\uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n <\/p>\n
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Abstract This review commemorates the 40th anniversary of DNA sequencing, a period in which we have already witnessed multiple technological revolutions and(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[33,34,29],"tags":[],"class_list":["post-3202","post","type-post","status-publish","format-standard","hentry","category-do-biology","category-lets-do-chemistry","category-lets-do-science"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":2672,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2672","url_meta":{"origin":3202,"position":0},"title":"CRISPR-Cas9-Based Genome Editing of Human Cells","author":"biochemistry","date":"February 15, 2019","format":false,"excerpt":"\u00a0 \u00a0 CRISPR\/Cas9 systems are engineered versions of the Cas9 protein and guide RNA. \u00a0Typically, they are identical to the\u00a0Streptococcus pyogenes\u00a0type II CRISPR systems, except that a single guide-RNA is used in place of the complementary crRNAs and tracrRNAs of the natural CRISPR system, and the Cas9 protein is codon-optimized\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"Genome Editing Overview2","src":"https:\/\/i0.wp.com\/sites.tufts.edu\/crispr\/files\/2014\/11\/Genome-Editing-Overview2-1024x667.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/sites.tufts.edu\/crispr\/files\/2014\/11\/Genome-Editing-Overview2-1024x667.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/sites.tufts.edu\/crispr\/files\/2014\/11\/Genome-Editing-Overview2-1024x667.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/sites.tufts.edu\/crispr\/files\/2014\/11\/Genome-Editing-Overview2-1024x667.png?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":4845,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=4845","url_meta":{"origin":3202,"position":1},"title":"CRISPR tool modifies genes precisely by copying RNA into the genome & CRISPR: the movie","author":"biochemistry","date":"November 15, 2019","format":false,"excerpt":"\u00a0 \u00a0 The ultimate goal of genome editing is to be able to make any specific change to the blueprint of life. A \u2018search-and-replace\u2019 method for genome editing takes us a giant leap closer to this ambitious goal. \u00a0 \u00a0 Variation in the DNA sequences that constitute the blueprint of\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3726,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3726","url_meta":{"origin":3202,"position":2},"title":"The human body is a mosaic of different genomes & Somatic mosaicism in normal tissues","author":"biochemistry","date":"June 8, 2019","format":false,"excerpt":"\u00a0 Survey finds that \u2018normal\u2019 human tissues are riddled with mutations. \u00a0 \u00a0 Skin has a high level of mosaicism compared to other tissues in the body.Credit: Science Photo Library \u00a0 \u00a0 The human body is a complex mosaic made up of clusters of cells with different genomes \u2014 and\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1857,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1857","url_meta":{"origin":3202,"position":3},"title":"CRISPR-Cas9 nuclease \uad00\ub828 \uba87 \uac00\uc9c0 \ub274\uc2a4","author":"biochemistry","date":"September 25, 2018","format":false,"excerpt":"\u00a0 \u00a0 CRISPR-Cas9\uacfc \uad00\ub828\ub41c \uba87 \uac00\uc9c0 \uc18c\uc2dd\uc785\ub2c8\ub2e4. (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) \u00a0 CRISPR tool puts RNA on the record \u00a0 The bacterial-defence system CRISPR\u2013Cas can store DNA snippets that correspond to encountered viral RNA sequences. One such system has now been harnessed to record gene expression over time in bacteria. \u00a0\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3891,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3891","url_meta":{"origin":3202,"position":4},"title":"Inserting DNA with CRISPR","author":"biochemistry","date":"July 16, 2019","format":false,"excerpt":"\u00a0 \u00a0 Most prokaryotes rely on the CRISPR-Cas system for adaptive immunity against viruses and mobile elements (1,\u00a02). Small RNAs produced from CRISPR direct Cas effector proteins to seek and destroy nucleic acids from invaders that have complementary target sites (3). There are multiple types of CRISPR, which are defined\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2647,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2647","url_meta":{"origin":3202,"position":5},"title":"Algae suggest eukaryotes get many gifts of bacteria DNA","author":"biochemistry","date":"February 8, 2019","format":false,"excerpt":"\u00a0 \u00a0 Algae found in thermal springs and other extreme environments have heated up a long-standing debate: Do eukaryotes\u2014organisms with a cell nucleus\u2014sometimes get an evolutionary boost in the form of genes transferred from bacteria? The genomes of some red algae, single-celled eukaryotes, suggest the answer is yes. 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