf8\uc911 \ud558\ub098\ub294 \ub450 \ub2e8\ubc31\uc9c8\uc774 \uc0ac\ub78c\uc758 \ud608\uc561\ub1cc\uad00\ubb38(BBB<\/span>)\uc744 \ud1b5\uacfc\ud574 \ub1cc\uc5d0 \uc9c1\uc811 \ub3c4\ub2ec\ud560 \uc218 \uc788\ub294\uc9c0\ub294 \uc544\uc9c1 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\ub2e4\ub294 \uac83\uc774\ub2e4. \ud608\uc561\uacfc \ub1cc \uc870\uc9c1 \uc0ac\uc774\uc5d0 \uc874\uc7ac\ud558\ub294 \ud608\uc561\ub1cc\uad00\ubb38\uc740 \ud608\uc561 \uc18d \ud070 \ubd84\uc790\ub97c \uac78\ub7ec\ub0b4\ub294 \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc84c\ub2e4.<\/p>\n \ud558\uc9c0\ub9cc \ub178\ud654\ub97c \ub9c9\uac70\ub098 \ub418\ub3cc\ub9ac\ub294 \ud654\ud569\ubb3c\uc5d0 \uad00\ud55c \uc5f0\uad6c\ub294 \uc774\ubfd0\ub9cc\uc774 \uc544\ub2c8\ub2e4. \uc7a0\uc7ac\uc801\uc73c\ub85c \uac00\ub2a5\uc131 \uc788\ub294 \ub610 \ub2e4\ub978 \ubb3c\uc9c8\ub85c\ub294 \uc0ac\ub78c\uc758 \uc81c\ub300\ud608 \uc138\ud3ec\uac00 \uc788\ub2e4. \uc774 \uc138\ud3ec\uc5d0\uc11c \ubc1c\uacac\ub41c \u2018TIMP<\/span>1\u2019\uc73c\ub85c \ubd88\ub9ac\ub294 \ud55c \ud654\ud569\ubb3c\uc740 \uc5f0\uad6c\uc5d0\uc11c \ud68c\ucd98 \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4.<\/p>\n \uacfc\ud559\uc790\ub4e4\uc5d0\uac8c \ub192\uc740 \uae30\ub300\ub97c \uac16\uac8c \ud558\ub294 \ub610 \ub2e4\ub978 \ud654\ud569\ubb3c\ub4e4 \uc911\uc5d0\ub294 \uadfc\uc721\uc758 \uc131\uc7a5\uc744 \ucd09\uc9c4\ud558\ub294 \u2018GDF<\/span>11\u2019\uacfc \uae30\uc5b5\uc744 \ud615\uc131\ud558\ub294 \ub1cc\uc758 \uc77c\ubd80\ubd84\uc778 \ud574\ub9c8\uc5d0\uc11c \uc138\ud3ec \uc131\uc7a5\uc5d0 \uc601\ud5a5\uc744 \uc8fc\ub294 \uc131\uc120\uc790\uadf9\ud638\ub974\ubaac\ubd84\ube44\ud638\ub974\ubaac(\uc0dd\uc2dd\uc0d8\uc790\uadf9\ud638\ub974\ubaac\ubd84\ube44\ud638\ub974\ubaac\u00b7GnRH<\/span>)\ub3c4 \uc788\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc84c\ub2e4.<\/p>\n <\/p>\n (\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n <\/p>\n <\/p>\n \uc544\ub798\ub294 2022\ub144 8\uc6d4 11\uc77c \ub274\uc2a4\uc785\ub2c8\ub2e4~<\/p>\n (\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n <\/p>\n \uc80a\uc740 \ud53c\uc758 \ud68c\ucd98 \ud6a8\uacfc\ub77c\uace0 \uc54c\ub824\uc9c4 \uac83\uc774 \uc0ac\uc2e4\uc740 \uc80a\uc740 \ud53c \ub54c\ubb38\uc774 \uc544\ub2c8\ub77c \uc80a\uc740 \ud53c\uac00 \ucd94\uac00\ub418\uba74\uc11c \ub299\uc740 \ud53c\uc758 \ub178\ud654 \uae30\ub2a5\uc774 \ud76c\uc11d\ub41c \ub370 \ub530\ub978 \uac83 \uc544\ub2c8\ub0d0\ub294 \uc758\ubb38\uc774 \uc774\ubc88 \uc5f0\uad6c\uc758 \ucd9c\ubc1c\uc810\uc774\uc5c8\ub2e4. \ud53d\uc0ac\ubca0\uc774<\/em><\/span><\/p>\n \ub178\ud654\ub97c \uc5f0\uad6c\ud558\ub294 \uacfc\ud559\uc790\ub4e4 \uc0ac\uc774\uc5d0\uc11c 2010\ub144\ub300 \uc774\ud6c4 \ud06c\uac8c \uc8fc\ubaa9\ubc1b\uc740 \uac83 \uac00\uc6b4\ub370 \ud558\ub098\uac00 \uc80a\uc740 \ud53c\uc758 \ud68c\ucd98 \ud6a8\uacfc\ub2e4. \ub2f9\uc2dc \ub3d9\ubb3c\uc2e4\ud5d8\uc744 \ud1b5\ud574 \uc774\ub97c \ud655\uc778\ud558\ub294 \uc5f0\uad6c\ub4e4\uc774 \uc5ec\ub7ff \ubc1c\ud45c\ub410\ub2e4.<\/p>\n \uc608\ucee8\ub300 \ubbf8\uad6d \ud53c\uce20\ubc84\uadf8\ub300\uc640 \uc2a4\ud398\uc778 \ubc1c\ub80c\uc2dc\uc544\ub300 \uc5f0\uad6c\uc9c4\uc740 \uc9c0\ub09c\ud574\uc640 \uc62c\ud574 \uac01\uac01 \uc80a\uc740 \uc950\uc758 \ud608\uc561\uc5d0 \uc788\ub294 \uc138\ud3ec \ubc16 \uc18c\ud3ec\uccb4\uc758 \ud68c\ucd98 \ud6a8\uacfc\ub97c \ud655\uc778\ud558\ub294 \uc2e4\ud5d8 \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\ub2e4. \uc80a\uc740 \ud53c\uc758 \ud608\uc7a5\uc774\ub098 \uc904\uae30\uc138\ud3ec\uc5d0\uc11c \uadf8 \uc6d0\uc778\uc744 \ucc3e\ub294 \uc5f0\uad6c\ub3c4 \uc788\uc5c8\ub2e4. 2005\ub144 115\uc0b4\ub85c \uc0ac\ub9dd\ud55c \ub124\ub35c\ub780\ub4dc\uc758 \ud55c \uc5ec\uc131 \ud608\uc561\uc5d0\uc120 \uc904\uae30\uc138\ud3ec\uac00 \ub2e8 2\uac1c\ub9cc \ub0a8\uc544 \uc788\uc5c8\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\ub3c4 \uc788\uc5c8\ub2e4. \uc774\uc5d0 \ub530\ub77c \uc80a\uc740 \ud53c\uc758 \uc5b4\ub5a4 \uc131\ubd84\uc774 \uc774\ub7f0 \ud6a8\uacfc\ub97c \ub0b4\ub294\uc9c0\ub97c \uaddc\uba85\ud558\ub294 \ud6c4\uc18d \uc5f0\uad6c\uac00 \uc774\uc5b4\uc9c0\uace0 \uc788\ub2e4. \uadf8\ub7ec\ub098 \uc80a\uc740 \ud53c \uc694\ubc95\uc740 \uba74\uc5ed\ubc18\uc751 \uac19\uc740 \ubd80\uc791\uc6a9 \ubb38\uc81c\uc640 \ud568\uaed8 \ud68c\ucd98\uc744 \uc704\ud55c \uc218\ud608\uc774 \uacfc\uc5f0 \uc628\ub2f9\ud558\ub290\ub0d0\ub294 \uc724\ub9ac\uc801 \ub17c\ub780\uc758 \ub300\uc0c1\uc774\uae30\ub3c4 \ud558\ub2e4.<\/p>\n \uadf8\ub807\ub2e4\uba74 \uac70\uafb8\ub85c \ub299\uc740 \ud53c\ub97c \uc8fc\uc785\ud558\uba74 \uc5b4\ub5a4 \uc77c\uc774 \ubc8c\uc5b4\uc9c8\uae4c?<\/p>\n \uace0\ub824\ub300 \uc758\ub300\uc640 \ubbf8\uad6d \ubc84\ud074\ub9ac\uce98\ub9ac\ud3ec\ub2c8\uc544\ub300(UC<\/span>\ubc84\ud074\ub9ac) \uacf5\ub3d9\uc5f0\uad6c\uc9c4\uc774 \uc80a\uc740 \uc950\uc5d0\uac8c \ub299\uc740 \uc950\uc758 \ud53c\ub97c \uc218\ud608\ud558\ub294 \uc2e4\ud5d8\uc744 \ud55c \uacb0\uacfc \uc80a\uc740 \uc950\uc758 \ub178\ud654 \uc18d\ub3c4\uac00 \ube68\ub77c\uc9c4 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4\uace0 7\uc6d429\uc77c \uad6d\uc81c\ud559\uc220\uc9c0 \u2018\ub124\uc774\ucc98 \ub300\uc0ac\u2019 \uc628\ub77c\uc778\uc5d0 \ubc1c\ud45c\ud588\ub2e4.<\/p>\n \uc80a\uc740 \ud53c\ub97c \uc8fc\uc785\ud588\uc744 \ub54c\uc640 \uc815\ubc18\ub300 \ud6a8\uacfc\uac00 \ub098\ud0c0\ub09c \uac83\uc774\ub2e4. \uc774\ub294 \uc138\ud3ec \ub178\ud654\uac00 \ub2e8\uc21c\ud788 \uc624\ub7ab\ub3d9\uc548 \uc4f0\uba74\uc11c \ub2f3\uc544 \ud574\uc9c0\ub294 \ub9c8\ubaa8 \ud604\uc0c1\uc774 \uc544\ub2d8\uc744 \uc2dc\uc0ac\ud55c\ub2e4.<\/p>\n \uadf8\ub3d9\uc548 \uc80a\uc740 \uc950\uc640 \ub299\uc740 \uc950 \uc0ac\uc774\uc758 \uc0c1\ud638 \uc218\ud608 \uc2e4\ud5d8\uc5d0\uc11c \ub299\uc740 \ud53c\ub97c \uc218\ud608\ubc1b\uc740 \uc80a\uc740 \uc950\uc758 \uac74\uac15\uc774 \uc545\ud654\ud55c\ub2e4\ub294 \uac74 \uc774\ubbf8 \ud655\uc778\ub41c \uc0ac\uc2e4\uc774\ub2e4. \uadf8\ub7ec\ub098 \uc5f0\uad6c\uc758 \ucd08\uc810\uc740 \uc8fc\ub85c \ub299\uc740 \uc950\uc758 \ud68c\ucd98 \ud6a8\uacfc\uc5d0 \ub9de\ucdb0\uc838 \uc788\uc5c8\uace0, \uc80a\uc740 \uc950\uc5d0\uac8c\uc11c \uc77c\uc5b4\ub098\ub294 \ud6a8\uacfc\uc5d0 \ub300\ud574\uc11c\ub294 \uc0c1\uc138\ud55c \ubd84\uc11d\uc774 \uc774\ub904\uc9c0\uc9c0 \uc54a\uc558\ub2e4.<\/p>\n \uc5f0\uad6c\uc9c4\uc740 \uc774\ubc88 \uc2e4\ud5d8\uc5d0\uc11c \uc774 \ubd80\ubd84\uc744 \uc9d1\uc911\uc801\uc73c\ub85c \uc0b4\ud3b4\ubd24\ub2e4. \ub17c\ubb38 \uc81c1\uc800\uc790\uc778 \uc804\uc625\ud76c \uace0\ub824\ub300 \uc758\ub300 \uad50\uc218(\uc758\uc0dd\uba85\uacfc\ud559)\uc5d0 \ub530\ub974\uba74 \uc774\ubc88 \uc5f0\uad6c\uc758 \ucd9c\ubc1c\uc810\uc740 \u201c\uadf8\ub3d9\uc548 \uc80a\uc740 \ud53c\uc758 \ud68c\ucd98 \ud6a8\uacfc\ub77c\uace0 \uc54c\ub824\uc9c4 \uac83\uc774 \uc0ac\uc2e4\uc740 \uc80a\uc740 \ud53c \ub54c\ubb38\uc774 \uc544\ub2c8\ub77c \uc80a\uc740 \ud53c\uac00 \ucd94\uac00\ub418\uba74\uc11c \ub299\uc740 \ud53c\uc758 \ub178\ud654 \uae30\ub2a5\uc774 \ud76c\uc11d\ub41c \ub370 \ub530\ub978 \uac83 \uc544\ub2c8\ub0d0\ub294 \uc758\ubb38\u201d\uc774\uc5c8\ub2e4.<\/p>\n \uc80a\uc740 \uc950\uc5d0 \uc8fc\uc785\ud55c \ub299\uc740 \ud53c\uc758 \ub178\ud654 \ud6a8\uacfc\ub294 \uac04\uc5d0\uc11c \ud2b9\ud788 \ub450\ub4dc\ub7ec\uc84c\ub2e4. \ud53d\uc0ac\ubca0\uc774<\/em><\/span><\/p>\n \uc5f0\uad6c\uc9c4\uc740 \uc0dd\ud6c4 \uc11d\ub2ec \ub41c \uc80a\uc740 \uc950\uc5d0\uac8c \uc0dd\ud6c4 2\ub144\uc774 \uac70\uc758 \ub2e4 \ub41c \ub299\uc740 \uc950\uc758 \ud53c\ub97c \uc218\ud608\ud588\ub2e4.<\/p>\n 2\uc8fc\uac00 \uc9c0\ub098\uc790 \uc80a\uc740 \uc950\uc758 \ubab8\uc5d0\uc11c \ub178\ud654 \uc138\ud3ec \uc218\uac00 \ud06c\uac8c \ub298\uc5b4\ub0ac\ub2e4. \uac04\uacfc \uc2e0\uc7a5 \ub4f1 \uc5ec\ub7ec \uae30\uad00\uc758 \uc138\ud3ec\uac00 \uc190\uc0c1\uc744 \uc785\uace0 \uc138\ud3ec \ubd84\uc5f4\uc744 \uba48\ucdc4\ub2e4. \uadf8\ub807\ub2e4\uace0 \uc8fd\uc740 \uac83\ub3c4 \uc544\ub2cc \uc77c\uc885\uc758 \uc880\ube44\uc138\ud3ec\uac00 \ub410\ub2e4. \uc774\ub294 \ub178\ud654\uac00 \uc2dc\uc791\ub420 \ub54c \ub098\ud0c0\ub098\ub294 \ud604\uc0c1\uc774\ub2e4. \ud2b9\ud788 \uac04\uacfc \ub1cc\uc5d0\uc11c \uc774\ub7f0 \ud604\uc0c1\uc774 \ub450\ub4dc\ub7ec\uc84c\ub2e4.<\/p>\n \uc80a\uc740 \uc950\uc758 \uadfc\ub825\ub3c4 \ub299\uc740 \uc950\uc758 \ud53c\ub97c \uc218\ud608\ud55c \ub4a4 \uc57d\ud574\uc84c\ub2e4. \ub098\uc774\ub97c \ub9ce\uc774 \uba39\uc9c0 \uc54a\uc558\ub294\ub370\ub3c4 \uc138\ud3ec \ub178\ud654\uac00 \uc9c4\ud589\ub41c \uac83\uc774\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \u201c\uc804\uccb4\uc801\uc73c\ub85c \ub299\uc740 \ud53c \uc8fc\uc785\uc73c\ub85c \uc778\ud55c \ubd80\uc815\uc801 \ud6a8\uacfc\uc758 \uc815\ub3c4\uac00 \uc80a\uc740 \ud53c \uc8fc\uc785\uc5d0\uc11c \ubcf4\uc600\ub358 \uae0d\uc815\uc801 \ud6a8\uacfc\uc640 \uac19\uac70\ub098 \uadf8 \uc774\uc0c1\uc774\uc5c8\ub2e4\u201d\uace0 \ubc1d\ud614\ub2e4.<\/p>\n \uc6d0\uc778\uc774 \ubb58\uae4c? \uc5f0\uad6c\uc9c4\uc740 \ud608\uc561 \ub0b4 \ub178\ud654 \uc138\ud3ec\uc5d0\uc11c \ubd84\ube44\ub418\ub294 \uc778\uc790\ub4e4\uc774 \ud608\uc561 \uc18d\uc744 \uc21c\ud658\ud558\uba74\uc11c \uc80a\uc740 \uc950\uc758 \uc138\ud3ec\uc640 \uc870\uc9c1\uc744 \ub178\ud654\uc2dc\ud0a4\ub294 \u2018\ub178\ud654 \uc804\uc774\u2019\ub97c \uc77c\uc73c\ud0a4\ub294 \uac83\uc73c\ub85c \ubcf4\uc778\ub2e4\uace0 \ubc1d\ud614\ub2e4. \uc554 \uc720\ubc1c \ubb3c\uc9c8\uc774 \ud608\uc561\uc744 \ud0c0\uace0 \uc804\uc2e0\uc73c\ub85c \ud37c\uc9c0\uba74\uc11c \uc554\uc744 \uc804\uc774\uc2dc\ud0a4\ub294 \uac83\uacfc \uac19\uc740 \uc774\uce58\ub2e4.<\/p>\n \ub178\ud654 \uc138\ud3ec\ub294 \uc99d\uc2dd\uc744 \uba48\ucd94\ub294 \ub300\uc2e0 \uc5fc\uc99d\uc131 \ubb3c\uc9c8\uacfc \ub2e8\ubc31\uc9c8 \ubd84\ud574 \ud6a8\uc18c \ub4f1\uc744 \ubd84\ube44\ud55c\ub2e4. \uc774\ub97c \ub178\ud654\uc5f0\uad00 \ubd84\ube44\ud45c\ud604\ud615(SASP<\/span>)\ub77c\uace0 \ubd80\ub978\ub2e4. \uadf8\ub7ec\ub098 \uc774\ubc88 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uad6c\uccb4\uc801\uc73c\ub85c \ub178\ud654 \uc138\ud3ec\uc5d0\uc11c \ubd84\ube44\ub418\ub294 \uc5b4\ub5a4 \ubb3c\uc9c8\uc774 \ub178\ud654 \uc804\uc774\ub97c \uc77c\uc73c\ud0a4\ub294\uc9c0\ub294 \uaddc\uba85\ud558\uc9c0 \ubabb\ud588\ub2e4.<\/p>\n \ub098\uc774 \ub9ce\uc740 \uc950\uc758 \ud608\uc561 \uc18d\uc5d0\uc11c \uc21c\ud658\ud558\ub294 \uac01\uc885 \uc778\uc790\ub4e4\uc774 \uc5b4\ub9b0 \uc950\uc758 \ud608\uad00\uc5d0 \ub4e4\uc5b4\uac00\uba74 \uc5b4\ub9b0 \uc950\uc758 \uadfc\ub825 \uac10\uc18c \ub4f1 \ub178\ud654\uac00 \uac00\uc18d\ud654\ud588\ub2e4. \ubc18\ub300\ub85c \ub098\uc774 \ub9ce\uc740 \uc950\uc5d0 \ub178\ud654\uc138\ud3ec\ub97c \uc5c6\uc560\ub294 ‘\uc138\ub180\ub9ac\ud2f1 \ubb3c\uc9c8’ \uc8fc\uc785\ud558\uba74 \ub178\ud654\ub85c \uc778\ud55c \uc99d\uc0c1\uc744 \ub9c9\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub410\ub2e4. \uc804\uc625\ud76c \uad50\uc218 \uc81c\uacf5<\/em><\/span><\/p>\n \uc804 \uad50\uc218\ub294 \u201c\uc774\ubc88 \uc5f0\uad6c\ub294 \ub178\ud654 \uacfc\uc815\uc774 \ub2e8\uc21c\ud788 \uc0dd\ubb3c\ud559\uc801 \uc2dc\uac04\uc758 \ud750\ub984\uc5d0 \uc758\ud55c \uac83\ub9cc\uc774 \uc544\ub2c8\ub77c \ub178\ud654 \uc804\uc774\ub97c \ud1b5\ud574 \uac00\uc18d\ub420 \uc218 \uc788\ub2e4\ub294 \uc0c8\ub85c\uc6b4 \ud328\ub7ec\ub2e4\uc784\uc744 \uc81c\uc2dc\ud55c \ub370 \uc758\ubbf8\uac00 \uc788\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4. \uadf8\ub3d9\uc548\uc758 \ub178\ud654 \uce58\ub8cc \uc5f0\uad6c\ub294 \ub178\ud654 \u2018\uc138\ud3ec\u2019 \uc790\uccb4\ub97c \ucc98\ub9ac\ud558\ub294 \ub370 \ucd08\uc810\uc744 \ub9de\ucdc4\uc73c\ub098, \uc774\ubc88 \uc5f0\uad6c\ub294 \ub178\ud654 \u2018\uc804\uc774\u2019\ub77c\ub294 \uba54\uce74\ub2c8\uc998\uc744 \ub2e4\ub8ec\ub2e4\ub294 \uc810\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uac1c\ub150\uc758 \uc811\uadfc\ubc95\uc774\ub77c\ub294 \uac83\uc774\ub2e4.<\/p>\n \uacf5\ub3d9\uc5f0\uad6c\uc790\uc778 \ucf58\ubcf4\uc774 \uad50\uc218\ub294 \uacfc\ud559\uc804\ubb38\uc9c0 \u2018\ub274\uc0ac\uc774\uc5b8\ud2f0\uc2a4\ud2b8\u2019\uc5d0 \u201c\uc138\ud3ec \ub178\ud654\ub294 \ub178\ud654 \uacfc\uc815\uc758 \uc77c\ubd80\uc77c \ubfd0\u201d\uc774\ub77c\uba70 \u201c\uc774\ubc88 \uc5f0\uad6c\ub294 \uadf8\ub3d9\uc548\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \ub178\ud654\uc138\ud3ec\ub97c \uc81c\uac70\ud574\uc8fc\ub294 \uc57d\ubb3c(\uc138\ub180\ub9ac\ud2f1)\uc774 \uae30\ub300\ud588\ub358 \uac83\ubcf4\ub2e4 \ub35c \uc131\uacf5\uc801\uc774\uc5c8\ub358 \uc774\uc720\ub97c \uc124\uba85\ud574\uc90c\uc73c\ub85c\uc368 \uc5f0\uad6c\uc758 \uc0c8\ub85c\uc6b4 \uc9c0\ud3c9\uc744 \uc5f4\uc5c8\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n \uc804 \uad50\uc218\ub294 \u201c\uc9c0\uae08\uae4c\uc9c0 \ub178\ud654 \uc138\ud3ec\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uac1c\ubc1c\ud55c \uc138\ub180\ub9ac\ud2f1 \uc57d\ubb3c\uc774 \ub9ce\uc740 \uc784\uc0c1\uc2e4\ud5d8\uc5d0\uc11c \uc2e4\ud328\ud588\ub2e4\u201d\uba70 \u201c\uc774\ubc88 \uc5f0\uad6c\uc5d0\uc11c \uc138\ud3ec\uac00 \uc544\ub2cc \uc138\ud3ec \uc720\ub798 \ubb3c\uc9c8\uc744 \ub9e4\uac1c\ub85c \ub178\ud654 \uc804\uc774\uac00 \ub2e4\uc591\ud55c \uc870\uc9c1\uc5d0\uc11c \uc77c\uc5b4\ub09c \uacfc\uc815\uc774 \ubc1d\ud600\uc9c4 \ub9cc\ud07c \uc138\ub180\ub9ac\ud2f1 \ubb3c\uc9c8\uc758 \uac1c\ubc1c \ucd08\uc810\uc774 \ub2ec\ub77c\uc838\uc57c \ud560 \ud544\uc694\uac00 \uc788\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n \uc774\ub294 \ub178\ud654 \uc9c8\ud658 \uce58\ub8cc\uc5d0\uc11c \ud608\uc561 \ub0b4\uc758 \ub178\ud654 \uc720\ubc1c \uc778\uc790\ub97c \uc81c\uac70\ud558\ub294 \uc57d\ubb3c \uac1c\ubc1c\uc774\ub77c\ub294 \uc0c8\ub85c\uc6b4 \ubaa9\ud45c\ub97c \uc81c\uc2dc\ud574\uc900\ub2e4. \uc804\uc625\ud76c \uad50\uc218\ub294 \u201c\ub2e4\uc74c \uc5f0\uad6c \uacfc\uc81c\ub294 \uad6c\uccb4\uc801\uc73c\ub85c \ub178\ud654 \uc804\uc774\ub97c \uc77c\uc73c\ud0a4\ub294 \ubb3c\uc9c8\uc774 \ubb34\uc5c7\uc778\uc9c0\ub97c \uc54c\uc544\ub0b4\ub294 \uac83\u201d\uc774\ub77c\uace0 \ub367\ubd99\uc600\ub2e4.<\/p><\/div>\n<\/div>\n<\/div>\n <\/p>\n <\/p>\n <\/p>\n \uc544\ub798\ub294 2023\ub144 1\uc6d4 27\uc77c \ub274\uc2a4\uc785\ub2c8\ub2e4~<\/p>\n (\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n <\/p>\n \ubbf8\uad6d\uc758 \uc2a4\ud0c0\ud2b8\uc5c5 \u2018\ub9ac\uc8fc\ubc84\ub124\uc774\ud2b8 \ubc14\uc774\uc624\u2019\uac00 \uc0dd\uc950\uc5d0\uac8c \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uc720\uc804\uc790\ub97c \ud22c\uc5ec\ud55c \uc2e4\ud5d8\uc5d0\uc11c \uc218\uba85 \uc5f0\uc7a5 \uac00\ub2a5\uc131\uc774 \ud655\uc778\ub410\ub2e4.\u00a0photo<\/span>\u00a0\uac8c\ud2f0\uc774\ubbf8\uc9c0<\/em><\/span><\/p>\n <\/p>\n<\/div>\n \ub098\uc774\uac00 \ub4e4\uc218\ub85d \ub178\ud654\ub3fc\uac00\ub294 \uac83\uc740 \ub9cc\uace0\uc758 \uc9c4\ub9ac\ub2e4. \uc720\uc804\uc790 \ubc1c\ud604\uc774 \uc870\uc808\ub418\uc9c0 \uc54a\uc544 \uc2e0\uccb4\uc758 \uc5ec\ub7ec \uae30\uad00 \uc2dc\uc2a4\ud15c\uacfc \ub124\ud2b8\uc6cc\ud06c\uac00 \uace0\uc7a5\ub098\uae30 \ub54c\ubb38\uc774\ub2e4. \uc774\ub294 \uc218\uba85\uc744 \ub2e8\ucd95\uc2dc\ud0a4\ub294 \uc694\uc778\uc774 \ub420 \uc218 \uc788\ub2e4. \uadf8\ub7f0\ub370 \ucd5c\uadfc \uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\uc774\ub77c\ub294 \ubc29\uc2dd\uc744 \ud1b5\ud574 \ub299\uc740 \uc0dd\uc950\uc758 \uc218\uba85\uc744 \uc5f0\uc7a5\ud55c \uc2e4\ud5d8\uc774 \uc131\uacf5\ud574 \uc218\uba85 \uc5f0\uc7a5\uc744 \uc6d0\ud558\ub294 \uc0ac\ub78c\ub4e4\uc758 \uc8fc\ubaa9\uc744 \ub04c\uace0 \uc788\ub2e4. \uc774 \uae30\uc220\uc740 \ub178\ud654\uac00 \ubd88\uac00\ud53c\ud558\uc9c0 \uc54a\uc744 \uc218\ub3c4 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\ub2e4.<\/p>\n <\/p>\n<\/div>\n \uc0ac\ub78c 77\uc0b4\uc5d0 \ud574\ub2f9\ud558\ub294 \uc0dd\uc950 \uc218\uba85 \ub450 \ubc30\ub85c<\/strong><\/p>\n \uc6b0\ub9ac \ubab8\uc758 \uae30\ubcf8 \ub2e8\uc704\ub294 \uc138\ud3ec\ub2e4. \uc0ac\ub78c\uc740 \uc8fc\uae30\uc801\uc73c\ub85c \uc138\ud3ec\ubd84\uc5f4\uc744 \ud1b5\ud574 \uc0dd\uba85\uc744 \uc720\uc9c0\ud55c\ub2e4. \ud558\uc9c0\ub9cc \ub178\ud654\ub294 \uc138\ud3ec\uac00 \ubd84\uc5f4\ud560 \uc218 \uc788\ub294 \ub2a5\ub825\uc744 \uac10\ud1f4\uc2dc\ud0a8\ub2e4. \ub178\ud654\ub294\u00a0DNA<\/span>\uc5d0 \uc788\ub294 \uc720\uc804\uc790\uc5d0 \uc5ec\ub7ec \uc720\ud615\uc758 \ub3cc\uc5f0\ubcc0\uc774\uac00 \uc9c0\uc18d\uc801\uc73c\ub85c \uc77c\uc5b4\ub098\uba74\uc11c \ucd95\uc801\ub3fc \ubc1c\uc0dd\ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\ub2e4.<\/p>\n \uc720\uc804\uc790\uc5d0 \ub2f4\uae34 \uc815\ubcf4\uac00 \uc774\ub807\uac8c \ub2e4\ub978 \uac83\uc73c\ub85c \ubc14\ub00c\uba74, \uc138\ud3ec\uac00 \uc6d0\ud558\ub294 \uc815\ubcf4\ub97c \ucc3e\uc544\ub0b4\uc9c0 \ubabb\ud574 \uc81c \uae30\ub2a5\uc744 \uc783\uac8c \ub41c\ub2e4. \ub9c8\uce58 \uc624\ub798 \uc0ac\uc6a9\ud55c\u00a0DVD<\/span>\u00a0\ud45c\uba74\uc774 \uae01\ud600 \uc790\uad6d\ub4e4\uc774 \ub9ce\uc774 \uc0dd\uae34 \uacb0\uacfc \ub2f4\uae34 \ub514\uc9c0\ud138 \uc815\ubcf4\ub97c \uc81c\ub300\ub85c \uc77d\uc5b4\ub0b4\uc9c0 \ubabb\ud558\ub294 \uac83\uacfc \uac19\ub2e4. \ub178\ud654\ub294 \uc9c8\ubcd1\uc774 \uc544\ub2c8\uc9c0\ub9cc \uc138\ud3ec\uc758 \uae30\ub2a5\uc774 \uc81c\ub300\ub85c \uc791\ub3d9\ud558\uc9c0 \uc54a\uc740 \uacb0\uacfc \uc9c8\ubcd1\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc704\ud5d8\uc774 \ub192\ub2e4.<\/p>\n \uadf8\ub3d9\uc548 \uacfc\ud559\uc790\ub4e4\uc740 \ub178\ud654\uc758 \uc6d0\uc778\uc744 \ubc1d\ud788\ub824\ub294 \uc5f0\uad6c\ub97c \uacc4\uc18d\ud574\uc654\ub2e4. \ub610 \ubc18\ub300\ub85c \ub178\ud654\ub97c \uba48\ucd94\uac70\ub098 \uc5ed\uc804\ub418\ub294 \uccad\ucd98\uc694\ubc95\uc744 \uc54c\uc544\ub0b4\uae30 \uc704\ud574 \uc9c0\uae08\uae4c\uc9c0\ub3c4 \ub178\ub825\ud558\uace0 \uc788\ub2e4. \uadf8\ub7f0 \uac00\uc6b4\ub370 \uc81c \uae30\ub2a5\uc744 \ubc1c\ud718\ud558\uc9c0 \ubabb\ud558\ub294 \ub178\ud654 \uc138\ud3ec\ub97c \uc7ac(\u518d)\ud504\ub85c\uadf8\ub798\ubc0d\ud558\uba74 \uc80a\uc740 \uc0c1\ud0dc\ub85c \ub418\ub3cc\ub824\uc9c4\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1d\ud78c \uc5f0\uad6c\ud300\uc774 \ub4f1\uc7a5\ud588\ub2e4. \ubbf8\uad6d\uc758 \uc2a4\ud0c0\ud2b8\uc5c5 ‘\ub9ac\uc8fc\ubc84\ub124\uc774\ud2b8 \ubc14\uc774\uc624(Rejubenate<\/span>\u00a0Bio<\/span>)’\uac00 \uadf8 \uc8fc\uc778\uacf5\uc774\ub2e4. \uc5f0\uad6c\ud300\uc740 \uc0dd\uc950\ub97c \ub300\uc0c1\uc73c\ub85c \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uc720\uc804\uc790\ub97c \ud22c\uc5ec\ud55c \uc2e4\ud5d8\uc5d0\uc11c \uc218\uba85 \uc5f0\uc7a5\uc758 \uac00\ub2a5\uc131\uc744 \ud655\uc778\ud588\ub2e4. \uadf8 \ub0b4\uc6a9\uc740 \uc0ac\uc804 \uacf5\uc720 \uc0ac\uc774\ud2b8\uc778 \ubc14\uc774\uc624\uc544\uce74\uc774\ube0c(BioRxiv<\/span>)\uc5d0 \uacf5\uac1c\ub410\ub2e4.<\/p>\n \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\uc774\ub780 \ub178\ud654\ub41c \uc138\ud3ec\uc5d0 \uc7ac\ud504\uadf8\ub798\ubc0d \uc778\uc790\ub4e4\uc744 \uc9d1\uc5b4\ub123\uc5b4 \uc80a\uc740 \uc0c1\ud0dc\ub85c \ub418\ub3cc\ub9ac\ub294 \uae30\uc220\uc774\ub2e4. \ud55c\ub9c8\ub514\ub85c \uccb4\uc138\ud3ec\ub97c \uc904\uae30\uc138\ud3ec\ub85c \ub418\ub3cc\ub9ac\ub294 \uacfc\uc815\uc774\ub2e4. \uc644\uc804\ud55c \uc6d0\uc2dc\uc0c1\ud0dc\uc758 \ubc30\uc544\uc904\uae30\uc138\ud3ec \ub2e8\uacc4\uac00 \uc544\ub2cc \uc911\uac04 \ub2e8\uacc4\ub85c \ub418\ub3cc\ub824 \uc138\ud3ec\uc758 \ud2b9\uc218 \uae30\ub2a5\uc740 \uc720\uc9c0\ud558\uba74\uc11c \ub178\ud654 \uc2dc\uacc4\ub97c \ub418\ub3cc\ub9ac\ub294 \uac83\uc774\ub2e4. \uc544\uc8fc \uc624\ub798\ub41c \uc138\ud3ec\ub3c4 \uc80a\uac8c \uc791\uc6a9\ud558\ub294 \uc904\uae30\uc138\ud3ec\ub85c \ubcc0\ud55c\ub2e4.<\/p>\n \uc5f0\uad6c\ud300\uc740 \uc794\uc874 \uc218\uba85\uc774 \uc5bc\ub9c8 \ub0a8\uc9c0 \uc54a\uc740 124\uc8fc \ucc28 \ub41c \uc0dd\uc950\ub97c \ub450 \uadf8\ub8f9\uc73c\ub85c \ub098\ub220 \ud55c\ucabd\uc5d0\ub9cc 3\uac1c\uc758 \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uc720\uc804\uc790\ub97c \uc8fc\uc0ac\ud588\ub2e4. \uc0ac\ub78c\uc73c\ub85c \uce58\uba74 77\uc0b4\uc5d0 \ud574\ub2f9\ud558\ub294 \uc0dd\uc950\ub4e4\uc774\ub2e4. \uadf8 \uacb0\uacfc \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uc720\uc804\uc790 \uce58\ub8cc\ub97c \ubc1b\uc740 \uc0dd\uc950\ub4e4\uc740 \uc218\uba85\uc774 2\ubc30\ub85c \ub298\uc5b4\ub0ac\ub2e4. \uc774\ub4e4 \uc0dd\uc950\ub294 \ud3c9\uade0 18\uc8fc\ub97c \ub354 \uc0b0 \ubc18\uba74 \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uc720\uc804\uc790 \uc57d\ubb3c\uc8fc\uc0ac\ub97c \ub9de\uc9c0 \uc54a\uc740 \ub300\uc870\uad70 \uc950\ub294 9\uc8fc \ub9cc\uc5d0 \uc8fd\uc5c8\ub2e4. \uc0dd\uc950\ub294 \uc774\ubbf8 124\uc8fc\uc600\uc73c\ubbc0\ub85c \uc218\uba85\uc774 7%\ub9cc \uc99d\uac00\ud55c \uc148\uc774\ub2e4.<\/p>\n \ub9ac\uc8fc\ubc84\ub124\uc774\ud2b8 \ubc14\uc774\uc624\uc758 \ucd5c\uace0\uacfc\ud559\ucc45\uc784\uc790(CSO<\/span>) \ub178\ub77c \ub370\uc774\ube44\uc2a8\uc740 \uc774\ub7ec\ud55c \uc5f0\uad6c \uacb0\uacfc\uc5d0 \ub300\ud574 \ub3d9\ubb3c\uc758 \ub098\uc774 \uc5ed\uc804\uc744 \uc785\uc99d\ud55c \uac83\uc774\ub098 \ub2e4\ub984\uc5c6\ub2e4\uace0 \ub9d0\ud55c\ub2e4. \uadf8\ub4e4\uc758 \uc5f0\uad6c\ub294 \uace0\ub839\uce35\uc5d0 \uc2e4\uc81c\ub85c \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\ub294 \uc77c\uc774\ub77c\ub294 \uac78 \ubcf4\uc5ec\uc8fc\ub824\ub294 \ubaa9\uc801\uc5d0\uc11c \uc2dc\uc791\ud588\ub294\ub370, \uc138\ud3ec \uc7ac\ud504\uadf8\ub798\ubc0d\uc774\ub77c\ub294 \uac15\ub825\ud55c \uae30\uc220\uc774 \uc720\uc804\uc790 \ubc1c\ud604 \ub124\ud2b8\uc6cc\ud06c\ub97c \ucd5c\uc801\uc758 \uae30\ub2a5\uc73c\ub85c \ub418\ub3cc\ub9ac\uba74\uc11c \ub178\ud654\uac00 \uc218\uba85\uacfc \uac74\uac15 \uc218\uba85\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \ucd5c\uc18c\ud654\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\ub2e4\ub294 \uac8c \uadf8\uc758 \uc124\uba85\uc774\ub2e4.<\/p>\n \ub178\ud654\ub97c \uc608\ubc29\ud560 \uc218\ub294 \uc5c6\ub2e4. \ud558\uc9c0\ub9cc \uc774\ubc88 \uc5f0\uad6c\ub294 \ubd80\ubd84\uc801 \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\uc774 \ub178\ud654 \uad00\ub828 \uc9c8\ubcd1\uc758 \uc5ed\uc804\ubfd0 \uc544\ub2c8\ub77c \uc218\uba85 \uc5f0\uc7a5\uc758 \uce58\ub8cc\ubc95\uc774 \ub420 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4. \uc774 \uc5f0\uad6c\uac00 \uac80\uc99d\ub418\ub824\uba74 \ucd94\uac00\uc801\uc778 \uc791\uc5c5\uc774 \ud544\uc694\ud558\ub2e4. \uc5f0\uad6c\ud300\uc758 \uac80\uc99d \uacfc\uc815\uc5d0\uc11c \uae0d\uc815\uc801\uc778 \uba54\uc2dc\uc9c0\uac00 \ub098\uc628\ub2e4\uba74 \uc0ac\ub78c\uc5d0\uac8c \uc774 \uae30\uc220\uc744 \uc801\uc6a9\ud560 \uac00\ub2a5\uc131\uc774 \ub192\ub2e4. \ub9cc\uc77c \uc0ac\ub78c\uc758 \uc720\uc804\uc790\ub97c \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\ud574 \uc138\ud3ec\ub97c \uc80a\uc740 \uc0c1\ud0dc\ub85c \ub418\ub3cc\ub9ac\ub294 \ub370 \uc131\uacf5\ud55c\ub2e4\uba74, \uadf8\ub798\uc11c \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA<\/span>) \uc2b9\uc778\uc744 \uc704\ud55c \uc784\uc0c1\uc2dc\ud5d8\uc5d0 \ub4e4\uc5b4\uac04\ub2e4\uba74 \uadf8 \uac00\uce58\ub294 \uc5c4\uccad \ub192\uc544\uc9c8 \uc218\ubc16\uc5d0 \uc5c6\ub2e4. \uc0dd\uba85 \uc5f0\uc7a5\uc5d0 \ub3c8\uc744 \uc544\ub084 \uc0ac\ub78c\uc740 \uc5c6\uc744 \ud14c\ub2c8 \ub9d0\uc774\ub2e4.<\/p>\n \ubc18\uba74 \uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uae30\uc220\uc744 \uc2e4\uc81c\ub85c \ub178\ud654 \ubc29\uc9c0\uc5d0 \ud65c\uc6a9\ud558\uae30\uc5d0\ub294 \uc544\uc9c1 \uc774\ub974\ub2e4\ub294 \uc758\uacac\ub3c4 \ub9cc\ub9cc\ucc2e\ub2e4. \uac15\ud55c \ub3c5\uc131\uc73c\ub85c \uc2e4\ud5d8\ub3d9\ubb3c\uc774 \uc8fd\uac70\ub098 \uc554\uc138\ud3ec\uac00 \ubc1c\uc0dd\ud560 \uc704\ud5d8\uc131\uc774 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4. \uc774\uc5d0 \ub300\ud574 \uc5f0\uad6c\ud300\uc740 \uc7a5\uae30\uac04 \uce58\ub8cc\ud558\uba74 \uc554\uc744 \uc720\ubc1c\ud558\uc9c0 \uc54a\uace0 \ub3d9\ubb3c\uc758 \uc870\uc9c1\uc5d0 \uc0c1\ub2f9\ud55c \ud68c\ucd98 \ud6a8\uacfc\uac00 \ub098\ud0c0\ub0a0 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\ub2e4\uba70 \uce58\ub8cc \uc2dc\uac04\uc774 \uae38\uc218\ub85d \ub354 \uc88b\uc740 \uacb0\uacfc\ub97c \uc5bb\uac8c \ub420 \uac83\uc774\ub77c\uace0 \ubc1d\ud788\uace0 \uc788\ub2e4. \uc5f0\uad6c\ud300\uc758 \ucd94\uac00 \uc5f0\uad6c\ub85c \ub178\ud654\ub97c \ub418\ub3cc\ub9ac\ub294 \uce58\ub8cc\uac00 \uace7 \uc2e4\ud604\ub420 \uc218 \uc788\uae30\ub97c \uae30\ub300\ud55c\ub2e4.<\/p>\n \ubbf8\uad6d \uc0cc\ub514\uc5d0\uc774\uace0\uc5d0 \uc788\ub294 \uc2a4\ud0c0\ud2b8\uc5c5 \u2018\ub9ac\uc8fc\ubc84\ub124\uc774\ud2b8 \ubc14\uc774\uc624\u2019.\u00a0photo<\/span>\u00a0\ud2b8\uc704\ud130<\/em><\/span><\/p>\n<\/div>\n <\/p>\n 2012\ub144 \ub178\ubca8\uc0c1 \ud0c4 \uc57c\ub9c8\ub098\uce74 \uc5f0\uad6c\uac00 \uae30\ubc18<\/strong><\/p>\n \uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\uc740 \uc77c\ubcf8 \uad50\ud1a0\ub300\uc758 \uc57c\ub9c8\ub098\uce74 \uc2e0\uc57c \uad50\uc218\uc758 \uc5f0\uad6c\ub97c \uae30\ubc18\uc73c\ub85c \ud55c\ub2e4. \uadf8\ub294 2006\ub144 \uc0dd\uc950\uc758 \ud53c\ubd80\uc138\ud3ec\uc5d0 4\uac1c\uc758 \ud2b9\uc815 \uc720\uc804\uc790(Oct4<\/span>,\u00a0Sox2<\/span>,\u00a0c-Myc<\/span>,\u00a0Klf4<\/span>)\ub97c \uc8fc\uc785\ud574 \uc5b4\ub5a4 \uc138\ud3ec\ub85c\ub3c4 \ubd84\ud654\ud560 \uc218 \uc788\ub294 \uc720\ub3c4\ub9cc\ub2a5\uc904\uae30\uc138\ud3ec(iPS<\/span>)\ub97c \ucc98\uc74c\uc73c\ub85c \ub9cc\ub4e4\uc5c8\ub2e4. \uc131\uc219\ud55c \uc138\ud3ec\uac00 \ubd84\ud654 \uac00\ub2a5\ud55c \ubbf8\uc131\uc219 \uc138\ud3ec\ub85c \ubc14\ub00c\ub3c4\ub85d \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\ud560 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud55c \uac83\uc774\ub2e4. \uc774 \uacf5\ub85c\ub85c \uadf8\ub294 2012\ub144 \ub178\ubca8\uc0c1\uc744 \ubc1b\uc558\ub2e4.<\/p>\n \ub9ac\uc8fc\ubc84\ub124\uc774\ud2b8 \ubc14\uc774\uc624 \uc5f0\uad6c\ud300\uc758 \uc5f0\uad6c\ub294 \ubc14\ub85c \uc57c\ub9c8\ub098\uce74 \uad50\uc218\uac00 \uc138\ud3ec \uc5ed\ubd84\ud654\uc5d0 \uc4f4 \uc720\uc804\uc790 \uc694\uc778\uc744 \uc801\uc6a9\ud588\ub2e4. \uc774\uc804\uc758 \uc5f0\uad6c\ub4e4\uc774 \uc77c\ubc18\uc801\uc73c\ub85c \uc904\uae30\uc138\ud3ec\ub85c \ub418\ub3cc\ub9ac\uc9c0 \uc54a\uace0 \uc720\uc804\uc790 \ubcc0\ud615\uc744 \ub418\ub3cc\ub9ac\ub294 \ub370 \uc758\uc874\ud588\ub2e4\uba74, \uc774\ub4e4\uc758 \uc5f0\uad6c\ub294 \uc784\uc0c1 \uc2b9\uc778\uc744 \ubc1b\uc740 \uc720\uc804\uc790 \uce58\ub8cc \ubc29\uc2dd\uc778 \uc6a9\ub3c4 \ubcc0\uacbd\ub41c \ubc14\uc774\ub7ec\uc2a4\ub97c \uc0ac\uc6a9\ud558\uc5ec \ub3d9\ubb3c\uc758 \uc138\ud3ec\uc5d0 \uc778\uc790\ub97c \uc804\ub2ec\ud588\ub2e4.<\/p>\n \ud55c\ud3b8 \uc9c0\ub09c 1\uc6d4 12\uc77c \uad6d\uc81c\ud559\uc220\uc9c0 ‘\uc140’\uc5d0\ub294 \uc774\ubc88 \uc5f0\uad6c\ud300\uacfc \ube44\uc2b7\ud55c \uc811\uadfc \ubc29\uc2dd\uc73c\ub85c \ub299\uc740 \uc0dd\uc950\uc758 \uc783\uc740 \uc2dc\ub825\uc744 \ub418\ucc3e\uc740 \ubbf8\uad6d \ud558\ubc84\ub4dc\ub300 \uc758\ub300 \ub370\uc774\ube44\ub4dc \uc2f1\ud06c\ub808\uc5b4 \uad50\uc218\ud300\uc758 \uc5f0\uad6c \uacb0\uacfc\uac00 \ubc1c\ud45c\ub410\ub2e4. \uc5f0\uad6c\ud300\uc740 \ud6c4\uc131\uc720\uc804\ud559\uc774\ub77c\ub294 \ubd80\ubd84\uc5d0 \ucd08\uc810\uc744 \ub9de\ucdb0 \uc5f0\uad6c\ub97c \uc9c4\ud589\ud588\ub2e4. \ud6c4\uc131\uc720\uc804\ud559\uc740 \uc5fc\uae30\uc11c\uc5f4 \uc774\uc678\uc5d0\u00a0DNA<\/span>\uc5d0 \uc77c\uc5b4\ub098\ub294 \ubd80\ubd84\uc801\uc778 \ubcc0\ud654\ub97c \uc5f0\uad6c\ud558\ub294 \ud559\ubb38\uc774\ub2e4. \uc5fc\uae30\uc11c\uc5f4\uc5d0\ub294 \ubcc0\ud654\ub97c \uc8fc\uc9c0 \uc54a\uace0\ub3c4 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud560 \uc218 \uc788\ub2e4\ub294, \uc989 \uc720\uc804\uccb4 \ubc1c\ud604\uc744 \ucf1c\uace0 \ub04c \uc218 \uc788\ub2e4\ub294 \uac1c\ub150\uc774\ub2e4.<\/p>\n \uc5f0\uad6c\ud300\uc740 \ud6a8\uc18c \uc720\uc804\uc790\ub97c \uc8fc\uc785\ud574 5\uac1c\uc6d4 \ub41c \uc5b4\ub9b0 \uc0dd\uc950\uc758\u00a0DNA<\/span>\ub97c \uc808\ub2e8\ud588\ub2e4.\u00a0DNA<\/span>\uc758 \uc774\uc911\ub098\uc120\uc774 \ub04a\uae34 \ubcc0\uc774 \uc0dd\uc950\ub294 \uc774\ud6c4 \uba87 \uc8fc \ub9cc\uc5d0 16\uac1c\uc6d4\uc758 \uc911\ub144 \uc0dd\uc950\ucc98\ub7fc \ub098\uc774\uac00 \ub4e4\uc5b4\ubc84\ub838\ub2e4. \ub1cc, \ub208, \uadfc\uc721, \ud53c\ubd80, \uc2e0\uc7a5 \uc870\uc9c1 \ub4f1\ub3c4 \ubaa8\ub450 \ub178\ud654\ub418\uc5c8\ub2e4. \uc774\ub54c \uc57c\ub9c8\ub098\uce74 \uad50\uc218\uac00 \uc0ac\uc6a9\ud588\ub358 \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \uc720\uc804\uc790 \uc911 3\uac1c(Oct4<\/span>,\u00a0Sox2<\/span>,\u00a0Klf4<\/span>)\ub97c \ub299\uc5b4\ubc84\ub9b0 \uc0dd\uc950\uc5d0 \uc8fc\uc785\ud588\ub2e4. \uc720\uc804\uc790 \uc815\ubcf4\ub97c \uc77d\uc5b4\ub4e4\uc600\ub358 \uc80a\uc740 \uc138\ud3ec\uc758 \ub2a5\ub825\uc744 \ubcf5\uc6d0\ud558\uae30 \uc704\ud574 \uc2a4\uc704\uce58\ub97c \uc7ac\ubd80\ud305\ud55c \uac83\uc774\ub2e4. \uc2e4\ud5d8 \uacb0\uacfc \uc0dd\uc950\ub294 \uc2dc\ub825\uacfc \ub1cc, \uadfc\uc721, \uc2e0\uc7a5 \uc138\ud3ec \ubaa8\ub450 \ud68c\ubcf5\ub418\uc5c8\ub2e4. \uc0dd\uc950\uc758 \ub098\uc774\ub3c4 5\uac1c\uc6d4\uc774\ub358 \uc0c1\ud0dc\ub85c \ub2e4\uc2dc \uc80a\uc5b4\uc84c\ub2e4.<\/p>\n \uc5f0\uad6c\ud300\uc740 \ub610 \uac19\uc740 \ubc29\ubc95\uc73c\ub85c 80\uc138\uc5d0 \ud574\ub2f9\ud558\ub294 \uc0dd\uc950\uc758 \uc218\uba85\uc744 \uc5f0\uc7a5\ud558\ub294 \ub370\ub3c4 \uc131\uacf5\ud588\ub2e4. \ud6c4\uc131\uc720\uc804\uccb4\ub97c \uc870\uc808\ud574 \ub178\ud654\ub97c \uc55e\ub2f9\uae30\uac70\ub098 \uc80a\uc5b4\uc9c0\uac8c \ud560 \uc218\ub3c4 \uc788\uc74c\uc744 \uc99d\uba85\ud55c \uac83\uc774\ub2e4.<\/p>\n<\/div>\n<\/div>\n<\/div>\n <\/p>\n <\/p>\n <\/p>\n \uc544\ub798\ub294 2023\ub144 1\uc6d4 27\uc77c \ub274\uc2a4\uc785\ub2c8\ub2e4~<\/p>\n (\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n <\/p>\n <\/p>\n \ud53c\uc5d0 \ub300\ud55c \uc18d\uc124\uc740 \uc5ed\uc0ac\uac00 \uc624\ub798\ub410\ub2e4. \uc6d0\uc2dc \uc778\ub958\ub294 \ud53c\ub97c \ub9ce\uc774 \ud758\ub9ac\uba74 \uc8fd\uc5b4\uac00\ub294 \ub3d9\ub8cc\uc640 \uc8fc\ubcc0 \ub3d9\ubb3c\uc744 \ubcf4\uba74\uc11c \ud53c \uc18d\uc5d0 \uc0dd\uba85\ub825\uc774 \uc788\ub2e4\uace0 \uc0dd\uac01\ud558\uae30 \uc2dc\uc791\ud588\uc744 \uac83\uc774\ub2e4. \ud53c\uc5d0 \ub300\ud55c \uc778\ub958\uc758 \uc0dd\uac01\uc744 \uc5ff\ubcfc \uc218 \uc788\ub294 \uc624\ub798\ub41c \uae30\ub85d\uc740 \uc131\uacbd\uc5d0\uc11c \ud53c\ub97c \ub9c8\uc2dc\uc9c0 \ubabb\ud558\uac8c \ud558\ub294 \uacc4\uc728\uc744 \uae30\ub85d\ud558\uac70\ub098 \ucd5c\ud6c4\uc758 \ub9cc\ucc2c \ub3d9\uc548 \uc608\uc218\uac00 \uc81c\uc790\ub4e4\uc5d0\uac8c \ud3ec\ub3c4\uc8fc\ub97c \uac74\ub0b4\uba70 \u2018\uc774\uac83\uc740 \ub098\uc758 \ud53c\u2019\ub77c\uace0 \ud558\ub294 \uc7a5\uba74\uc744 \ub4e4 \uc218 \uc788\ub2e4. \uc6b0\ub9ac\ub098\ub77c\uc5d0\uc11c\ub3c4 \uc61b \ubbfc\uac04\uc694\ubc95 \uc911 \ud558\ub098\ub85c \uc8fd\uc5b4\uac00\ub294 \uc0ac\ub78c\uc744 \uc0b4\ub9ac\ub294 \ubc29\ubc95\uc73c\ub85c \uc190\uac00\ub77d\uc744 \ub04a\uc5b4 \ud53c\ub97c \uba39\uc774\ub294 \uac83\uc774 \uc788\uc5c8\ub2e4.<\/p>\n \uc774\ub7ec\ud55c \uc0dd\uac01\ub4e4\uc744 \ud655\uc7a5\ud558\uba74 \uac74\uac15\ud55c \ub3d9\ubb3c\uacfc \uc0ac\ub78c\uc758 \ud608\uc561\uc5d0\ub294 \uc80a\uc74c\uacfc \uc0dd\uae30\ub97c \uc720\uc9c0\ud558\ub294 \ubb34\uc5c7\uc778\uac00\u00a0\ub2f4\uaca8\uc838 \uc788\ub2e4\uace0 \uc0c1\uc0c1\ud558\uae30 \uc27d\ub2e4. \uadf8\ub798\uc11c \uc5b4\ub9ac\uace0 \uac74\uac15\ud55c \ub3d9\ubb3c\uacfc \uc0ac\ub78c\uc758 \ud608\uc561\uc744 \ub9c8\uc2dc\uac70\ub098 \uc218\ud608 \ubc1b\uc73c\uba74 \ub299\uac70\ub098 \ubcd1\ub4e0 \uc0ac\ub78c\uc774 \ub2e4\uc2dc \uc80a\uc74c\uacfc \uc0dd\uae30\ub97c \ub418\ucc3e\uc744 \uc218 \uc788\ub2e4\ub294 \ubbff\uc74c\uc774 \uc624\ub7ab\ub3d9\uc548 \uc788\uc5c8\ub358 \uac83 \uac19\ub2e4. \ud48d\ubb38\uc5d0 \uc758\ud558\uba74 1492\ub144 \ub85c\ub9c8 \uad50\ud669 \uc778\ub178\uccb8\uc2dc\uc624 8\uc138\uac00 \ub9d0\ub144\uc5d0 \uac74\uac15\uc744 \ud68c\ubcf5\ud558\uae30 \uc704\ud574 \uc18c\ub144\uc758 \ud53c\ub97c \ub9c8\uc2dc\ub77c\ub294 \uc758\uc0ac\uc758 \ucc98\ubc29\uc744 \ubc1b\uc558\ub2e4\uace0 \ud558\ub294\ub370, \ud53c\ub97c \uc0dd\uba85\ub825\uc758 \uc6d0\ucc9c\uc774\ub77c \uc0dd\uac01\ud55c \uc624\ub79c \uc5ed\uc0ac\ub97c \uc0dd\uac01\ud574\ubcf4\uba74 \uae30\ub85d\ub418\uc9c0 \uc54a\uc740 \uc0ac\ub840\ub4e4\uc740 \ud6e8\uc52c \ub9ce\uc744 \uac83\uc73c\ub85c \ucd94\uce21\ub41c\ub2e4.<\/p>\n \uc0ac\uc2e4 \ud608\uc561\uc774 \uc0dd\uba85\ub825\uc744 \ub2f4\uace0 \uc788\ub2e4\ub294 \uc0dd\uac01\uc740 \uacfc\ud559\uc801\uc73c\ub85c \uc544\uc8fc \ud2c0\ub9b0 \ub9d0\uc740 \uc544\ub2c8\ub2e4. \uc65c\ub0d0\ud558\uba74 \ud604\ub300\uc778\ub4e4\ub3c4 \uc6d0\uc2dc\uc778\ub4e4\ucc98\ub7fc \ud608\uc561\uc774 \ubd80\uc871\ud558\uba74 \uc8fd\uc74c\uc744 \ub9de\uace0 \uc218\ud608\uc744 \ud1b5\ud574 \ubcf4\ucda9\ud558\uba74 \uc0dd\uba85\uc744 \ub418\ucc3e\ub294 \uc6d0\ub9ac\ub97c \uc27d\uac8c \uc774\ud574\ud558\uace0 \uc788\uc73c\uba70, \uc2e4\uc81c\ub85c \uc774\ub7ec\ud55c \uc2dc\ub3c4\uac00 \uc778\uac04\uc758 \uc0dd\uba85\uc744 \ub418\uc0b4\ub9ac\ub294\ub370 \ud6a8\uacfc\uc801\uc784\uc744 \uc54c\uace0 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4. \uadf8\ub798\uc11c 1665\ub144 \uc601\uad6d\u00a0\uc758\uc0ac\uc778 \ub9ac\ucc28\ub4dc \ub85c\uc6cc(Richard Lower)\uac00 \ub3d9\ubb3c\ub4e4\uc744 \ub300\uc0c1\uc73c\ub85c \ud558\ub098\uc758 \uac1c\uccb4\uac00 \ub2e4\ub978 \uac1c\uccb4\ub85c\ubd80\ud130 \ud53c\ub97c \uc804\ub2ec\ubc1b\uc744 \uc218 \uc788\uc74c\uc744 \uc99d\uba85\ud558\ub824 \ud588\uace0, 1818\ub144 \uc601\uad6d\uc758 \uc0b0\ubd80\uc778\uacfc \uc758\uc0ac\uc778 \uc81c\uc784\uc2a4 \ube14\ub7f0\ub378(James Blundell)\uc740 \ud608\uc561\uc774 \ubd80\uc871\ud574 \uc8fd\uc5b4\uac00\ub294 \uc0b0\ubaa8\uac00 \uac74\uac15\ud55c \uac00\uc871\uc758 \ud608\uc561\uc744 \uc218\ud608\ubc1b\uc744 \uc218 \uc788\ub3c4\ub85d \ud574 \uc0b0\ubaa8\uac00\u00a0\uc0dd\uba85\uc744 \ub2e4\uc2dc \ucc3e\uc744 \uc218 \uc788\uc5c8\ub2e4.<\/p>\n <\/p>\n \ud504\ub791\uc2a4 \uc0dd\ub9ac\ud559\uc790 \ud3f4 \ubca0\ub974\ud2b8(Paul Bert)\ub294 1860\ub144\ub300\uc5d0 \uc7a5\uae30 \uc774\uc2dd\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub97c \ubaa9\uc801\uc73c\ub85c \ud770 \uc950 \ub450 \ub9c8\ub9ac\uc758 \ud53c\ubd80\ub97c \uc11c\ub85c \uc811\ud569\ud574 \ub450 \uac1c\uccb4\uac00 \ud558\ub098\ub85c \ud569\uccd0\uc9c4 \ubaa8\uc2b5\uc758 \u2018\ud30c\ub77c\ubc14\uc774\uc624\uc2dc\uc2a4(parabiosis)\u2019\ub97c \ucc98\uc74c\uc73c\ub85c \uc120\ubcf4\uc600\ub2e4. \uc811\ud569\ub41c \ud53c\ubd80\ub97c \ud1b5\ud574 \ud608\uad00\uc774 \uc774\uc5b4\uc9d0\uc73c\ub85c\uc368 \ub450 \uc950\ub294 \ud558\ub098\uc758 \uc21c\ud658\uacc4\ub97c \uc774\ub8f0 \uc218 \uc788\uc5c8\uc73c\ubbc0\ub85c \uc774\ub294 \uc11c\ub85c \ub2e4\ub978 \ub450 \uac1c\uccb4\uac00 \uc0c1\ub300\ubc29\uc5d0\uac8c \uc9c0\uc18d\uc801\uc73c\ub85c \uc790\uc2e0\uc758 \ud53c\ub97c \uc218\ud608\ud558\ub294 \uac83\uacfc \uac19\uc740 \uac83\uc774\uc5c8\ub2e4.<\/p>\n \uadf8 \ub4a4 \uc774 \uae30\ubc95\uc740 \ud608\uad00\uc744 \uc9c1\uc811 \uc5f0\uacb0\ud558\ub294 \uc2dd\uc73c\ub85c \ubc1c\uc804\ud558\uac8c \ub418\uc5c8\uace0, 1972\ub144 \uce98\ub9ac\ud3ec\ub2c8\uc544\uc8fc\ub9bd\ub300 \ud504\ub808\ub370\ub9ad \ub8e8\ub4dc\uc705(Frederic C. Ludwig)\uacfc \ub85c\ubc84\ud2b8 \uc5d8\uc1fc\ud504(Robert M. Elshoff)\ub294 \uc774 \uae30\ubc95\uc744 \ud65c\uc6a9\ud574 \uc80a\uc740 \uc950\uc758 \ud53c\uac00 \ub299\uc740 \uc950\uc5d0\uac8c \uc9c0\uc18d\uc801\uc73c\ub85c \uc804\ub2ec\ub418\uac8c \ud558\uc600\ub354\ub2c8 \ub299\uc740 \uc950\uc758 \uc218\uba85\uc774 \uc5f0\uc7a5\ub418\uc5c8\ub2e4\ub294 \ud765\ubbf8\ub85c\uc6b4 \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc1c\ud45c\ud55c \uc801\uc774 \uc788\uc5c8\ub2e4(10.1111\/j.2164-0947.1972.tb02712.x).<\/p>\n \uadf8 \ud6c4 \ub9ce\uc740 \uc5f0\uad6c\uc790\ub4e4\uc774 \u2018\uc80a\uc74c\uc758 \ud53c\u2019\uac00 \ub178\ub144\uc758 \ub3d9\ubb3c\uc5d0\uac8c \uc2e0\uccb4\uc801 \uc80a\uc74c\uc744 \uac00\uc838\ub2e4 \uc904 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c\uc5d0 \ub6f0\uc5b4\ub4e4\uc5c8\ub2e4. 2005\ub144 \ubbf8\uad6d \uc2a4\ud0e0\ud37c\ub4dc\ub300\uc758 \ud1a0\ub9c8\uc2a4 \ub79c\ub3c4(Thomas A Rando) \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \ud30c\ub77c\ubc14\uc774\uc624\uc2dc\uc2a4\ub97c \ud1b5\ud574 \uc80a\uc740 \ud53c\ub97c \uc218\ud608\ubc1b\uc740 \ub299\uc740 \uc950\ub294 \uc5ec\ub7ec \uc870\uc9c1 \ub0b4 \uc138\ud3ec\ub4e4\uc758 \uc7ac\uc0dd \ubc0f \ubd84\uc5f4\uc774 \ub2e4\uc2dc \uc99d\uac00\ud558\ub294 \ub4f1 \uc80a\uc740 \uc0dd\uc950\uc758 \uc870\uc9c1\uacfc \ube44\uc2b7\ud55c \uc0dd\ubb3c\ud559\uc801 \ubcc0\ud654\uac00 \uc77c\uc5b4\ub0a8\uc744 \ubcf4\uace0\ud588\ub2e4(doi.org\/10.1038\/nature03260). \uc774\ub294 \uc80a\uc740 \uac1c\uccb4\uc758 \ud608\uc561 \ub0b4 \ubb34\uc5c7\uc778\uac00\uac00 \ub178\ud654\uc758 \uc5ed\uc804\uc744 \uc774\ub8f0 \uc218 \uc788\ub294 \uc0dd\ubb3c\ud559\uc801 \uc815\uccb4\uac00 \uc874\uc7ac\ud55c\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud55c\ub2e4.<\/p>\n \uadf8\ub807\ub2e4\uba74 \u2018\ub178\ud654\uc758 \ud53c\u2019\ub294 \uc815 \ubc18\ub300\ub85c \uc80a\uc74c\uc744 \uc5ed\uc804\uc2dc\ud0a4\ub294 \ubb34\uc5c7\uc778\uac00\ub97c \ub2f4\uace0 \uc788\ub2e4\uace0 \uc0dd\uac01\ud560 \uc218\ub3c4 \uc788\uc9c0 \uc54a\uc744\uae4c.\u00a0\ub098\uc774\ub4e0 \ub3d9\ubb3c\uc758 \ud53c\ub97c \uc5b4\ub9b0 \ub3d9\ubb3c\uc5d0\uac8c \uc218\ud608\ud558\uba74 \uc624\ud788\ub824 \ub178\ud654\ub97c \uac00\uc18d\ud654 \uc2dc\ud0ac \uc218 \uc788\uc744\uae4c\ub77c\ub294 \uc810\uc774 \uad81\uae08\ud574\uc9c4\ub2e4.\u00a02022\ub144 \ubc84\ud074\ub9ac \uce98\ub9ac\ud3ec\ub2c8\uc544\ub300\u00a0\uc774\ub9ac\ub098 \ucf58\ubcf4\uc774 \uad50\uc218 \uc5f0\uad6c\ud300\uc774 \uad6d\uc81c\ud559\uc220\uc9c0 ‘\ub124\uc774\ucc98 \uba54\ud0c0\ubcfc\ub9ac\uc998(Nature Metabolism)\uc5d0 \ubc1c\ud45c(doi.org\/10.1038\/s42255-022-00609-6)\uc5d0\u00a0\ub299\uc740 \uc950\uc758 \ud53c\ub97c \uc218\ud608 \ubc1b\uc73c\uba74 \uc80a\uc740 \uc950\uc758 \uc138\ud3ec \ub178\ud654\uac00 \ucd09\uc9c4\ub418\uc5b4 \uc2e0\uccb4 \ub178\ud654\uac00 \uc804\uccb4\uc801\uc73c\ub85c \ube60\ub974\uac8c \uc9c4\ud589\ub41c\ub2e4\ub294 \uc5f0\uad6c\uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\ub2e4.<\/p>\n \uc774\ub7ec\ud55c \ud6a8\uacfc\ub294 \ub2e8\uc21c\ud788 \uc80a\uc740 \uc950\uc758 \ud53c\uac00 \ub299\uc740 \uc950\uc758 \ud53c\uc5d0 \uc758\ud574 \ud76c\uc11d\ub418\uc5b4 \u2018\uc80a\uc74c\u2019\uc758 \ud798\uc774 \ub5a8\uc5b4\uc9c4 \uac83\uc774 \uc544\ub2c8\ub77c, \ub299\uc740 \uc950\uc758 \ud53c \uc18d\uc5d0 \ub178\ud654\ub97c \ucd09\uc9c4\ud558\ub294 \ubb34\uc5c7\uc778\uac00\uac00 \uc874\uc7ac\ud558\uae30 \ub54c\ubb38\uc778\u00a0\uac83\uc73c\ub85c \ubcf4\uc778\ub2e4. \uc2e4\uc81c\ub85c \ucf58\ubcf4\uc774 \uad50\uc218 \uc5f0\uad6c\ud300\uc774 \ud56d\ub178\ud654\uc81c\uc758 \uc77c\uc885\uc73c\ub85c\uc11c \ub178\ud654 \uc138\ud3ec\ub4e4\uc744 \uc81c\uac70\ud558\ub294 \ud6a8\uacfc\uac00 \uc788\ub294 \uc138\ub180\ub9ac\ud2f1(senolytic) \uc57d\ubb3c\uc744 \ubbf8\ub9ac \ucc98\ub9ac\ud55c \ub299\uc740 \uc950\uc758 \ud53c\ub97c \uc80a\uc740 \uc950\uc5d0\uac8c \uc804\ub2ec\ud588\ub354\ub2c8 \uc218\ud608\uc5d0 \uc758\ud55c \uc80a\uc740 \uc950\uc758 \ub178\ud654 \ucd09\uc9c4 \ud604\uc0c1\uc774 \uc0ac\ub77c\uc84c\ub2e4. \uc774\ub7ec\ud55c \uc5ec\ub7ec \uc5f0\uad6c\uacb0\uacfc\ub4e4\uc744 \ud1b5\ud574 \uc54c \uc218 \uc788\ub294 \uc0ac\uc2e4\uc740\u00a0\ubab8 \uc18d \uc5b4\ub514\uc5d0\uc11c\uc778\uac00\ub294 \uc80a\uc74c\uacfc \ub178\ud654\ub97c \uc720\ub3c4\ud560 \uc218 \uc788\ub294 \ubb3c\uc9c8\ub4e4\uc744 \ubd84\ube44\ub418\uace0 \uc788\uc73c\uba70, \uc774\ub294 \ud608\uc561\uc744 \ud1b5\ud574 \uc628 \ubab8\uc744 \uc21c\ud658\ud558\uba70 \ub178\ud654\uc758 \uc18d\ub3c4\ub97c \uc870\uc808\ud558\uace0 \uc788\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n \uc774\uc81c \uacfc\ud559\uc790\ub4e4\uc758 \uad00\uc2ec\uc740 \uc80a\uc74c\uacfc \ub178\ud654\ub97c \uc870\uc808\ud558\ub294 \ud608\uc561 \uc18d \ubb3c\uc9c8\uc758 \uc815\uccb4\uc774\ub2e4. \ud2b9\ud788 \uc80a\uc740 \uac1c\uccb4\uc758 \ud608\uc561 \ub0b4 \ubb34\uc5c7\uc778\uac00\uac00 \uc2e4\uc81c\ub85c \uc138\ud3ec \ubc0f \uc720\uc804\uc790 \ubcc0\ud654\ub97c \ud1b5\ud574 \ub178\ud654\uc758 \uc5ed\uc804\uc744 \uc774\ub8f0 \uc218 \uc788\ub2e4\ub294 \uc99d\uac70\uac00 \uc313\uc774\uba74\uc11c \uc80a\uc740 \uc0ac\ub78c\uc758 \ud53c\uc5d0 \uc874\uc7ac\ud558\uba74\uc11c \ub178\ud654\ub97c \ub2a6\ucd94\uac70\ub098 \ubc29\uc9c0\ud560 \uc218 \uc788\ub294 \ud608\uc561 \ub0b4 \ubb3c\uc9c8\uc758 \uc815\uccb4\ub97c \ucc3e\uace0\uc790 \ub9ce\uc740 \uacfc\ud559\uc790\ub4e4\uc774 \uad00\uc2ec\uc744 \uae30\uc6b8\uc774\uace0 \uc788\ub2e4.<\/p>\n \ud608\uc561\uc740 \uc801\ud608\uad6c, \ubc31\ud608\uad6c, \ud608\uc18c\ud310 \ub4f1\uc758 \ud608\uad6c\ub4e4\uacfc \ub2e4\uc591\ud55c \ub2e8\ubc31\uc9c8\uacfc \ubb34\uae30\uc9c8, \ub300\uc0ac\uccb4 \ub4f1\uc774 \ud3ec\ud568\ub418\uc5b4 \uc788\ub294 \ud608\uc7a5(plasma)\uc73c\ub85c \uad6c\uc131\ub41c \uc561\uccb4\ub2e4. \uc774\ub4e4 \uc911 \uac00\uc7a5 \ud070 \uc8fc\ubaa9\uc744 \ubc1b\ub294 \ud608\uc561 \ub0b4 \uc131\ubd84\uc740 \u2018\ud608\uc7a5\u2019\uc774\ub2e4.\u00a0\ud608\uc7a5\uc744 \uad6c\uc131\ud558\ub294 \ubb3c\uc9c8\ub4e4\uc740 \ub2e4\uc591\ud55c \ub2e8\ubc31\uc9c8, \ub300\uc0ac\uccb4 \ub4f1\uc774\uba70 \uc774\ub4e4\uc758 \uc870\uc131\ub3c4\ub294 \uc2e0\uccb4 \uc0c1\ud0dc\ub098 \ub098\uc774 \ub4f1\uc5d0 \uc758\ud574 \ud06c\uac8c \ubc14\ub014 \uc218 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4.<\/p>\n \uc608\ub97c \ub4e4\uc5b4 \uc5d0\uc774\ubbf8 \uc640\uadf8\ub108\uc2a4(Amy J. Wagners) \ubbf8\uad6d \ud558\ubc84\ub4dc\ub300\u00a0\uad50\uc218 \uc5f0\uad6c\ud300\uc774 \uc80a\uc740 \uc950\uc758 \ud608\uc7a5\uc5d0 \uc874\uc7ac\ud558\ub294 \uc131\uc7a5\uc778\uc790 \uc911 \ud558\ub098\uc778 GDF11\uc774 \ub178\ud654\ub97c \ub2a6\ucd9c \uc218 \uc788\ub294 \u2018\uadf8\uac83\u2019\uc774\ub77c\uace0 \uc8fc\uc7a5\ud588\ub2e4(DOI: 10.1126\/science.125115). \ub2e4\ub978 \ud55c\ud3b8, \ud1a0\ub2c8 \uc640\uc774\uc2a4-\ucf54\ub808\uc774(Tony Wyss-Coray) \uc2a4\ud0e0\ud37c\ub4dc\ub300 \uad50\uc218 \uc5f0\uad6c\uc9c4\uc740 \uc80a\uc74c\uc758 \ud53c\ub97c \uc8fc\uc785\ubc1b\uc740 \ub299\uc740 \uc950\uc758 \ud68c\ucd98 \ud6a8\uacfc\uac00 \uc18c\uc218\uc758 \ub2e8\ubc31\uc9c8 \ubc0f \ud2b9\uc815 \uc870\uc9c1 \uc218\uc900\uc5d0\uc11c \ubc8c\uc5b4\uc9c0\ub294 \ud604\uc0c1\uc774 \uc544\ub2c8\ub77c \ub2e4\uc591\ud55c \uc885\ub958\uc758 \ubd84\uc790 \uae30\uc804 \ubc0f \uc138\ud3ec\ub4e4\uc758 \uc885\ud569\uc801\uc778 \uacb0\uacfc\ub77c\uace0 \uc608\uce21\ud588\ub2e4.<\/p>\n \uc774\uc5d0 \ub530\ub77c \ud30c\ub77c\ubc14\uc774\uc624\uc2dc\uc2a4\ub97c \ud1b5\ud574 \uc80a\uc740 \uc950\uc758 \ud53c\ub97c \uc218\ud608\ubc1b\uc740 \ub299\uc740 \uc950\uc758 20\uc5ec\uac1c \uc870\uc9c1\ub4e4 \ub0b4 \uc138\ud3ec\ub4e4\uc758 \uc720\uc804\uc790 \ubc1c\ud604 \ud328\ud134\uc744 \uc885\ud569 \ubd84\uc11d\ud55c \uacb0\uacfc(10.1038\/s41586-022-04461-2)\u00a0\uc9c0\ubc29\uc720\ub798\uc904\uae30\uc138\ud3ec(adipose mesenchymal stromal cell), \uc870\ud608\ubaa8\uc138\ud3ec(hematopoietic stem cell), \uac04\uc138\ud3ec (hepatocyte) \ub4f1\uc5d0\uc11c \uc720\uc804\uc790 \ubcc0\ud654\uac00 \uac00\uc7a5 \ub450\ub4dc\ub7ec\uc84c\ub2e4. \uac00\uc7a5 \ud070 \ubcc0\ud654\ub97c \ubcf4\uc778 \uc720\uc804\uc790\ub4e4\uc740 \uc8fc\ub85c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc804\uc790\uc804\ub2ec\uacc4(mitochondria electron transfer)\uc640 \uad00\ub828\ub418\uc5b4 \uc788\uc5c8\uc73c\uba70, \uc774\ub294\u00a0\uc8fc\ub85c ATP \uc0dd\uc131 \ub4f1 \uc138\ud3ec\ud638\ud761\uc5d0 \ud544\uc218\uc801\uc778 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\ub2e4.<\/p>\n \uadf8\ub807\ub2e4\uba74 \ub1cc\uc758 \ub178\ud654\ub3c4 \uc80a\uc740 \ud53c\uc758 \ub3c4\uc6c0\uc744 \ud1b5\ud574 \ub2a6\ucdb0\uc9c0\uac70\ub098 \uc5ed\uc804\ub420 \uc218 \uc788\uc744\uae4c.\u00a0\ub178\ud654\uac00 \uc9c4\ud589\ub428\uc5d0 \ub530\ub77c \uc2e0\uccb4\uc801\uc778 \ub2a5\ub825 \uc800\ud558\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc778\uc9c0\uae30\ub2a5\uc758 \uc800\ud558\ub97c \uccb4\uac10\ud558\ub294 \ubd84\ub4e4\uc774 \ub9ce\uc744\ud150\ub370, \ub1cc\uc758 \ub178\ud654\ub3c4 \uc80a\uc740 \ud53c\uc758 \ub3c4\uc6c0\uc744 \ubc1b\uc73c\uba74 \ub2f9\uc5f0\ud788 \ud68c\ubcf5\ub420 \uc218 \uc788\uc9c0 \uc54a\uc744\uae4c \ud558\ub294 \uae30\ub300\ub97c \ud560 \uc218\ub3c4 \uc788\ub2e4.<\/p>\n \ud558\uc9c0\ub9cc\u00a0\ub1cc\ub294 \ub2e4\ub978 \uc2e0\uccb4 \uc7a5\uae30\ub4e4\uacfc \ub2e4\ub974\uac8c \ud608\uc561\uc758 \uc601\ud5a5\uc744 \uc9c1\uc811 \ubc1b\uc9c0 \uc54a\ub294\ub2e4. \ud608\ub1cc\uc7a5\ubcbd(blood-brain barrier; BBB)\uc774\ub77c \ubd88\ub9ac\ub294 \ud2b9\uc218\ud55c \uad6c\uc870 \ub54c\ubb38\uc5d0 \ub1cc\uc138\ud3ec\ub294 \ud608\uc561\uc5d0 \uc9c1\uc811 \uc601\ud5a5\uc744 \ubc1b\uc744 \uc218 \uc5c6\uc73c\uba70 \ud608\ub1cc\uc7a5\ubcbd\uc744 \ud1b5\uacfc\ud560 \uc218 \uc788\ub294 \ud608\uc7a5 \ub0b4 \ud2b9\uc815 \ub2e8\ubc31\uc9c8 \ubc0f \ubb3c\uc9c8\ub4e4\ub9cc\uc774 \ub1cc\uc5d0 \uc9c1\uc811 \uc804\ub2ec\ub420 \uc218 \uc788\ub2e4.<\/p>\n <\/p>\n \ucd5c\uadfc \uba87 \ub144\uac04 \ub9ce\uc740 \uc5f0\uad6c\ub4e4\uc774 \uc80a\uc740 \ud53c\uc5d0\uc11c \uc5bb\uc5b4\ub0b8 \ud608\uc7a5\uc774 \ub1cc\uc758 \ub178\ud654\uc131 \ud1f4\ud589 \ubc0f \uc778\uc9c0\uae30\ub2a5 \uc800\ud558\ub97c \ub2a6\ucd98\ub2e4\uace0 \ubcf4\uace0\ud558\uace0 \uc788\ub2e4. \ud2b9\ud788 \ud608\uc7a5 \ub0b4 \ud3ec\ud568\ub41c \ub2e8\ubc31\uc9c8\ub4e4 \uc911 \ud608\ub1cc\uc7a5\ubcbd\uc744 \ud22c\uacfc\ud560 \uc218 \uc788\ub294 \ub2e8\ubc31\uc9c8\ub4e4\uc5d0 \ub300\ud55c \uad00\uc2ec\uc774 \ub192\uc740\ub370, \uadfc\uc721\uc5d0\uc11c \ubd84\ube44\ub418\ub294 ‘cathepsin B’, ‘irisin’ \ub4f1\uc740 \ud608\uc561\uc744 \ud1b5\ud574 \ud608\ub1cc\uc7a5\ubcbd\uc744 \ud1b5\uacfc\ud574 \ub1cc\ub85c \uc9c1\uc811 \uc804\ub2ec\ub418\uace0 \uc2e0\uacbd\uc601\uc591\uc778\uc790 \ubc1c\ud604 \ubc0f \uc2e0\uacbd\uc138\ud3ec \uc0dd\uc131 \uc99d\uac00\ub97c \uc720\ub3c4\ud560 \uc218 \uc788\ub2e4\uace0 \ubcf4\uace0\ub41c \ubc14\uac00 \uc788\ub2e4.<\/p>\n \ud765\ubbf8\ub86d\uac8c\ub3c4 \uc774\ub7ec\ud55c \ub2e8\ubc31\uc9c8\ub4e4 \uc911 \uc77c\ubd80\ub294 \uc2dd\uc2b5\uad00\uc774\ub098 \uc2e0\uccb4\ud65c\ub3d9(\uc6b4\ub3d9) \ubfd0\ub9cc \uc544\ub2c8\ub77c \ub178\ud654\uc5d0 \ub530\ub77c \ud608\uc7a5 \ub0b4 \ub18d\ub3c4\uac00 \ubcc0\ud558\ub294 \ub2e8\ubc31\uc9c8\ub4e4\uc774\uae30\ub3c4 \ud558\ub2e4. \uc608\ub97c \ub4e4\uc5b4 ‘\uc624\uc2a4\ud14c\uc624\uce7c\uc2e0(osteocalcin)’\uc774\ub77c \ubd88\ub9ac\ub294 \uace8\uc544\uc138\ud3ec(osteoblast)\uc5d0\uc11c \uc720\ub798\ud558\ub294 \ub2e8\ubc31\uc9c8\uc740 \ub098\uc774\uac00 \ub4e6\uc5d0 \ub530\ub77c \uc810\ucc28 \ud608\uc911 \ub18d\ub3c4\uac00 \uac10\uc18c\ud558\ub294 \ubc18\uba74, \uc6b4\ub3d9 \ub4f1\uacfc \uac19\uc740 \uc2e0\uccb4\ud65c\ub3d9\uc5d0 \uc758\ud574 \ub18d\ub3c4\uac00 \ub2e4\uc2dc \uc99d\uac00\ud558\ub294 \ud2b9\uc9d5\uc774 \uc788\ub2e4. \uadfc\uc721\uc5d0\uc11c \ubd84\ube44\ub418\ub294 \uc778\ud130\ub8e8\ud0a86(IL-6)\uc774 \uace8\uc544\uc138\ud3ec\uc5d0\uc11c \uc624\uc2a4\ud14c\uc624\uce7c\uc2e0\uc758 \ubd84\ube44\ub97c \uc720\ub3c4\ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc73c\uba70, \uc77c\ubd80\uc758 \uc624\uc2a4\ud14c\uc624\uce7c\uc2e0\uc740 \ub1cc\uae4c\uc9c0 \ub3c4\ub2ec\ud560 \uc218 \uc788\ub2e4. 2019\ub144 \ud504\ub791\uc2a4 \ud504\ub791\ud06c \uc624\ub9ac (Franck Oury) \ubc15\uc0ac \uc5f0\uad6c\uc9c4\uc740 \ud608\uc561 \ub0b4 \ud638\ub974\ubaac\uc774 \ub1cc\ub85c \uc804\ub2ec\ub418\uba74 \uc2e0\uacbd\uc601\uc591\uc778\uc790\uc758 \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ud0b4\uc73c\ub85c\uc368 \uae30\uc5b5 \ud5a5\uc0c1 \ubc0f \ub178\ud654\uc131 \uae30\uc5b5 \uac10\ud1f4\ub97c \ud68c\ubcf5\ud560 \uc218 \uc788\uc74c\uc744 \uc0dd\uc950\ubaa8\ub378\uc744 \ud65c\uc6a9\ud574\u00a0\uc99d\uba85\ud558\uae30\ub3c4 \ud588\ub2e4(10.1016\/j.cub.2018.12.021).<\/p>\n \ub178\ud654 \uc5ed\uc804\uc744 \uc704\ud574 \ud53c\ub97c \ud65c\uc6a9\ud558\uace0\uc790 \ud558\ub294 \uc5f0\uad6c\ub294 \uc544\uc9c1\ub3c4 \ud65c\ubc1c\ud788 \uc9c4\ud589 \uc911\uc774\uba70, \uc77c\ubd80\ub294 \uc778\uccb4\uc5d0 \ub3c4\uc6c0\uc774 \ub420 \uac83\uc774\ub77c\ub294 \uae30\ub300\uc5d0 \uc784\uc0c1\uc2e4\ud5d8\uc774 \uc9c4\ud589\ub418\uac70\ub098 \uc900\ube44\ub418\uace0 \uc788\ub2e4. \ubbf8\uad6d\uc5d0\uc11c\ub294 \ub098\uc774\uc5d0 \ub530\ub978 \ud608\uc7a5 \ub2e8\ubc31\uc9c8\uc758 \uc870\uc131 \ucc28\uc774\ub97c \ubd84\uc11d\ud558\uace0 \uc774\ub4e4 \uc911 \ub178\ud654\uc640 \uad00\ub828\ub41c \ub2e8\ubc31\uc9c8\ub4e4\uc744 \uad6c\uc131\ud574 \ub178\ud654 \uce58\ub8cc\uc81c\ub97c \uac1c\ubc1c\ud558\ub824\ub294 \ud68c\uc0ac\ub4e4(Ambrosia, Alkahest, Elevian \ub4f1)\uc774 \ucc3d\uc5c5\ud558\uae30\ub3c4 \ud588\ub2e4. \uc774\ub4e4\uc740 \ubaa8\ub450 \uc2e4\ud5d8\ub3d9\ubb3c\uc744 \ud1b5\ud574 \ubc1c\uacac\ud55c \uc5f0\uad6c\uacb0\uacfc\ub4e4\uc744 \uae30\ubc18\uc73c\ub85c \uac74\uac15\ud558\uace0 \uc80a\uc740 \uc0ac\ub78c\uc758 \ud608\uc7a5 \uc790\uccb4\ub97c \uc774\uc6a9\ud558\uac70\ub098 \uadf8 \ud608\uc7a5\ub4e4\uc5d0\uc11c \ub178\ud654 \ubc29\uc9c0 \ud6a8\uacfc\uac00 \uc788\uc5c8\ub358 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\ub4e4\uc744 \ud65c\uc6a9\ud574\u00a0\uc6b0\uc120 \ud1f4\ud589\uc131 \ub1cc\uc9c8\ud658\uc778 \uc54c\uce20\ud558\uc774\uba38,\u00a0\ud30c\ud0a8\uc2a8\ubcd1, \uad00\uc808\uc5fc \uce58\ub8cc\ub97c \ubaa8\uc0c9\uc911\uc774\ub2e4.<\/p>\n \ubb3c\ub860 \ub9ce\uc740 \ub3d9\ub8cc\uacfc\ud559\uc790\ub4e4\uacfc \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA) \ub4f1\uc758 \uacac\uc81c\uc640 \ube44\ub09c\uc774 \ub9cc\ub9cc\uce58 \uc54a\ub2e4. \uc80a\uc740 \ud53c\uc5d0\uc11c \ud655\ubcf4\ud55c \ud608\uc7a5 \uc131\ubd84\ub4e4\uc758 \ud56d\ub178\ud654 \ud6a8\uacfc \ubc0f \ub178\ud654\uc131 \uc9c8\ud658 \uce58\ub8cc \ud6a8\uacfc\uac00 \ubaa8\ub4e0 \uc5f0\uad6c\uc5d0\uc11c \uc7ac\ud604\ub418\uc9c0 \uc54a\ub294\ub2e4\ub294 \uc8fc\uc7a5\ub3c4 \uc788\uae30\ub3c4 \ud558\uace0 \ub2e4\ub978 \ud55c \ud3b8\uc5d0\uc11c\ub294 \ud608\uc7a5 \ub610\ub294 \ud608\uc7a5 \ub0b4 \ub2e8\ubc31\uc9c8\ub4e4\uc758 \ud6a8\uacfc\uac00 \uacfc\uc7a5\ub418\uc5c8\ub2e4\uace0 \uc9c0\uc801\ud558\uae30\ub3c4 \ud55c\ub2e4. FDA \ub4f1\uacfc \uac19\uc774 \uc758\uc57d\ud488 \ud5c8\uac00\ub97c \uc2ec\uc0ac\ud558\ub294 \uae30\uad00\uc740 \ub108\ubb34\ub098 \ub2f9\uc5f0\ud558\uac8c\ub3c4 \uc778\uccb4 \ubb3c\uc9c8\uc744 \uc784\uc0c1\uc5d0 \uc801\uc6a9\ud55c\ub2e4\ub294 \uc2dc\ub3c4\ub97c \ub9e4\uc6b0 \uc870\uc2ec\uc2a4\ub7ec\uc6b4 \uc2dc\uac01\uc73c\ub85c \ubc14\ub77c\ubcf4\uace0 \uc788\ub2e4. \uc774 \ubaa8\ub4e0 \ub09c\uad00\ub4e4\uc740 \uc544\uc9c1 \uc6b0\ub9ac\uac00 \ub178\ud654 \ubc0f \uc5ed\ub178\ud654\uc758 \ubd84\uc790 \uae30\uc804\uc744 \uc798 \ubaa8\ub974\uace0 \uc788\uae30 \ub54c\ubb38\uc5d0 \ubc1c\uc0dd\ud558\ub294 \ud55c\ubc14\ud0d5 \uc18c\ub3d9\uacfc \uac19\ub2e4\uace0 \ubcf8\ub2e4. \uadf8\ub798\uc11c, \uc9c0\uae08\uae4c\uc9c0\ub294 \uc778\ub958\uac00 \uc0dd\uba85\ub825\uc758 \uc815\uccb4\ub97c \ud608\uc561\uc5d0\uc11c \ucc3e\uae30 \uc704\ud574 \ub178\ub825\ud574\uc654\ub2e4\uba74, \uc774\uc81c\ubd80\ud130\ub294 \uaca8\uc6b0 \ucc3e\uc544\ub0b8 \uc0dd\uba85\ub825\uc758 \uc815\uccb4\ub97c \u2018\uc81c\ub300\ub85c\u2019 \uc0ac\uc6a9\ud558\uae30 \uc704\ud574 \ub2e4\uc2dc \ub178\ub825\ud560 \ub54c\uac00 \uc544\ub2cc\uac00 \uc2f6\ub2e4.<\/p>\n<\/section>\n<\/div>\n<\/div>\n <\/p>\n <\/p>\n <\/p>\n \uc544\ub798\ub294 2023\ub144 1\uc6d4 13\uc77c \ub274\uc2a4\uc785\ub2c8\ub2e4~<\/p>\n (\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n <\/p>\n “\ub299\uace0 \ub208\uba3c \uc950 \uc2dc\ub825 \ud68c\ubcf5\ud558\uace0 \uc80a\uc5b4\uc838\u2026\ub178\ud654\ub294 \uac00\uc5ed\uc801”<\/strong><\/p>\n <\/p>\n \ud558\ubc84\ub4dc\ub300 \uc758\ub300 \ube14\ub77c\ubc14\ud2b8\ub2c8\ud06c\uc5f0\uad6c\uc18c \ub370\uc774\ube44\ub4dc \uc2f1\ud074\ub808\uc5b4 \uad50\uc218\ud300\uc740 \uc774\ub0a0 \uacfc\ud559\uc800\ub110 ‘\uc140'(Cell)\uc5d0\uc11c \ub299\uace0 \ub208\uc774 \uba3c \uc950\uc758 \uc2dc\ub825\uc744 \ub418\ucc3e\uac8c \ud558\uace0 \ub1cc\ub97c \ub354 \uc80a\uac8c \ub9cc\ub4dc\ub294 \ud55c\ud3b8, \uadfc\uc721\uacfc \uc2e0\uc7a5 \uc870\uc9c1\uc744 \ub354\uc6b1 \uac74\uac15\ud558\uac8c \ud558\ub294 \ub4f1 \ud68c\ucd98\uc2dc\ud0a4\ub294 \ub370 \uc131\uacf5\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n \uc5f0\uad6c\ud300\uc740 \ub610 \uc774\uc640 \ubc18\ub300\ub85c \uc80a\uc740 \uc950\uc758 \ub178\ud654 \uc18d\ub3c4\ub97c \ub450 \ubc30\ub85c \ub192\uc5ec \uc2e0\uccb4\uc758 \uac70\uc758 \ubaa8\ub4e0 \uc870\uc9c1\uc5d0\uc11c \ud30c\uad34\uc801\uc778 \ub178\ud654\ud604\uc0c1\uc774 \ub098\ud0c0\ub098\uac8c \ud558\ub294 \ub370\ub3c4 \uc131\uacf5\ud588\ub2e4\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n \uc5f0\uad6c\ud300\uc740 \uc0dd\uc950 \uc138\ud3ec\uc758 \ub178\ud654\ub97c \ub418\ub3cc\ub9ac\uae30 \uc704\ud574 \uc77c\ubcf8 \uad50\ud1a0\ub300 \uc57c\ub9c8\ub098\uce74 \uc2e0\uc57c \uad50\uc218\uac00 \uc131\uccb4 \uc138\ud3ec\ub97c \ubc30\uc544\uc904\uae30\uc138\ud3ec \ub2e8\uacc4\ub85c \ub9cc\ub4e0 \uc5ed\ubd84\ud654\uc5d0 \uc0ac\uc6a9\ud588\ub358 4\uac00\uc9c0 ‘\uc57c\ub9c8\ub098\uce74 \uc804\uc0ac\uc778\uc790'(Oct3\/4, Sox2, Klf4, c-Myc) \uc911 3\uac00\uc9c0\ub97c \ud63c\ud569\ud55c \uce75\ud14c\uc77c\uc744 \uc0ac\uc6a9\ud588\ub2e4.<\/p>\n \ub208\uba3c \uc0dd\uc950\uc758 \uc190\uc0c1\ub41c \ub9dd\ub9c9 \uc2e0\uacbd\uc808\uacfc \ub178\ud654\ub41c \ub1cc, \uadfc\uc721, \uc2e0\uc7a5 \uc138\ud3ec\uc5d0 \uc57c\ub9c8\ub098\uce74 \uc804\uc0ac\uc778\uc790 \uce75\ud14c\uc77c\uc744 \ud22c\uc5ec\ud558\uace0 \ud56d\uc0dd\uc81c\ub85c \uc774\ub4e4 \uc778\uc790\ub97c \uc791\ub3d9\uc2dc\ud0a4\uc790 \uc950\uac00 \uc2dc\ub825\uc744 \uac70\uc758 \ub418\ucc3e\uc558\uace0 \ub1cc\u00b7\uadfc\uc721\u00b7\uc2e0\uc7a5 \uc138\ud3ec\ub3c4 \uc80a\uc740 \uc0c1\ud0dc\ub85c \ud68c\ubcf5\ub41c \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4.<\/p>\n \ub610 \ubc18\ub300\ub85c \ud6c4\uc0dd\uc720\uc804\uc790\ub97c \ubcc0\ud654\uc2dc\ud0a4\ub294 \ubc29\ubc95\uc744 \uac1c\ubc1c, \uc950\uc758 DNA\uc5d0 \ub3cc\uc5f0\ubcc0\uc774\ub97c \uc77c\uc73c\ud0a4\uc9c0 \uc54a\uc73c\uba74\uc11c DNA\uac00 \uc811\ud788\ub294 \ubc29\uc2dd\ub9cc \ubcc0\ud654\uc2dc\ucf1c \ub178\ud654\uac00 \ub450 \ubc30 \ube60\ub974\uac8c \uc9c4\ud589\ub418\ub3c4\ub85d \ud588\ub2e4.<\/p>\n \uc2f1\ud074\ub808\uc5b4 \uad50\uc218\ub294 “\uc774 \uc2e4\ud5d8\uc740 \ub178\ud654\uac00 \ub9c8\uc74c\ub300\ub85c, \uadf8\ub9ac\uace0 \uc55e\ub4a4\ub85c \uc77c\uc5b4\ub098\uac8c \ud560 \uc218 \uc788\ub294 \uac00\uc5ed\uc801 \uacfc\uc815\uc774\ub77c\ub294 \uac83\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uac83”\uc774\ub77c\uba70 “\uc6b0\ub9ac \ubab8\uc5d0\ub294 \ub178\ud654\ub97c \ub418\ub3cc\ub9b4 \uc218 \uc788\ub294 ‘\uc80a\uc74c\uc758 \ubc31\uc5c5 \uc0ac\ubcf8’\uc774 \uc788\ub2e4”\uace0 \ub9d0\ud588\ub2e4.<\/p>\n \uc774\uc5b4 \uc774 \uc2e4\ud5d8\uc740 \ub178\ud654\uac00 DNA\ub97c \ud6fc\uc190\ud558\uace0 \uc138\ud3ec\uc870\uc9c1\uc744 \uc190\uc0c1\ud574 \uc9c8\ubcd1\uacfc \uc0ac\ub9dd\uc5d0 \uc774\ub974\uac8c \ud558\ub294 \uc720\uc804\uc801 \ub3cc\uc5f0\ubcc0\uc774\uc758 \uacb0\uacfc\ub77c\ub294 \uacfc\ud559\uc801 \ubbff\uc74c\uc5d0 \ub3c4\uc804\ud558\ub294 \uac83\uc774\ub77c\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n \uadf8\ub294 \ub610 “\ub178\ud654\ub294 \uc720\uc804\uc801 \ub3cc\uc5f0\ubcc0\uc774\ub85c \uc0dd\uae34 \uc4f0\ub808\uae30(junk)\ub098 \uc190\uc0c1\uc5d0 \uc758\ud55c \uac8c \uc544\ub2c8\ub77c \uc624\ub798\ub41c \ucef4\ud4e8\ud130\uc5d0\uc11c \uc18c\ud504\ud2b8\uc6e8\uc5b4 \uc624\ub958\uac00 \ubc1c\uc0dd\ud558\ub294 \uac83\ucc98\ub7fc \uc138\ud3ec\uac00 DNA\ub97c \uc77d\uc5b4\ub0b4\ub294 \ub2a5\ub825\uc744 \uc783\uc5b4 \uae30\ub2a5\uc744 \uc0c1\uc2e4\ud558\ub294 \uac8c \uc6d0\uc778”\uc774\ub77c\uba70 \uc774\ub97c ‘\ub178\ud654\uc758 \uc815\ubcf4 \uc774\ub860’\uc774\ub77c\uace0 \uce6d\ud588\ub2e4.<\/p>\n \uc5f0\uad6c\ud300\uc740 \ub178\ud654\ub97c \uc774\ub7f0 \ud6c4\uc0dd\uc720\uc804\uc790\uac00 \uc720\uc804\uc790 \uc791\ub3d9\uc744 \uc870\uc808\ud558\ub294 \uacfc\uc815\uc5d0\uc11c \ub098\ud0c0\ub098\ub294 \ud604\uc0c1\uc774\ub77c\uace0 \uc124\uba85\ud588\ub2e4. \uc720\uc804\uc790\uc5d0 \ubd99\uc5b4\uc788\ub294 \ub2e8\ubc31\uc9c8\uc774\ub098 \ud654\ud559\ubb3c\uc9c8\uc778 \ud6c4\uc0dd\uc720\uc804\uc790\uac00 \uc2a4\uc704\uce58\ucc98\ub7fc \uc720\uc804\uc790 \uc791\ub3d9 \uc5ec\ubd80\ub97c \uc9c0\uc2dc\ud558\ub294\ub370, \uc5ec\uae30\uc5d0 \ubb38\uc81c\uac00 \uc0dd\uae30\uba74 DNA \uc190\uc0c1 \ub4f1 \ub178\ud654\uac00 \uc9c4\ud589\ub41c\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n \uc2f1\ud074\ub808\uc5b4 \uad50\uc218\ub294 “\uc774 \uc5f0\uad6c\uc758 \ub180\ub77c\uc6b4 \ubc1c\uacac\uc740 \uc778\uccb4\uc5d0 \ubcf8\uccb4\ub97c \ub9ac\uc14b\ud560 \uc218 \uc788\ub294 \uc18c\ud504\ud2b8\uc6e8\uc5b4 \ubc31\uc5c5 \uce74\ud53c\uac00 \uc788\ub2e4\ub294 \uac83\uc744 \ubc1d\ud78c \uac83”\uc774\ub77c\uba70 “\uc774\ub97c \ud1b5\ud574 \uc18c\ud504\ud2b8\uc6e8\uc5b4\uac00 \uc190\uc0c1\ub418\ub294 \uc774\uc720\uc640 \ub9ac\uc14b \uc2a4\uc704\uce58\ub97c \ub20c\ub7ec \ubcf8\uccb4\ub97c \uc7ac\ubd80\ud305 \ud568\uc73c\ub85c\uc368 \uc138\ud3ec\uac00 \uac8c\ub188\uc744 \ub2e4\uc2dc \uc81c\ub300\ub85c \uc77d\uc744 \uc218 \uc788\uac8c \ud558\ub294 \ubc29\ubc95\uc744 \ubc1d\ud600\ub0c8\ub2e4”\uace0 \ub9d0\ud588\ub2e4.<\/p>\n \uc774\uc5b4 “\ub178\ud654\ub97c \ub418\ub3cc\ub9ac\ub294 \ub370\uc5d0\ub294 50\uc0b4\uc9dc\ub9ac \ubab8\uc774\ub4e0 75\uc0b4\uc9dc\ub9ac \ubab8\uc774\ub4e0, \uac74\uac15\ud558\ub4e0 \ubcd1\ub4e4\uc5c8\ub4e0 \uc0c1\uad00\uc774 \uc5c6\ub2e4”\uba70 “\uc77c\ub2e8 \ud68c\ucd98 \uacfc\uc815\uc774 \uc2dc\uc791\ub418\uba74 \ubab8\uc740 \uc7ac\uc0dd\ud558\ub294 \ubc29\ubc95\uc744 \uae30\uc5b5\ud558\uace0 \ub299\uc5c8\ub4e0 \ubcd1\ub4e4\uc5c8\ub4e0 \uc0c1\uad00\uc5c6\uc774 \ub2e4\uc2dc \uc80a\uc5b4\uc9c8 \uac83”\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n \uadf8\ub294 “\ud68c\ucd98 \uc2a4\uc704\uce58\ub97c \ucc3e\ub294 \uc5f0\uad6c\ub294 \ub9e4\uc0ac\ucd94\uc138\uce20\uacf5\ub300(MIT) \ub300\ud559\uc6d0 \uc2dc\uc808 \ud638\ubaa8\uc5d0\uc11c \ub178\ud654 \uc870\uc808 \uc720\uc804\uc790\ub97c \ubc1c\uacac\ud558\uba74\uc11c \uc2dc\uc791\ub410\ub2e4”\uba70 “\uc774 \uc720\uc804\uc790\ub294 \ubaa8\ub4e0 \uc0dd\uba85\uccb4\uc5d0 \ubaa8\ub450 \uc874\uc7ac\ud558\uae30\uc5d0 \uc0ac\ub78c\uc5d0\uac8c\ub3c4 \ub611\uac19\uc774 \uc801\uc6a9\ud560 \uc218 \uc788\ub294 \ubc29\ubc95\uc774 \uc788\uc744 \uac83”\uc774\ub77c\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n<\/section>\n<\/div>\n<\/div>\n <\/p>\n <\/p>\n <\/p>\n \uc544\ub798\ub294 2023\ub144 2\uc6d4 9\uc77c \ub274\uc2a4\uc785\ub2c8\ub2e4~<\/p>\n![\"\"](\"https:\/\/imgnews.pstatic.net\/image\/081\/2019\/06\/04\/0003004159_002_20190604165110982.jpg?type=w647\")
<\/span><\/p>\n\ub299\uc740 \ud53c \uc8fc\uc785\ud588\ub354\ub2c8 \uc815\ub9d0\ub85c \ub299\uc5b4\ubc84\ub838\ub2e4\u2026\uc80a\uc740 \ud53c\ub294?<\/h2>\n<\/div>\n
\n\uc138\ud3ec \ubd84\ube44\ubb3c\uc774 \uc804\uc2e0 \ud37c\uc9c0\uba70 \ub178\ud654 \ucd09\uc9c4\ud55c \ub4ef
\n\ub299\uc740 \ud53c \ub178\ud654 \uc791\uc6a9, \uc80a\uc740 \ud53c \ud68c\ucd98 \ud6a8\uacfc\ubcf4\ub2e4 \ucee4<\/strong><\/div>\n![](\"https:\/\/imgnews.pstatic.net\/image\/028\/2022\/08\/11\/0002601963_001_20220812145701369.jpg?type=w647\")
<\/div>\n<\/div>\n![](\"https:\/\/imgnews.pstatic.net\/image\/028\/2022\/08\/11\/0002601963_002_20220812145701403.jpg?type=w647\")
<\/div>\n<\/div>\n![](\"https:\/\/imgnews.pstatic.net\/image\/028\/2022\/08\/11\/0002601963_003_20220812145701439.jpg?type=w647\")
<\/div>\n<\/div>\n\ub178\ud654\uc758 \uc5ed\uc804\u2026 \uc0dd\uc950 \ud68c\ucd98\uc2dc\ud0a8 \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d<\/h2>\n<\/div>\n
![](\"https:\/\/imgnews.pstatic.net\/image\/053\/2023\/01\/27\/0000034311_001_20230127180101130.gif?type=w647\")
<\/div>\n<\/div>\n![](\"https:\/\/imgnews.pstatic.net\/image\/053\/2023\/01\/27\/0000034311_002_20230127180101182.gif?type=w647\")
<\/div>\n<\/div>\n\uc80a\uc740 \ud53c \uc218\ud608\ubc1b\uc73c\uba74 \ud68c\ucd98\ud560 \uc218 \uc788\uc744\uae4c<\/h3>\n
![\"\uac8c\ud2f0\uc774\ubbf8\uc9c0\ubc45\ud06c](\"https:\/\/img1.daumcdn.net\/thumb\/R658x0.q70\/?fname=https:\/\/t1.daumcdn.net\/news\/202301\/27\/dongascience\/20230127125404539gxzd.jpg\")
<\/p>![\"\ud30c\ub77c\ubc14\uc774\uc624\uc2dc\uc2a4(parabiosis)\ub97c](\"https:\/\/img4.daumcdn.net\/thumb\/R658x0.q70\/?fname=https:\/\/t1.daumcdn.net\/news\/202301\/27\/dongascience\/20230127125406327gftm.jpg\")
<\/p>![\"\ud608\uc561](\"https:\/\/img2.daumcdn.net\/thumb\/R658x0.q70\/?fname=https:\/\/t1.daumcdn.net\/news\/202301\/27\/dongascience\/20230127125407539zcnf.jpg\")
<\/p>\ubbf8\uad6d \ub178\ud654 \uc5f0\uad6c\ud300, \uc2e4\ud5d8\uc2e4\uc11c \ub299\uc740 \uc0dd\uc950 ‘\ud68c\ucd98’ \uc131\uacf5<\/h3>\n
![\"\uc0dd\uc950](\"https:\/\/img1.daumcdn.net\/thumb\/R658x0.q70\/?fname=https:\/\/t1.daumcdn.net\/news\/202301\/13\/yonhap\/20230113171434444vhjh.jpg\")
<\/p>
![\"\ub178\ud654](\"https:\/\/img4.daumcdn.net\/thumb\/R658x0.q70\/?fname=https:\/\/t1.daumcdn.net\/news\/202302\/09\/dongascience\/20230209175424071hjls.jpg\")
<\/p>