{"id":3047,"date":"2019-03-30T09:37:32","date_gmt":"2019-03-30T00:37:32","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=3047"},"modified":"2019-04-03T11:23:46","modified_gmt":"2019-04-03T02:23:46","slug":"%eb%82%98%ec%9d%b4-%eb%93%a4%ec%96%b4%eb%8f%84-%ec%83%88%eb%a1%9c%ec%9a%b4-%eb%87%8c%ec%84%b8%ed%8f%ac-%ec%83%9d%ec%84%b1%eb%90%9c%eb%8b%a4","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3047","title":{"rendered":"\ub098\uc774 \ub4e4\uc5b4\ub3c4 \u2018\uc0c8\ub85c\uc6b4 \ub1cc\uc138\ud3ec\u2019 \uc0dd\uc131\ub41c\ub2e4"},"content":{"rendered":"

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\ub098\uc774\uac00 \ub4e4\uba74 \ub1cc\uc138\ud3ec\uac00 \u2018\uc8fd\uae30\ub9cc\u2019 \ud55c\ub2e4\ub294 \uae30\uc874\uc758 \ud559\uc124\uc744 \ub4a4\uc9d1\ub294 \uc5f0\uad6c\uacb0\uacfc\uac00 \ub098\uc654\ub2e4.<\/p>\n

\ubbf8\uad6d \ub274\uc695 \uceec\ub7fc\ube44\uc544\ub300 \uc5f0\uad6c\uc9c4\uc5d0 \ub530\ub974\uba74 \uc6b0\ub9ac \ub1cc\ub294 \ub098\uc774\uac00 \ub4e0 \uc774\ud6c4\uc5d0\ub3c4 \uc9c0\uc18d\uc801\uc73c\ub85c \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc138\ud3ec\ub97c \ub9cc\ub4e4\uc5b4\ub0b4\ub294 \uac83\uc73c\ub85c \ubc1d\ud600\uc84c\ub2e4. \ud559\uacc4\uc5d0\uc11c\ub294 \uc77c\ubc18\uc801\uc73c\ub85c 13\uc138 \uc774\ud6c4\ubd80\ud130\ub294 \ub1cc\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uc138\ud3ec\uac00 \ub9cc\ub4e4\uc5b4\uc9c0\uc9c0 \uc54a\ub294\ub2e4\uace0 \uc5ec\uaca8\uc654\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uc5f0\uad6c\uc9c4\uc774 14~79\uc138 28\uba85\uc5d0\uac8c\uc11c \uae30\uc99d\ubc1b\uc740 \uc2dc\uc2e0\uc744 \uc774\uc6a9, \ub1cc \ud574\ub9c8\ub97c \uc790\uc138\ud788 \uad00\ucc30\ud55c \uacb0\uacfc, \uc131\uc778\uc758 \ub1cc\uc5d0\uc11c\ub3c4 \ub9c8\uce58 \uc5b4\ub9b0\uc774\ucc98\ub7fc \uc218 \ucc9c\uac1c\uc758 \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc138\ud3ec\uac00 \ub9cc\ub4e4\uc5b4\uc9c4 \uc0ac\uc2e4\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n

\uc774\ubc88 \uc5f0\uad6c\ub294 \uc9c0\ub09c\ub2ec 7\uc77c \ubbf8\uad6d \uce98\ub9ac\ud3ec\ub2c8\uc544\ub300\ud559 \uc2e0\ud504\ub780\uc2dc\uc2a4\ucf54\ucea0\ud37c\uc2a4 \uc5f0\uad6c\uc9c4\uc774 \uc138\uacc4\uc801\uc778 \uacfc\ud559\uc800\ub110 \u2018\ub124\uc774\ucc98\u2019\uc5d0 \uac8c\uc7ac\ud55c \uc5f0\uad6c\uacb0\uacfc\ub97c \uc644\uc804\ud788 \ub4a4\uc9d1\uc740 \uac83\uc774\uc5b4\uc11c \ub354\uc6b1 \ud559\uacc4\uc758 \uad00\uc2ec\uc774 \uc3e0\ub838\ub2e4.<\/p>\n

\ub2f9\uc2dc \uce98\ub9ac\ud3ec\ub2c8\uc544\ub300 \uc5f0\uad6c\uc9c4\uc740 \uae30\uc99d\ubc1b\uc740 \uc2dc\uc2e0 37\uad6c\uc758 \ub1cc\ub97c \ubd84\uc11d\ud55c \uacb0\uacfc, 13\uc138 \uc774\ud6c4\uc758 \ud574\ub9c8\uc5d0\uc11c\ub294 \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc138\ud3ec\uac00 \ubc1c\uacac\ub418\uc9c0 \uc54a\uc558\ub2e4\uace0 \ubc1c\ud45c\ud588\ub2e4. \uce98\ub9ac\ud3ec\ub2c8\uc544\ub300 \uc5f0\uad6c\uc9c4\uc740 \u201c\uc0c8\ub85c\uc6b4 \ub274\ub7f0\uc740 \ud0dc\uc544\uc640 \uac13\ub09c\uc544\uae30\uc5d0\uac8c\uc11c\ub294 \ub2e4\ub7c9 \ubc1c\uacac\ub410\uc9c0\ub9cc \uc774\ud6c4 \uae09\uaca9\ud788 \uc904\uc5b4\ub4e4\uc5c8\uace0, 18\uc138 \uc774\uc0c1\uc758 \ub1cc\uc5d0\uc11c\ub294 \uc804\ud600 \ubc1c\uacac\ub418\uc9c0 \uc54a\uc558\ub2e4\u201d\uace0 \ubc1d\ud78c \ubc14 \uc788\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uc5f0\uad6c\uacb0\uacfc\ub294 \ud559\uacc4\uc758 \ud070 \ud30c\ub780\uc774 \ub410\ub2e4. \uc138\uacc4 \uac01\uad6d \uc5f0\uad6c\uc9c4\uc740 \ub1cc\uc5d0\uc11c \uc0c8\ub86d\uac8c \ub9cc\ub4e4\uc5b4\uc9c0\ub294 \uac74\uac15\ud55c \ub1cc\uc138\ud3ec\ub97c \uc774\uc6a9\ud574 \uc54c\uce20\ud558\uc774\uba38\ub098 \uc6b0\uc6b8\uc99d \uac19\uc740 \ub1cc \uc9c8\ud658\uc744 \uce58\ub8cc\ud558\ub294 \ubc29\ubc95\uc744 \ucc3e\ub294\ub370 \ub178\ub825\ud574\uc654\ub2e4. \uce98\ub9ac\ud3ec\ub2c8\uc544\ub300 \uc5f0\uad6c\uc9c4\uc758 \uc5f0\uad6c\uacb0\uacfc\uac00 \uc0ac\uc2e4\uc774\ub77c\uba74, \uacfc\ud559\uc790\ub4e4\uc758 \ud604\uc7ac\uae4c\uc9c0\uc758 \ub178\ub825\uc774 \ud5db\uc77c\uc774 \ub420 \uc218\ub3c4 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uce98\ub9ac\ud3ec\ub2c8\uc544\ub300 \uc5f0\uad6c\uc9c4\uc758 \uc5f0\uad6c\uc5d0\ub294 \ud55c\uacc4\uac00 \uc788\uc5c8\ub2e4. \ub2f9\uc2dc \uc5f0\uad6c\uc5d0 \ud65c\uc6a9\ub41c \uae30\uc99d\ubc1b\uc740 \uc2dc\uc2e0 37\uad6c\ub294 \ubaa8\ub450 \uc0dd\uc804 \uc6b0\uc6b8\uc99d\uc774\ub098 \ub1cc\uc9c8\ud658 \ub4f1 \ud658\uc790\ub4e4\uc758 \uac83\uc774\uc5c8\uc73c\uba70, \ud22c\ubcd1\uc73c\ub85c \uc778\ud55c \uc2a4\ud2b8\ub808\uc2a4 \ub4f1\uc774 \ub1cc\uc138\ud3ec\ub97c \uc0c8\ub85c \ub9cc\ub4e4\uc5b4\ub0b4\ub294\ub370 \uc601\ud5a5\uc744 \ubbf8\ucce4\uc744 \uc218 \uc788\ub2e4\ub294 \uc9c0\uc801\uc774 \ub098\uc654\ub2e4.<\/p>\n

\ubc18\uba74 \uceec\ub7fc\ube44\uc544\ub300 \uc5f0\uad6c\uc9c4\uc758 \uc5f0\uad6c\uc5d0 \ud65c\uc6a9\ub41c \uc2dc\uc2e0 28\uad6c\ub294 \ubaa8\ub450 \uac74\uac15\ud55c \uc0c1\ud0dc\uc5d0\uc11c \uc0ac\uace0 \ub4f1\uc73c\ub85c \uac11\uc791\uc2a4\ub7fd\uac8c \uc0ac\ub9dd\ud55c \uc0ac\ub78c\ub4e4\uc758 \uac83\uc774\uc5c8\ub2e4. \uc774\ub4e4\uc758 \ub1cc\ub97c \ubd84\uc11d\ud55c \uacb0\uacfc \uc131\uc778\uc758 \ub1cc\uc5d0\uc11c\ub3c4 \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc138\ud3ec\uac00 \ub2e4\ub7c9\uc73c\ub85c \ub9cc\ub4e4\uc5b4\uc9c0\uace0 \uc788\uc74c\uc774 \ud655\uc778\ub410\ub2e4\ub294 \uac83\uc774 \uc5f0\uad6c\uc9c4\uc758 \uc124\uba85\uc774\ub2e4.<\/p>\n

\uc5f0\uad6c\ub97c \uc774\ub048 \ub9c8\uc6b0\ub77c \ubcfc\ub4dc\ub9ac\ub2c8 \uc815\uc2e0\uac74\uac15\uc758\ud559\uacfc \uad50\uc218\ub294 \u201c\uc77c\ubc18\uc801\uc73c\ub85c \ub1cc\ub97c \uc5f0\uad6c\ud560 \ub54c \uc2e4\ud5d8\uc6a9 \uc950\uc758 \uc791\uc740 \ub1cc\ub97c \uc774\uc6a9\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\ub2e4. \uacfc\ud559\uc790\ub4e4\uc740 \uc950\uc758 \ub1cc\ub97c \uc790\ub974\uace0 \uadf8 \uc548\uc758 \uc138\ud3ec\ub97c \ub4e4\uc5ec\ub2e4\ubcf4\uace0 \uc138\ud3ec\uc758 \uac1c\uc218\ub97c \uc138\ub294 \ubc29\uc2dd\uc73c\ub85c \uc778\uac04\uc758 \ub1cc\ub97c \ucd94\uc815\ud55c\ub2e4\u201d\uba74\uc11c \u201c\ud558\uc9c0\ub9cc \uc778\uac04\uc758 \ub1cc\ub294 \uadf8\ubcf4\ub2e4 \ud6e8\uc52c \ub354 \ud06c\uace0 \ubcf5\uc791\ud558\ub2e4. \uc6b0\ub9ac\ub294 \uc18c\ud504\ud2b8\uc6e8\uc5b4 \ud504\ub85c\uadf8\ub7a8\uacfc \ud604\ubbf8\uacbd \uad00\ucc30\uc744 \ud1b5\ud574 \uc778\uac04\uc758 \ub1cc\uc5d0\uc11c \uc0c8\ub86d\uac8c \ub9cc\ub4e4\uc5b4\uc9c0\ub294 \uc138\ud3ec\ub97c \ucc3e\uc544\ub0c8\ub2e4\u201d\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n

\uc774\uc5b4 \u201c\ub1cc\uc758 \ud574\ub9c8\uc5d0\uc11c \uc9c0\uc18d\uc801\uc73c\ub85c \uc0c8\ub85c\uc6b4 \uc138\ud3ec\uac00 \ub9cc\ub4e4\uc5b4\uc9c4\ub2e4\ub294 \uc0ac\uc2e4\uc740 \ub098\uc774\uac00 \ub4e4\uc5b4\ub3c4 \ub1cc \uac74\uac15\uc744 \uc720\uc9c0\ud560 \uc218 \uc788\ub294 \ubc29\ubc95\uc744 \ucc3e\ub294\ub370 \ub3c4\uc6c0\uc774 \ub420 \uac83\u201d\uc774\ub77c\uace0 \ub367\ubd99\uc600\ub2e4.<\/p>\n

\uc790\uc138\ud55c \uc5f0\uad6c\uacb0\uacfc\ub294 5\uc77c \ud559\uc220\uc9c0 \u2018\uc140 \uc904\uae30\uc138\ud3ec\u2019(Cell<\/span>\u00a0stem<\/span>\u00a0cell<\/span>)\uc5d0 \uac8c\uc7ac\ub410\ub2e4.<\/p>\n

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87\uc138 \ub178\uc778\uc5d0\uac8c\uc11c\ub3c4 \ub1cc\uc138\ud3ec \uc0dd\uc131<\/h5>\n

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43~87\uc138 \ub1cc\uc11c \uc218\ub9cc \uac1c \uc591\uc131 \ub1cc\uc138\ud3ec \ubc1c\uacac<\/b><\/p>\n

\ub1cc \uacfc\ud559\uacc4\uc5d0 \uc624\ub7ab\ub3d9\uc548 \ub04c\uc5b4\uc628 \ub9e4\uc6b0 \ub728\uac70\uc6b4 \ub17c\uc7c1\uac70\ub9ac\uac00 \uc788\ub2e4.<\/p>\n

\ucd9c\uc0dd \uc774\ud6c4 \uccad\uc18c\ub144\uae30\uae4c\uc9c0 \uc2e0\uacbd\uc870\uc9c1\uc774 \uacc4\uc18d \uc0dd\uc131\ub418\ub294 \uac83\uc740 \ud2c0\ub9bc\uc5c6\uc9c0\ub9cc \uccad\uc18c\ub144\uae30\uac00 \uc9c0\ub09c \ud6c4\uc5d0\ub3c4 \uc0c8\ub85c\uc6b4 \ub1cc\uc138\ud3ec\uac00 \uacc4\uc18d \uc0dd\uc131\ub418\uace0 \uc788\ub294\uc9c0 \uadf8 \uc5ec\ubd80\ub97c \ub193\uace0 \uc8fc\uc7a5\uc774 \uc5c7\uac08\ub9ac\uace0 \uc788\uc5c8\ub2e4.<\/p>\n

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\uadf8\ub7ec\ub098 \ucd5c\uadfc \uc5f0\uad6c \uacb0\uacfc\ub85c \uc0c1\ud669\uc774 \ubc14\ub00c\uace0 \uc788\ub2e4. 26\uc77c \u2018\uc0ac\uc774\uc5b8\uc2a4\u2019, \u2018\uac00\ub514\uc5b8\u2019 \ub4f1 \uc8fc\uc694 \uc5b8\ub860\ub4e4\uc740 \uacfc\ud559\uc790\ub4e4\uc774 \uc911\ub144\uc774 \uc9c0\ub09c \ud6c4 90\uc138\uac00 \uac00\uae4c\uc6cc\uc838\ub3c4 \uc0c8\ub85c\uc6b4 \ub1cc\uc138\ud3ec\uac00 \uc0dd\uc131\ub418\ub294 \ub4f1 \uc0ac\ub78c\uc758 \uc77c\uc0dd\uc5d0 \uac78\uccd0 \uc2e0\uacbd\uc870\uc9c1\uc774 \ub9cc\ub4e4\uc5b4\uc9c0\uace0 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud588\ub2e4\uace0 \uc804\ud588\ub2e4.<\/p>\n

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\uc911\ub144\uc774 \uc9c0\ub09c \ud6c4 90\uc138\uc5d0 \uac00\uae4c\uc6cc\uc838\ub3c4 \uc0c8\ub85c\uc6b4 \ub1cc\uc138\ud3ec\uac00 \uc0dd\uc131\ub418\ub294 \ub4f1 \uc0ac\ub78c\uc758 \uc77c\uc0dd\uc5d0 \uac78\uccd0 \uc2e0\uacbd\uc870\uc9c1\uc774 \ub9cc\ub4e4\uc5b4\uc9c0\uace0 \uc788\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \ubc1c\ud45c\ub410\ub2e4. \uc0ac\uc9c4\uc740 68\uc138 \uc131\uc778 \ub1cc\uc870\uc9c1. \ubd89\uc740 \uc0c9 \ubd80\ubd84\uc774 \uc0c8\ub85c \uc0dd\uc131\ub41c \uc80a\uc740 \ub1cc\uc138\ud3ec\ub4e4\uc774\ub2e4. \u24d2LlorensLab<\/span><\/span> <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\n\uc54c\uce20\ud558\uc774\uba38 \ud658\uc790\uc758 \ub274\ub7f0\uc740 30% \uc801\uc5b4\u00a0<\/strong><\/p>\n

\uc5f0\uad6c\uc9c4\uc740 \ub610 \uacfc\uac70\uc758 \uc2e0\uacbd\uc0dd\uc131(neurogenesis) \uacfc\uc815\uc744 \ubd84\uc11d\ud558\ub294 \uacfc\uc815\uc5d0\uc11c \ubc29\ubc95\ub860\uc801\uc778 \uc624\ub958 \ub54c\ubb38\uc5d0 \uc911\ub144 \uc774\ud6c4 \ub1cc\uc138\ud3ec \uc0dd\uc131 \uacfc\uc815\uc744 \ubc1d\ud600\ub0b4\ub294\ub370 \uc2e4\ud328\ud588\ub2e4\ub294 \ub0b4\uc6a9\uc758 \ub17c\ubb38\uc744 \ubc1c\ud45c\ud588\ub2e4.<\/p>\n

\uc5f0\uad6c\uc5d0 \ucc38\uc5ec\ud55c\u00a0\u2018\uc5b4\ub9b0\uc774\ub97c \uc704\ud55c \ubcd1\uc6d0\u2019\uc758 \ub1cc\uacfc\ud559\uc790 \ud3f4 \ud504\ub7ad\ud06c\ub79c\ub4dc(Paul Frankland) \uc120\uc784\uc5f0\uad6c\uc6d0\uc740 \u201c\uc774\ubc88 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc0ac\ub78c\uc758 \uc804 \uc0dd\uc560\uc5d0 \uac78\uccd0 \uc2e0\uacbd\uc0dd\uc131\uc774 \uc774\ub8e8\uc5b4\uc9c0\uace0 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\ub2e4.\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\uc774\ubc88 \uc5f0\uad6c \uacb0\uacfc\ub294 \ud559\uc220\uc9c0\u00a0\u2018\ub124\uc774\ucc98 \uba54\ub514\uc2e0\u2019 25\uc77c\uc790\uc5d0 \uac8c\uc7ac\ub410\ub2e4. \ub17c\ubb38 \uc81c\ubaa9\uc740 \u2018 Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer\u2019s disease\u2018\uc774\ub2e4.<\/p>\n

\uc5f0\uad6c\ud300\uc740 \uc774\ubc88 \uc5f0\uad6c\ub97c \ud1b5\ud574 43~87\uc138\uc758 \uc131\uc778 13\uba85\uc73c\ub85c\ubd80\ud130 \ub1cc\uc870\uc9c1\uc744 \uae30\uc99d\ubc1b\uc544 24\uc2dc\uac04\uc774\ub77c\ub294 \uc9e7\uc740 \uc2dc\uac04 \ub3d9\uc548 \uc774\ub4e4 \ub1cc\uc138\ud3ec\ub97c \ubd84\uc11d\ud55c \uacb0\uacfc \uc218\ub9cc \uac1c\uc758 \uac74\uac15\ud55c \uc591\uc131 \ub1cc\uc138\ud3ec\ub97c \ubc1c\uacac\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\uc774\ub4e4 \ub1cc\uc138\ud3ec\ub4e4\uc740 \ud559\uc2b5\uacfc \uae30\uc5b5\uc744 \uad00\uc7a5\ud558\ub294 \ud574\ub9c8\uccb4 \ub0b4\ubd80\uc5d0 \uc704\uce58\ud55c \uce58\uc0c1\ud68c(dentate gyrus) \uc18d\uc5d0\uc11c \ud65c\ub3d9\ud558\ub358 \uc138\ud3ec\ub4e4\uc774\ub2e4.<\/p>\n

\uc5f0\uad6c\uc5d0 \ucc38\uc5ec\ud55c \uc2a4\ud398\uc778 \uc138\ubca0\ub85c \uc624\ucd08\uc544 \ubd84\uc790\uc0dd\ubb3c\ud559 \uc13c\ud130\uc758 \ub1cc\uacfc\ud559\uc790 \ub9c8\ub9ac\uc544 \ub85c\ub80c\uc2a4-\ub9c8\ud2f4(Mar\u00eda Llorens-Mart\u00edn) \ubc15\uc0ac\ub294 \u201c\uc774\ub4e4 \ub274\ub7f0(\uc2e0\uacbd\uc138\ud3ec) \ub4e4\uc740 \uc544\uc9c1 \ubc1c\ub2ec\ud558\uc9c0 \uc54a\ub294 \uac00\uc9c0\ub4e4\uacfc \ud568\uaed8 \ubd80\ub4dc\ub7fd\uace0 \ud3ec\ub3d9\ud3ec\ub3d9\ud55c \ubaa8\uc2b5\uc73c\ub85c \uc80a\uace0 \uc0dd\uc0dd\ud55c \ubaa8\uc2b5\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\uc5c8\ub2e4.\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\ud2b9\ud788 43\uc138 \uae30\uc99d\uc790\uc758 \ub1cc\uc870\uc9c1 1 \uc785\ubc29\ubc00\ub9ac\ubbf8\ud130 \ub0b4\uc5d0\uc11c \uc57d 4\ub9cc 2000\uac1c\uc758 \ubbf8\uc131\uc219\ud55c \uc2e0\uc0dd \ub274\ub7f0\ub4e4\uc744 \ubc1c\uacac\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\uc774\ud6c4 \uc5f0\ub839\ub300\uc11c\ubd80\ud130\u00a087\uc138\uae4c\uc9c0 \uae30\uc99d\uc790 \ub1cc\uc870\uc9c1 \uc548\uc5d0 \uc788\ub294 \uc2e0\uc0dd \ub1cc\uc138\ud3ec\uc758 \uc218\ub97c \uc9d1\uacc4\ud55c \uacb0\uacfc 87\uc138 \ub178\uc778\uc758 \ub1cc\uc138\ud3ec \uc218\uac00 43\uc138 \uae30\uc99d\uc790\uc640 \ube44\uad50\ud574 \uc57d 30% \uac10\uc18c\ud55c \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \uc774\ub294 87\uc138 \ub178\uc778\uc758 \ub1cc\uc870\uc9c1 \uc548\uc5d0 70%\uc758 \uc80a\uc740 \ub1cc\uc138\ud3ec\uac00 \uc0dd\uc131\ub3fc \uc788\uc74c\uc744 \ub9d0\ud574\uc8fc\ub294 \uac83\uc774\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc54c\uce20\ud558\uc774\uba38, \uce58\ub9e4 \ub4f1 \ub1cc\uc9c8\ud658\uc5d0 \uac78\ub9b0 \ud658\uc790\uc758 \uacbd\uc6b0 \ub1cc\uc138\ud3ec \uc218\uac00 \ud06c\uac8c \uac10\uc18c\ud558\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4.<\/p>\n

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\uc77c\ubc18\uc778\uc758 \ub1cc (\uc67c\ucabd)\uc640 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\uc758 \ub1cc (\uc624\ub978\ucabd)\uc758 \ube44\uad50 \u24d2\uc704\ud0a4\ud53c\ub514\uc544<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\uc5f0\uad6c\ud300\uc740 \ud2b9\ud788 \uc54c\uce20\ud558\uc774\uba38 \ud658\uc790\uc758 \uacbd\uc6b0 \ub1cc\uc138\ud3ec\uac00 \uc0dd\uc131\ub410\uc9c0\ub9cc \uc2e0\uc0dd \ub274\ub7f0\uc758 \uc218\uac00 \uac19\uc740 \uc5f0\ub839\uc758 \uac74\uac15\ud55c \ub178\uc778\uacfc \ube44\uad50\ud574 \uc57d 30% \uc801\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc73c\uba70, \uce58\ub9e4 \ud658\uc790\uc758 \uacbd\uc6b0\ub294 \uadf8 \uc218\uac00 \ub354 \uc904\uc5b4\ub4e4\uc5c8\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\n

\u201c\uae30\uc874 \uc8fc\uc7a5 \ub4a4\uc9d1\ub294 \uadc0\uc911\ud55c \ub370\uc774\ud130\u201d\u00a0<\/strong><\/p>\n

\uc624\ub79c \uae30\uac04 \ub3d9\uc548 \uacfc\ud559\uc790\ub4e4\uc740 \ub1cc\uc758 \uc2e0\uacbd\uc138\ud3ec(neuron)\uac00 \uc0dd\uc131\ub418\uace0 \ubc1c\ub2ec\ud574 \uc18c\uba78\ud558\ub294 \uc2e0\uacbd\uc0dd\uc131\uc758 \uc21c\ud658 \uacfc\uc815\uc774 \uba48\ucd94\uba74\uc11c \uc6b0\uc6b8\uc99d, \uc54c\uce20\ud558\uc774\uba38\uc640 \uac19\uc740 \ub1cc\uc9c8\ud658\uc744 \ubd88\ub7ec\uc77c\uc73c\ud0a8\ub2e4\uace0 \ud310\ub2e8\ud558\uace0 \uc788\uc5c8\ub2e4.<\/p>\n

 <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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\ub274\ub7f0\uacfc \ub1cc \uc2e0\uacbd\uacfc\ud559 \uc77c\ub7ec\uc2a4\ud2b8 \u24d2 Pixabay<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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 <\/p>\n

\uadf8\ub7ec\ub098 \uc9c0\ub09c\ud574\u00a0\u2018\ub124\uc774\ucc98\u2019 \uc9c0\uc5d0 \uc774 \uc2e0\uacbd\uc0dd\uc131 \ud65c\ub3d9\uc774 \uccad\uc18c\ub144\uae30 \ub4e4\uc5b4\uc11c\uba74\uc11c \uc810\ucc28 \uc904\uc5b4\ub4e4\uace0 \uc788\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \ubc1c\ud45c\ub410\ub2e4. \uc774 \ub17c\ubb38 \ub0b4\uc6a9\uc740 \ub2e4\uc591\ud55c \ubc29\uc2dd\uc744 \ud1b5\ud574 \ub178\uc778 \ub1cc\uc5d0\uc11c \uc0c8\ub85c \ub9cc\ub4e4\uc5b4\uc9c4 \uc2e0\uacbd\uc138\ud3ec\ub97c \ubc1c\uacac\ud55c \uc774\uc804\uc758 \uc5f0\uad6c \uacb0\uacfc\ub97c \ubd80\uc815\ud558\ub294 \uac83\uc774\uc5c8\ub2e4.<\/p>\n

\ub2f9\uc2dc \ud504\ub7ad\ud06c\ub79c\ub4dc\uc640 \uac19\uc740 \ub1cc \uacfc\ud559\uc790\ub4e4\uc740 \ud559\uc2b5\uacfc \uae30\uc5b5\uc744 \uad00\uc7a5\ud558\ub294 \uc124\uce58\ub958\uc758 \ud574\ub9c8(hippocampus) \uc18d\uc5d0\uc11c \uc2e0\uacbd\uc0dd\uc131\uc774 \uc5b4\ub5bb\uac8c \uc774\ub8e8\uc5b4\uc9c0\uace0 \uc788\ub294\uc9c0 \uad00\ucc30\ud558\uace0 \uc788\uc5c8\ub2e4.<\/p>\n

\uc815\ubc18\ub300\uc758 \uc5f0\uad6c \uacb0\uacfc\uc5d0 \ub2f9\ud669\ud55c \uc5f0\uad6c\uc9c4\uc740 \uc2e0\uacbd\uc0dd\uc131\uacfc \uad00\ub828 \uadf8\ub3d9\uc548 \ub1cc \uacfc\ud559\uc790\ub4e4\uc774 \uc218\ud589\ud574\uc628 \uc5f0\uad6c \ubc29\uc2dd\uc5d0 \ubb38\uc81c\uac00 \uc788\uc744 \uc218 \uc788\ub2e4\uace0 \ubcf4\uc558\ub2e4.<\/p>\n

\uadf8\ub9ac\uace0 \uc9c0\ub09c\ud574 \uccad\uc18c\ub144\uae30\uae4c\uc9c0 \uc2e0\uacbd\uc0dd\uc131\uc774 \uc9c4\ud589\ub418\uace0 \uc788\ub2e4\ub294 \ub0b4\uc6a9\uc758 \ub17c\ubb38\uc744 \ubd84\uc11d\ud55c \uacb0\uacfc \ubb38\uc81c\uc810\uc744 \ubc1c\uacac\ud588\ub2e4.<\/p>\n

\uc5f0\uad6c\uc9c4\uc740\u00a02018\ub144 \ub17c\ubb38\uc744 \uc791\uc131\ud55c \uc5f0\uad6c\ud300\uc774 59\uac1c\uc758 \uc778\uac04 \ub1cc\uc870\uc9c1 \uc18d\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc138\ud3ec\ub97c \ucc3e\uace0 \uc788\uc5c8\ub2e4\ub294 \uac83\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n

\uadf8\ub7f0\ub370 \uc774\ub4e4 \ub1cc\uc870\uc9c1\ub4e4\uc740 \ub450\ub1cc\uc740\ud589(brain banks)\uc5d0\uc11c \uac00\uc838\uc628 \uac83\uc73c\ub85c \uc9e7\uac8c\ub294 \uc218\uac1c\uc6d4, \uae38\uac8c\ub294 \uc218\ub144\uac04 \uace0\uc815\uc561 \ud615\ud0dc\uc758 \ud30c\ub77c\ud3ec\ub984\uc54c\ub370\ud558\uc774\ub4dc(fixative paraformaldehyde) \uc18d\uc5d0 \uc7a0\uaca8 \uc788\ub358 \uac83\ub4e4\uc774\uc5c8\ub2e4.<\/p>\n

\uc5f0\uad6c\uc5d0 \ucc38\uc5ec\ud55c \ub1cc\uacfc\ud559\uc790 \ub9c8\ub9ac\uc544 \ub85c\ub80c\uc2a4-\ub9c8\ud2f4(Mar\u00eda Llorens-Mart\u00edn) \ubc15\uc0ac\ub294 \u201c\uc774 \ud30c\ub77c\ud3ec\ub984\uc54c\ub370\ud558\uc774\ub4dc\ub294 \ub2e8\uae30\uac04 \ub3d9\uc548\uc5d0\ub294 \ubd80\ud328\ub97c \ubc29\uc9c0\ud558\uc9c0\ub9cc 48\uc2dc\uac04\uc774 \uc9c0\ub098\uba74 \uc138\ud3ec\ub97c \uad6c\uc131\ud558\uace0 \uc788\ub294 \uc870\uc9c1\uc744 \ubb36\uc5b4 \uc824(gel) \ud615\ud0dc\ub85c \ubcc0\ud615\uc2dc\ud0a8\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\uc774\ub7f0 \ud604\uc0c1\uc740 \uc138\ud3ec\uc0dd\uc131\uc744 \uad00\ucc30\ud558\uae30 \uc704\ud574 \uc8fc\uc785\ud55c \ud615\uad11\ud56d\uccb4(fluorescent antibodies)\uac00 \uc138\ud3ec\uc0dd\uc131\uc5d0 \uc788\uc5b4 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uc2e0\uacbd\uc138\ud3ec\uc774\ub3d9 \ub2e8\ubc31\uc9c8 DCX(Doublecortin)\uc640 \uacb0\ud569\ud558\ub294 \uac83\uc744 \uc5b4\ub835\uac8c \ub9cc\ub4e0\ub2e4\ub294 \uac83.<\/p>\n

\ub9c8\ub9ac\uc544 \ubc15\uc0ac\ub294\u00a0\u201c\uacb0\uacfc\uc801\uc73c\ub85c \uc5f0\uad6c\uc5d0 \ud22c\uc785\ub41c \ub1cc\uc138\ud3ec\ub4e4\uc774 \ud30c\ub77c\ud3ec\ub984\uc54c\ub370\ud558\uc774\ub4dc\uc5d0 6\uac1c\uc6d4\uc774 \ub118\uac8c \ub2f4\uaca8 \uc788\uc5c8\ub2e4\uba74 \uc5f0\uad6c\uac00 \ubd88\uac00\ub2a5\ud560 \uc815\ub3c4\u201d\ub77c\uba70, \u201c\uc824 \ud604\uc0c1\uc73c\ub85c \uc778\ud574 \ub1cc\uc138\ud3ec \uc0dd\uc131 \uacfc\uc815\uc744 \uc815\ud655\ud788 \uce21\uc815\ud560 \uc218 \uc5c6\uc5c8\uc744 \uac83\u201d\uc774\ub77c\uace0 \ubcf4\uace0 \uc788\ub2e4.<\/p>\n

\uc5f0\uad6c\uc5d0 \ucc38\uc5ec\ud55c \ubbf8\uad6d \ud53c\uce20\ubc84\uadf8\ub300 \ub1cc\uacfc\ud559\uc790 \uc200 \uc18c\ub810\uc2a4(Shawn Sorrells) \uad50\uc218\ub294 \u201c2019\ub144\uc5d0 \ubc1c\uacac\ud55c \uc80a\uc740(new) \ub1cc\uc138\ud3ec\ub4e4\uc774 \uc5b4\ub9b0\uc544\uc774\uc5d0\uac8c\uc11c \ubc1c\uacac\ub418\ub294 \ub1cc\uc138\ud3ec\uc640 \uc720\uc0ac\ud55c \uac83\u201d\uc774\ub77c\uba70, \u201c\uc131\uc778\uc774 \ub418\uba74 \uc2e0\uacbd\uc138\ud3ec\uac00 \uc0dd\uc131\ub418\uc9c0 \uc54a\ub294\ub2e4\ub294 \uc8fc\uc7a5\uc744 \ub4a4\uc9d1\ub294 \uadc0\uc911\ud55c \ub370\uc774\ud130\u201d\ub77c\uace0 \ub9d0\ud588\ub2e4.
\n\uc774
\n\ubc88 \uc5f0\uad6c \uacb0\uacfc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \ub1cc \uacfc\ud559\uc790\ub4e4 \uc0ac\uc774\uc758 \uc2e0\uacbd\uc138\ud3ec \uc0dd\uc131\uacfc \uad00\ub828\ub41c \ub17c\ub780\uc774 \uac00\ub77c\uc549\uc744 \uc9c0\ub294 \uc544\uc9c1 \ubbf8\uc9c0\uc218\ub2e4.<\/p>\n

\ubbf8\uad6d \uba54\ub9b4\ub79c\ub4dc \uc8fc\uc758 \uad6d\ub9bd\ubcf4\uac74\uc5f0\uad6c\uc6d0(NIMH)\uc758 \ub1cc\uacfc\ud559\uc790 \ud788\ub354 \uce74\uba54\ub860(Heather Cameron) \ubc15\uc0ac\ub294 \ub17c\ub780\uc774 \uc885\uc2dd\ub420 \uc218 \uc788\uaca0\ub290\ub0d0\ub294 \u2018\uc0ac\uc774\uc5b8\uc2a4\u2019 \uae30\uc790 \uc9c8\ubb38\uc5d0 \u201c\ubc18\ub300 \uc9c4\uc601\uc5d0\uc11c \ubc1b\uc544\ub4e4\uc77c\uc9c0\ub294 \uc544\uc9c1 \ubaa8\ub978\ub2e4\u201d\uba70, \u201c\uadf8\ub7ec\ub098 \uc774 \ub17c\ub780\uc774 \uc885\uc2dd\ub3fc\uc57c \ud55c\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

 <\/p>\n

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(\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

  \uc0ac\uc9c4=123rf.com   \ub098\uc774\uac00 \ub4e4\uba74 \ub1cc\uc138\ud3ec\uac00 \u2018\uc8fd\uae30\ub9cc\u2019 \ud55c\ub2e4\ub294 \uae30\uc874\uc758 \ud559\uc124\uc744 \ub4a4\uc9d1\ub294 \uc5f0\uad6c\uacb0\uacfc\uac00 \ub098\uc654\ub2e4. \ubbf8\uad6d \ub274\uc695 \uceec\ub7fc\ube44\uc544\ub300 \uc5f0\uad6c\uc9c4\uc5d0 \ub530\ub974\uba74 \uc6b0\ub9ac \ub1cc\ub294 \ub098\uc774\uac00 \ub4e0 \uc774\ud6c4\uc5d0\ub3c4 \uc9c0\uc18d\uc801\uc73c\ub85c \uc0c8\ub85c\uc6b4(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[33,29],"tags":[],"class_list":["post-3047","post","type-post","status-publish","format-standard","hentry","category-do-biology","category-lets-do-science"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":2609,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2609","url_meta":{"origin":3047,"position":0},"title":"\uc778\uac04\uc740 \uc65c \uc815\uc2e0\uc9c8\ud658\uc5d0 \uc2dc\ub2ec\ub824\uc57c \ud560\uae4c","author":"biochemistry","date":"January 31, 2019","format":false,"excerpt":"\u00a0 \u00a0 [\uc694\uc57d]\u00a0\uc138\ud0c1\uae30\ub294 \ud55c\ubc88 \uace0\uc7a5 \ub098\uba74 \uace0\uce58\uae30 \uc5b4\ub835\uace0 \ub3c8\ub3c4 \ub9ce\uc774 \ub4e0\ub2e4.\u00a0\ub300\uc2e0 \uc6b0\ub9b0 \ucd5c\uc2e0\uc2dd \uc138\ud0c1\uae30\uc758 \ub6f0\uc5b4\ub09c \uc131\ub2a5\uacfc \ud3b8\ub9ac\ud568\uc744 \ub204\ub9b0\ub2e4.\u00a0\ud765\ubbf8\ub86d\uac8c\ub3c4 \ub3d9\ubb3c\uacfc \ub2e4\ub978 \uc778\uac04 \ub1cc\uc758 \ub6f0\uc5b4\ub09c \uc778\uc9c0\ub2a5\ub825 \uc5ed\uc2dc \uc9c4\ud654 \uacfc\uc815\uc5d0\uc11c \ubcd1\uc5d0 \ub300\ud55c \uc800\ud56d\uc131\uc744 \ud3ec\uae30\ud558\uace0 \uc5bb\uc740 \ubc18\ub300\uae09\ubd80\ub77c\ub294 \uc774\ub860\uc774 \ub098\uc654\ub2e4. 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\u00a0 (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) \u00a0 \uc774\ubbf8\uc9c0 \ud06c\uac8c \ubcf4\uae30 \u00a0 \u00a0 \uc554\uacfc \uce58\ub9e4, \uadf8\ub9ac\uace0 \uc2ec\uc7a5\uc9c8\ud658 \uac19\uc740 \ub178\uc778\ubcd1\uc744 \uce58\ub8cc\ud558\uae30 \uc704\ud574 \uc804 \uc138\uacc4 \uc218\uc2ed \uac1c\uc758 \uc2e0\uc0dd\uae30\uc5c5\uc774 \uc5f0\uad6c\uc6a9\uc73c\ub85c \uc80a\uc740 \uc131\uc778\ub4e4\uc5d0\uac8c\uc11c \ud53c\ub97c \uc5bb\uae30 \uc704\ud574 \uc560\ub97c \uc4f0\uace0 \uc788\ub294 \uac83\uc73c\ub85c \uc804\ud574\uc84c\ub2e4. \uc774\uc5d0 \ub300\ud574 \uc601\uad6d \uc720\ub2c8\ubc84\uc2dc\ud2f0\uce7c\ub9ac\uc9c0\ub7f0\ub358(UCL)\uc758 \uc720\uc804\ud559\uc790 \ub370\uc784 \ub9b0\ub2e4 \ud30c\ud2b8\ub9ac\uc9c0\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3085,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3085","url_meta":{"origin":3047,"position":4},"title":"\u2018\uc0dd\uccb4\uacf5\ud559 \ub208\u2019\uc73c\ub85c \ub2e4\uc2dc \ub208 \ub72c \uc2dc\uac01\uc7a5\uc560\uc778 & \uc8fd\uc740 \uc9c0 5\uc2dc\uac04 \uc9c0\ub09c \ub208\uc744 \ub418\uc0b4\ub838\ub2e4\u2026\uc2e4\uba85 \uce58\ub8cc \ud68d\uae30\uc801 \ubc1c\uc804 \uae30\ub300","author":"biochemistry","date":"March 31, 2019","format":false,"excerpt":"\u00a0 \u00a0 \uc2dc\ub825\uc744 \uc644\uc804\ud788 \uc783\uc5c8\ub358 40\ub300 \uc5ec\uc131\uc774 \uc0dd\uccb4\uacf5\ud559 \ub208\uc744 \uc774\uc2dd\ubc1b\uace0 \ub2e4\uc2dc \uc138\uc0c1\uc744 \ubcfc \uc218 \uc788\uac8c \ub410\ub2e4. \uc62c\ud574 49\uc138\uc778 \uc601\uad6d \uc5ec\uc131 \ub77c\uc774\uc5b8 \ub8e8\uc774\uc2a4\ub294 \uc720\uc804\uc801 \ub9dd\ub9c9\uc9c8\ud658\uc778 \ub9dd\ub9c9\uc0c9\uc18c\ubcc0\uc131\uc73c\ub85c 5\uc0b4 \ub54c\ubd80\ud130 \uc11c\uc11c\ud788 \uc2dc\ub825\uc744 \uc783\uae30 \uc2dc\uc791\ud574 16\ub144 \uc804 \ubd80\ud130\ub294 \uc624\ub978\ucabd \ub208\uc73c\ub85c\ub294 \uc544\ubb34\uac83\ub3c4 \ubcfc \uc218 \uc5c6\ub294 \uc0c1\ud0dc\uac00 \ub410\ub2e4. \uc67c\ucabd \ub208\uc758 \uc2dc\ub825\uc740 \ubbf8\uc57d\ud558\uac8c \ub0a8\uc544 \ub0a8\uc544\uc788\ub294 \uc0c1\ud0dc\uc600\uc9c0\ub9cc \uc6c0\uc9c1\uc774\ub294\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3070,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3070","url_meta":{"origin":3047,"position":5},"title":"\uc2e4\ud5d8\uc2e4\uc11c \ub1cc\uac00 \uc790\ub77c\uace0 \uc788\ub2e4? 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