{"id":3028,"date":"2019-03-29T23:15:25","date_gmt":"2019-03-29T14:15:25","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=3028"},"modified":"2019-11-05T12:12:05","modified_gmt":"2019-11-05T03:12:05","slug":"%eb%a9%b4%ec%97%ad%ea%b8%b0%eb%8a%a5%ea%b3%bc-%eb%85%b8%ed%99%94%ec%97%90-%ec%98%81%ed%96%a5-%eb%af%b8%ec%b9%98%eb%8a%94-%ec%9e%a5%eb%82%b4-%eb%af%b8%ec%83%9d%eb%ac%bc","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3028","title":{"rendered":"\uba74\uc5ed\uae30\ub2a5\uacfc \ub178\ud654\uc5d0 \uc601\ud5a5 \ubbf8\uce58\ub294 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c & \uc7a5\ub0b4\uc138\uade0\uc774 \u2018\uac74\uac15 \ub098\uc774\u2019 \uacb0\uc815"},"content":{"rendered":"

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[<\/b>\uc694\uc57d<\/b>]\u00a0<\/b>\uc2a4\uc704\uc2a4 \ub85c\uc794\uc5f0\ubc29\uacf5\uacfc\ub300\ud559<\/b>(<\/b>EPFL)\u00a0<\/b>\uacfc\ud559\uc790\ub4e4\uc740 \uba74\uc5ed\uacc4\uc758 \uae30\ub2a5\uc7a5\uc560\uac00 \uc5b4\ub5bb\uac8c \uc7a5\ub0b4 \uc138\uade0\uc758 \uacfc\ubd80\ud558\ub97c \uc720\ubc1c\uc2dc\ud0a4\ub294\uc9c0 \ubc1c\uacac\ud588\ub2e4<\/b>.\u00a0<\/b>\uc138\uade0\uc740 \uacfc\ub3c4\ud55c \uc816\uc0b0\uc744 \ub9cc\ub4e4\uc5b4\ub0b4\uace0 \uc138\ud3ec \uc190\uc0c1\uacfc \ub178\ud654\uad00\ub828 \uc9c8\ud658\uc744 \uc720\ubc1c\uc2dc\ud0a4\ub294 \ud65c\uc131\uc0b0\uc18c \uc0dd\uc131\uc744 \uc720\ubc1c\uc2dc\ud0a4\uac8c \ub41c\ub2e4<\/b>. (<\/b>2018.11)<\/b><\/p>\n

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\uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c \uc5f0\uad6c\uc5d0 \ub9ce\uc774 \ud65c\uc6a9\ub418\ub294 \ucd08\ud30c\ub9ac \ucd9c\ucc98 : iStock<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\uc7a5\ub0b4 \uc138\uade0\uc774 \uc624\ub298\ub0a0 \uc0dd\ubb3c\ud559\uacfc \uc758\ud559 \uc5f0\uad6c\uc5d0\uc11c \uac00\uc7a5 \uc911\uc694\ud55c \ud14c\ub9c8\uac00 \ub41c \uac83\uc740 \ubd84\uba85\ud558\ub2e4. \ucd5c\uadfc \uc77c\ub828\uc758 \uc5f0\uad6c\uacb0\uacfc\uc5d0 \ub530\ub974\uba74 \uc7a5\uc5d0 \uc11c\uc2dd\ud558\ub294 \uc5ec\ub7ec \uc885\ub958\uc758 \uc138\uade0\ub4e4\uc774 \uba74\uc5ed \uc2dc\uc2a4\ud15c\uc744 \ube44\ub86f\ud55c \ub2e4\uc591\ud55c \uc2e0\uccb4 \uae30\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4\ub294 \uac83\uc744 \uc54c\uac8c \ub410\ub2e4.<\/p>\n

\uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uc758 \uc11c\ub85c \ub2e4\ub978 \uac1c\uccb4\uad70\ub4e4\uc740 \uac70\uc758 \ubaa8\ub4e0 \ub3d9\ubb3c\uc5d0 \uc874\uc7ac\ud558\uba74\uc11c \u2018\uacf5\uc0dd\u2019\uc774\ub77c\uace0 \ubd88\ub9ac\ub294 \ud2b9\uc815 \uae30\ub2a5\uc801 \uade0\ud615\uc744 \uc774\ub8e8\uba74\uc11c \uc0b4\uace0 \uc788\ub2e4. \uc9c8\ubcd1\uc774\ub098 \ud56d\uc0dd\uc81c \uac19\uc740 \uc57d\ubb3c\uc744 \uacfc\ub2e4\ubcf5\uc6a9\ud560 \uacbd\uc6b0 \uc624\ud788\ub824 \uc9c8\ubcd1 \uac10\uc5fc \uc704\ud5d8\uc774 \ucee4\uc9c0\uace0 \uc218\uba85\uc774 \uc904\uc5b4\ub4dc\ub294 \ub4f1 \u2018\uacf5\uc0dd \uc7a5\uc560\u2019 \uc0c1\ud0dc\uac00 \ubc1c\uc0dd\ud55c\ub2e4. \uc774\ub7f0 \uc9c0\uc2dd\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uc7a5\ub0b4 \uc138\uade0\uc774 \uac74\uac15\uc5d0 \uc5b4\ub5bb\uac8c \ub3c4\uc6c0\uc744 \uc8fc\ub294\uc9c0 \ub610\ub294 \uadf8 \ubc18\ub300\uc758 \uacbd\uc6b0\ub294 \uc5b4\ub5a4\uc9c0\uc5d0 \ub300\ud574\uc11c \uba85\ud655\ud788 \uc54c\ub824\uc9c0\uc9c0 \uc54a\uc558\ub2e4.<\/p>\n

\uc2a4\uc704\uc2a4 \ub85c\uc794\uc5f0\ubc29\uacf5\uacfc\ub300(EPFL) \uae00\ub85c\ubc8c\ubcf4\uac74\uc5f0\uad6c\uc18c \ube0c\ub8e8\ub178 \ub974\ub9c8\uc774\ub728 \uad50\uc218\ud300\uc758 \uc774\uace0\ub974 \uc774\uc544\uccb8\ucf54 \ubc15\uc0ac\ub294 \uba74\uc5ed\uacc4\uc758 \ubb38\uc81c\uac00 \uacf5\uc0dd \uc7a5\uc560\ub97c \uc720\ubc1c\uc2dc\ud0a4\uace0 \ub178\ud654 \uad00\ub828 \uc99d\uc0c1\uc744 \ucd09\uc9c4\uc2dc\ud0a4\ub294 \uba54\ucee4\ub2c8\uc998\uc744 \ubc1c\uacac\ud588\ub2e4.<\/p>\n

\uc5f0\uad6c\ud300\uc740 \uc7a5\ub0b4 \uc138\uade0 \uc0dd\ubb3c\ud559\uc744 \uc5f0\uad6c\ud558\ub294\ub370 \uc790\uc8fc \uc4f0\uc774\ub294 \ucd08\ud30c\ub9ac\ub97c \uc774\uc6a9\ud588\ub2e4. \uc5f0\uad6c\ud300\uc740 \uc7a5\ub0b4 \uc138\uade0\uacfc \uba74\uc5ed\uacc4 \uc0ac\uc774\uc758 \uc0c1\ud638\uc791\uc6a9\uc744 \ud0d0\uad6c\ud558\uae30 \uc704\ud574 PGRP-SD\ub77c\uace0 \ubd88\ub9ac\ub294 \uc218\uc6a9\uccb4 \ub2e8\ubc31\uc9c8\uc5d0 \uc8fc\ubaa9\ud588\ub2e4.\u00a0 \uc774 \ub2e8\ubc31\uc9c8\uc740 \ud328\ud134\uc778\uc2dd \uc218\uc6a9\uccb4\uc758 \ud55c \uc885\ub958\ub85c \uc774\uace0\ub974 \uc774\uc544\uccb8\ucf54 \ubc15\uc0ac\ub294 2016\ub144\uc5d0 PGRP-SD\uac00 \uc678\ubd80\uc758 \uc138\uade0\uc131 \ubcd1\uc6d0\uade0\uc744 \ud3ec\ucc29\ud558\uace0 \uc774\uac83\uc5d0 \ub300\ud56d\ud574 \ud30c\ub9ac\uc758 \uba74\uc5ed\uacc4\ub97c \uc791\ub3d9\uc2dc\ud0a8\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud55c \ubc14 \uc788\ub2e4.<\/p>\n

\uc774\ubc88 \uc5f0\uad6c\uc5d0\uc11c \uacfc\ud559\uc790\ub4e4\uc740 \uc6b0\uc120 PGRP-SD \uc720\uc804\uc790\ub97c \ucc28\ub2e8\ud574 \uba74\uc5ed \uc2dc\uc2a4\ud15c\uc774 \ud30c\uad34\ub41c \ud30c\ub9ac\ub97c \ub9cc\ub4e4\uc5c8\ub2e4. \uc774 \ub3cc\uc5f0\ubcc0\uc774 \ud30c\ub9ac\ub294 \uc77c\ubc18 \ud30c\ub9ac\ubcf4\ub2e4 \uc218\uba85\uc774 \uc9e7\uc558\uace0 \uc7a5\ub0b4 \uc138\uade0 \uc911 \uc816\uc0b0\uc744 \ub9cc\ub4e4\uc5b4 \ub0b4\ub294 \ubc15\ud14c\ub9ac\uc544\uac00 \ube44\uc815\uc0c1\uc801\uc73c\ub85c \ub9ce\uc544\uc838 \uc788\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\ub2e4.<\/p>\n

\uc774 \uac19\uc740 \uc0dd\ubb3c\ud559\uc801 \uc601\ud5a5\uc744 \uc870\uc0ac\ud55c \uacb0\uacfc \uacfc\ud559\uc790\ub4e4\uc740 \ubc15\ud14c\ub9ac\uc544\ub3c4 \uacfc\ub3c4\ud55c \uc816\uc0b0\uc744 \ub9cc\ub4e4\uc5b4 \ub0bc \uc218 \uc788\ub2e4\ub294 \uac83\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\ub2e4. \uc774\uac83\uc740 \ucc28\ub840\ub85c \uc138\ud3ec\uc5d0 \uc190\uc0c1\uc744 \uc785\ud788\uace0 \uc138\ud3ec \uc870\uc9c1 \ub178\ud654\ub97c \ucd09\uc9c4\uc2dc\ud0a4\ub294 \ud65c\uc131\uc0b0\uc18c \uc885 \uc0dd\uc131\uc744 \ucd09\ubc1c\uc2dc\ucf30\ub2e4. \ubc18\ub300\ub85c \uacfc\ud559\uc790\ub4e4\uc774 PGRP-SD \uc720\uc804\uc790\ub97c \ud65c\uc131\ud654\uc2dc\ucf30\uc744 \ub54c\ub294 \uacf5\uc0dd\uc7a5\uc560\uac00 \ub098\ud0c0\ub098\uc9c0 \uc54a\uc558\uc73c\uba70 \uc2ec\uc9c0\uc5b4 \ud30c\ub9ac\uc758 \uc218\uba85\uc774 \ub298\uc5b4\ub098\uae30\uae4c\uc9c0 \ud588\ub2e4.<\/p>\n

\ube0c\ub8e8\ub178 \ub974\ub9c8\uc774\ub728 \uad50\uc218\ub294 \u201c\uacf5\uc0dd\uade0\uacfc \uc219\uc8fc \uc0ac\uc774 \ub300\uc0ac\uc791\uc6a9\uc744 \uad00\ucc30\ud55c \uacb0\uacfc \uc816\uc0b0\uade0\uc774 \uacfc\ub3c4\ud558\uac8c \ub9cc\ub4e4\uc5b4\uc9c8 \uacbd\uc6b0 \uc0c1\ud53c \uc190\uc0c1\uc744 \ucd09\uc9c4\uc2dc\ud0a4\ub294 \ud65c\uc131\uc0b0\uc18c\uac00 \uacfc\ub7c9\uc73c\ub85c \uc0dd\uc0b0\ub41c\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\ub2e4\u201d\uba70 \u201c\uc0ac\ub78c\uc744 \ube44\ub86f\ud55c \ud3ec\uc720\ub958\uc758 \uc7a5\uc5d0\uc11c\ub3c4 \uc720\uc0ac\ud55c \uba54\ucee4\ub2c8\uc998\uc73c\ub85c \uc791\ub3d9\ud558\uace0 \uc788\uc744 \uac83\uc73c\ub85c \uc0dd\uac01\ub41c\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\uc774\uace0\ub974 \uc544\uc774\uccb8\ucf54 \ubc15\uc0ac\ub294 \u201c\uc774\ubc88 \uc5f0\uad6c\ub294 \uc219\uc8fc\uc0dd\ubb3c\uc5d0\uc11c \ub178\ud654\uc5d0 \uc601\ud5a5\uc744 \uc904 \uc218 \uc788\ub294 \ud2b9\uc815 \uc7a5\ub0b4\ubbf8\uc0dd\ubb3c \uc131\ubd84\uacfc \ub300\uc0ac\uc0b0\ubb3c\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\ub2e4\u201d\ub77c\uba70 \u201c\ub098\uc774\uc640 \uad00\ub828\ub41c \uc9c8\ubcd1\uc744 \ub9c9\uc744 \uc218 \uc788\ub294 \ubcd1\ub9ac\ud559\uc801 \uc804\ub7b5 \uac1c\ubc1c\uc5d0 \ub3c4\uc6c0\uc774 \ub420 \uac83\u201d\uc774\ub77c\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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\uc7a5\ub0b4\uc138\uade0\uc774 \u2018\uac74\uac15 \ub098\uc774\u2019 \uacb0\uc815<\/h5>\n

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\uc6b0\ub9ac \ubab8 \uc18c\ud654\u00a0\uae30\uad00\uc5d0\ub294 \uc218\uc2ed\uc5b5 \ub9c8\ub9ac\uc758 \uc7a5 \ubc15\ud14c\ub9ac\uc544(gut bacteria)\uac00 \uc0b4\uace0 \uc788\ub2e4.<\/p>\n

\uc774 \ubc15\ud14c\ub9ac\uc544\ub4e4\uc740 \uc74c\uc2dd\uc744 \uc18c\ud654\uc2dc\ud0a4\ub294 \uc77c\ubd80\ud130 \uba74\uc5ed \uae30\ub2a5\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 \uc6b0\ub9ac \ubab8\uc758 \uac74\uac15\uc744 \uc720\uc9c0\ud558\ub294\ub370 \uc788\uc5b4\uc11c\u00a0\ub9e4\uc6b0 \uc911\uc694\ud55c \uc77c\ub4e4\uc744 \ud558\uace0 \uc788\ub2e4.<\/p>\n

\uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uacfc\ud559\uc790\ub4e4\uc740 \ub9c8\uc774\ud06c\ub85c\ubc14\uc774\uc634(microbiome)\uc774\ub77c \ubd88\ub9ac\ub294 \uc774 \ubbf8\uc0dd\ubb3c\uad70\uc720\uc804\uccb4\uc5d0 \ub300\ud574 \ub9ce\uc740 \uc0ac\uc2e4\uc744 \uc54c\uc9c0 \ubabb\ud558\uace0 \uc788\uc5c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ucd5c\uadfc \uc778\uacf5\uc9c0\ub2a5(AI)\uc744 \ub3d9\uc6d0\ud55c \ucca8\ub2e8 \uc5f0\uad6c\ubc29\uc2dd\uc744 \ud1b5\ud574 \uc774\uc804\uc5d0 \ubab0\ub790\ub358 \uc0c8\ub85c\uc6b4 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc9c0\uace0 \uc788\ub2e4.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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\uac74\uac15\ud55c \uc0ac\ub78c\uc77c\uc218\ub85d \ucc29\ud55c \uc7a5\ub0b4\uc138\uade0 \ubcf4\uc720\u00a0<\/strong><\/p>\n

12\uc77c \u2018\uc0ac\uc774\uc5b8\uc2a4\u2019 \uc9c0\uc5d0 \ub530\ub974\uba74 \ubbf8\uad6d\uc758 \uc2a4\ud0c0\ud2b8\uc5c5 \u2018\uc778\uc2e4\ub9ac\ucf54 \uba54\ub514\uc2a8(Insilico Medicine)\u2019\uc758 \uacfc\ud559\uc790\ub4e4\uc740 \uc804 \uc138\uacc4\uc5d0 \uac70\uc8fc\ud558\uace0 \uc788\ub294 \uc218\ucc9c \uba85\uc758 \uc7a5 \ubc15\ud14c\ub9ac\uc544\ub97c \uc5f0\uad6c\ud574\uc654\ub2e4.<\/p>\n

\uadf8\ub9ac\uace0 \uc774\ub4e4 \ubbf8\uc0dd\ubb3c \uad70\uc774 \ub9e4\uc6b0 \uc815\uad50\ud55c \uc0dd\uccb4\uc2dc\uacc4(biological clock) \uae30\ub2a5\uc744 \uc218\ud589\ud558\uace0 \uc788\uc73c\uba70, \uc774 \uae30\ub2a5\uc744 \ubd84\uc11d\ud560 \uacbd\uc6b0 \uc9c0\uad6c\uc0c1\uc5d0 \uc0b4\uace0 \uc788\ub294 \ubaa8\ub4e0 \uc0ac\ub78c\ub4e4\uc758 \uc0dd\ubb3c\ud559\uc801 \uc5f0\ub839(biological age) \ucd94\uc815\uc774 \uac00\ub2a5\ud558\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\ub2e4.<\/p>\n

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\uacfc\ud559\uc790\ub4e4\uc744 \ud1b5\ud574 \uc7a5 \ubc15\ud14c\ub9ac\uc544\uac00 \uc0dd\uccb4\uc2dc\uacc4 \uae30\ub2a5\uc744 \uc218\ud589\ud558\uace0 \uc788\uc73c\uba70, \uc774 \uae30\ub2a5\uc744 \ubd84\uc11d\ud560 \uacbd\uc6b0 \uc0ac\ub78c\ub4e4\uc758 \uc0dd\ubb3c\ud559\uc801 \uc5f0\ub839\uc744 \uce21\uc815\ud560 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \ubc1c\ud45c\ub410\ub2e4. \u24d2coursesandconferences.wellcomegenomecampus.org<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\u2018\uc778\uc2e4\ub9ac\ucf54 \uba54\ub514\uc2a8\u2019\uc5d0\uc11c\ub294 \ud604\uc7ac \uc774 \ubd84\uc11d \ubc29\uc2dd\uc744 \uc2e4\uc6a9\ud654\ud574 \uc758\ub8cc\uae30\uad00\uc744 \ube44\ub86f, \uc77c\ubc18 \ub300\uc911\uc774 \ud65c\uc6a9\ud560 \uc218 \uc788\ub294 \ubc29\uc548\uc744 \ucc3e\uace0 \uc788\ub294 \uac83\uc744 \uc54c\ub824\uc84c\ub2e4.<\/p>\n

\uc7a5 \ubc15\ud14c\ub9ac\uc544\ub294 \uc18c\ud654\uae30\uad00\uc5d0 \uc0b4\uace0 \uc788\ub294 \ubcf5\uc7a1\ud55c \uad6c\uc870\uc758 \ubbf8\uc0dd\ubb3c \uc9d1\ub2e8\uc744 \ub9d0\ud55c\ub2e4.<\/p>\n

\uc0ac\ub78c \uc548\uc5d0 \uc0b4\uace0 \uc788\ub294 \ubbf8\uc0dd\ubb3c \uad70\uc9d1\uccb4 \uc911 \uac00\uc7a5 \ub9ce\uc740 \uc218\uc758 \ubc15\ud14c\ub9ac\uc544\uc640 \uac00\uc7a5 \ub9ce\uc740 \uc218\uc758 \uc885\uc744 \uac00\uc9c0\uace0 \uc788\uc5b4 \uc778\uccb4 \uac74\uac15\uc5d0 \uac00\uc7a5 \ud070 \uc601\ud5a5\uc744 \ubbf8\uce58\uace0 \uc788\ub2e4.<\/p>\n

\uc5f0\uad6c\ub97c \uc774\ub048 \uc54c\ub809\uc2a4 \uc790\ubcf4\ub860\ucf54\ube0c(Alex Zhavoronkov) \ubc15\uc0ac\uc5d0 \ub530\ub974\uba74 \uc774\uc804\uc758 \uc7a5 \ubc15\ud14c\ub9ac\uc544 \uc5f0\uad6c\ub294 \ub2e4\uc774\uc5b4\ud2b8\uc640 \uad00\ub828\ub41c \uac74\uac15 \uc0c1\ud0dc,\u00a0\ub610\ub294 \ud2b9\uc815\ud55c \uc720\uc804\uc790\uc640 \uad00\ub828\ub41c \uc9c8\ubcd1 \ub4f1 \ubd80\ubd84\uc801\uc778 \uc5f0\uad6c\uc5d0 \uad6d\ud55c\ub3fc\uc654\ub2e4.<\/p>\n

\uc790\ube0c\ub860\ucf54\ube0c \ubc15\uc0ac\ub294 \uc774\ub7f0 \uc0c1\ud669\uc5d0\uc11c \u2018\uc778\uc2e4\ub9ac\ucf54 \uba54\ub514\uc2a8\u2019 \uc5f0\uad6c\ud300\uc774 \uc774\uc804\uacfc \ub2e4\ub978 \uc0c8\ub85c\uc6b4 \uc2dc\ub3c4\ub97c \uc218\ud589\ud588\ub2e4\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n

\uc9c0\uad6c\uc0c1\uc5d0 \uc0b4\uace0 \uc788\ub294 \ub2e4\uc591\ud55c \uc778\uc885\uc744 \ub300\uc0c1\uc73c\ub85c \uc7a5 \ubc15\ud14c\ub9ac\uc544 \ud45c\ubcf8\uc744 \ubd84\uc11d\ud574 \uc0dd\uccb4\uc2dc\uacc4\uc640\uc758 \uc5f0\uad00 \uad00\uacc4\ub97c \ubc1d\ud788\uace0, \ub610\ud55c \uc0dd\ubb3c\ud559\uc801 \uc5f0\ub839\uc744 \ucd94\uc815\ud574\ub0b4\ub294\ub370 \uc131\uacf5\ud588\ub2e4\ub294 \uac83.<\/p>\n

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\uc790\ube0c\ub860\ucf54\ube0c \ubc15\uc0ac \uc5f0\uad6c\ud300\uc740 \uc7a5 \ubc15\ud14c\ub9ac\uc544 \ud45c\ubcf8\uc744 \ubd84\uc11d\ud574 \uc0dd\uccb4\uc2dc\uacc4\uc640\uc758 \uc5f0\uad00 \uad00\uacc4\ub97c \ubc1d\ud788\uace0, \ub610\ud55c \uc0dd\ubb3c\ud559\uc801 \uc5f0\ub839\uc744 \ucd94\uc815\ud574\ub0b4\ub294\ub370 \uc131\uacf5\ud588\ub2e4. \u24d2 Pixabay<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\uc5f0\uad6c \uacb0\uacfc\ub294 \uc0dd\ubb3c\ud559 \ubd84\uc57c \ub17c\ubb38\uc744 \uc628\ub77c\uc778\uc73c\ub85c \uacf5\uac1c\ud558\ub294 \u2018bioRxiv\u2019\uc5d0 \uac8c\uc7ac\ub410\ub2e4. \ub17c\ubb38 \uc81c\ubaa9\uc740 \u2018Human microbiome aging clocks based on deep learning and tandem of permutation feature importance and accumulated local effects\u2019\uc774\ub2e4.<\/p>\n

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\uc778\uc2e4\ub9ac\ucf54 \uba54\ub514\uc2a8, \uc7a5 \ubc15\ud14c\ub9ac\uc544 \ud50c\ub7ab\ud3fc \uad6c\ucd95\u00a0<\/strong><\/p>\n

\uc778\uccb4 \ub0b4\ubd80\uc5d0\ub294 \uc77c\uc885\uc758 \uc2dc\uacc4 \uac19\uc740 \uac83\uc774 \uc788\uc5b4\uc11c \uc2dc\uac04\uc758 \ub530\ub978 \uc778\uccb4\uc758 \uc0dd\uccb4\ub9ac\ub4ec\uc744 \uc8fc\uad00\ud558\ub294\ub370, \uc774\ub97c \uc0dd\uccb4\uc2dc\uacc4\ub77c \ud55c\ub2e4. \ub0ae\uacfc \ubc24\uc758 \uc2dc\uac04 \ubcc0\ud654\uc5d0 \ub530\ub77c \uc218\uba74 \ud328\ud134\uc774 \ub2ec\ub77c\uc9c0\uace0, \uccb4\uc628\uc774 \uc870\uc808\ub418\uba70, \ud608\uc555\uc5d0 \ubcc0\ud654\uac00 \uc77c\uc5b4\ub098\uace0 \uc788\ub294 \uac83 \ub4f1\uc744 \ub9d0\ud55c\ub2e4.<\/p>\n

\uc7a5 \ubc15\ud14c\ub9ac\uc544\uac00 \uc0dd\uccb4\uc2dc\uacc4\uc640 \uad00\ub828\uc774 \uc788\ub2e4\uace0 \ubcf8 \uc5f0\uad6c\ud300\uc740 \uc2dc\uac04\uc5d0 \ub530\ub77c \uc7a5 \ubc15\ud14c\ub9ac\uc544\uac00 \uc5b4\ub5bb\uac8c \ubcc0\ud654\ud558\ub294\uc9c0 \ubd84\uc11d\ud558\uae30 \uc704\ud574 \uc138\uacc4 \uc804\uc5ed\uc5d0 \uac70\uc8fc\ud558\ub294 1165\uba85\uc758 \uc0ac\ub78c\ub4e4\ub85c\ubd80\ud130 3600\uc5ec \ud45c\ubcf8(sample)\uc744 \ucd94\ucd9c\ud588\ub2e4.<\/p>\n

\uadf8\ub9ac\uace0 \ud45c\ubcf8 \ubd84\uc11d\uc744 \ud1b5\ud574 \uc7a5\ub0b4 \ubc15\ud14c\ub9ac\uc544\uc758 \uc720\ud615 \uc911 3\ubd84\uc758 1\uc740 20~39\uc138 \ub098\uc774\uc5d0, 3\ubd84\uc758 1\uc740 40~59\uc138 \ub098\uc774\uc5d0, \ub9c8\uc9c0\ub9c9 3\ubd84\uc758 1\uc740 60~90\uc138 \ub098\uc774\uc5d0 \ud574\ub2f9\ud55c\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uc54c\uc544\ub0c8\ub2e4.<\/p>\n

\uc774\ub294 \uc7a5 \ubc15\ud14c\ub9ac\uc544\uc758 \uc720\ud615\uc774 \ub098\uc774\uc640 \ubc00\uc811\ud55c \uad00\uacc4\uac00 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uc758\ubbf8\ud55c\ub2e4.<\/p>\n

\uc0c8\ub85c\uc6b4 \uc0ac\uc2e4\uc744 \uc811\ud55c \uc5f0\uad6c\ud300\uc740 \uc778\uacf5\uc9c0\ub2a5\uc778 \uba38\uc2e0\ub7ec\ub2dd(machine learning)\uc744 \ud22c\uc785\ud574 \ub2e4\ub974\uac8c \ub098\ud0c0\ub098\uace0 \uc788\ub294 \uc7a5 \ubc15\ud14c\ub9ac\uc544\uc758 \ud2b9\uc9d5\uc774 \ubb34\uc5c7\uc778\uc9c0 \uc815\ubc00 \ubd84\uc11d\uc744 \uc2dc\ub3c4\ud588\ub2e4.<\/p>\n

\uadf8\ub9ac\uace0 90%\uc758 \uc7a5 \ubc15\ud14c\ub9ac\uc544 \ud45c\ubcf8\uc774 95\uac1c\uc758 \ub2e4\ub978 \uc885(\u7a2e)\ub4e4\ub85c \uad6c\uc131\ub3fc \uc788\uc73c\uba70 \uc774 \uc911 39\uc885\uc740 \ub098\uc774\ub97c \ucd94\uc815\ud558\ub294\ub370 \ub9e4\uc6b0 \uc911\uc694\ud55c \uc885\ub4e4\uc774\ub77c\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\ub2e4.<\/p>\n

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\uc5f0\uad6c\ud300\uc740 \uc778\uacf5\uc9c0\ub2a5\uc778 \uba38\uc2e0\ub7ec\ub2dd(machine learning)\uc744 \ud22c\uc785\ud574 \ub2e4\ub974\uac8c \ub098\ud0c0\ub098\uace0 \uc788\ub294 \uc7a5 \ubc15\ud14c\ub9ac\uc544\uc758 \ud2b9\uc9d5\uc774 \ubb34\uc5c7\uc778\uc9c0 \uc815\ubc00 \ubd84\uc11d\uc744 \uc2dc\ub3c4\ud588\ub2e4. \u24d2 Pixabay<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\uc5f0\uad6c\ud300\uc740 \ub098\uba38\uc9c0 10%\uc5d0 \ub300\ud574\uc11c\ub3c4 \ubd84\uc11d\uc744 \uc2dc\ub3c4\ud588\ub2e4. \uadf8\ub9ac\uace0 \ub610 \ub2e4\ub978 \ud2b9\uc9d5\ub4e4\uc744 \ubd84\uc11d\ud574 3.94\ub144\uc758 \uc624\ucc28 \ubc94\uc704 \uc548\uc5d0\uc11c \uc2e4\uc81c \ub098\uc774 \ucd94\uc815\uc774 \uac00\ub2a5\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\ub2e4. \uc790\ube0c\ub860\ucf54\ube0c \ubc15\uc0ac\ub294 3.94\ub144\uc758 \uc624\ucc28\uac00 \uc778\uacf5\uc9c0\ub2a5\uc758 \uad50\ucc28\uac80\uc99d\uc5d0 \ub530\ub978 \uacb0\uacfc\ub77c\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\uc790\ubcf4\ub860\ucf54\ube0c \ubc15\uc0ac \uc5f0\uad6c\ud300\uc774 \ubc1d\ud600\ub0b8 \uac83\uc740 \uc77c\ubd80 \uc7a5 \ubc15\ud14c\ub9ac\uc544\uac00 \ud2b9\uc815 \uc5f0\ub839\uc758 \uc0ac\ub78c\uc5d0\uac8c \ub9ce\uc774 \ubd84\ud3ec\ub3fc \uc788\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n

\uc7a5\ub0b4 \uc2e0\uc9c4\ub300\uc0ac\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc9c4 \u2018\uc720\ubc15\ud14c\ub9ac\uc6c0 \ud560\ub9ac(Eubacterium hallii)\u2019, \uc5fc\uc99d\uc744 \uc77c\uc73c\ud0a4\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc9c4 \u2018\ubc15\ud14c\ub85c\uc774\ub370\uc2a4 \ubd88\uac00\ud22c\uc2a4(Bacteroides vulgatus)\u2019\uc758 \uacbd\uc6b0\uac00 \ub300\ud45c\uc801\uc778 \uc0ac\ub840\ub2e4. \uc5f0\ub839\uc5d0 \ub530\ub77c \uadf8 \uc218\uc5d0 \ud070 \ucc28\uc774\uac00 \uc788\uc5c8\ub2e4.<\/p>\n

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\uc790\ubcf4\ub860\ucf54\ube0c \ubc15\uc0ac \uc5f0\uad6c\ud300\uc774 \ubc1d\ud600\ub0b8 \uac83\uc740 \uc77c\ubd80 \uc7a5 \ubc15\ud14c\ub9ac\uc544\uac00 \ud2b9\uc815 \uc5f0\ub839\uc758 \uc0ac\ub78c\uc5d0\uac8c \ub9ce\uc774 \ubd84\ud3ec\ub3fc \uc788\ub2e4\ub294 \uac83\uc774\ub2e4. \u24d2 Pixabay<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\ub2e4\uc774\uc5b4\ud2b8\ub97c \ud558\uace0 \uc788\ub2e4\ub4e0\uc9c0 \uc7a0\uc790\ub294 \uc2b5\uad00, \uadf8\ub9ac\uace0 \uc721\uccb4\uc801\uc778 \ud65c\ub3d9\ub7c9 \ub4f1\ub3c4 \uc7a5 \ubc15\ud14c\ub9ac\uc544 \uc885(\u7a2e) \ubd84\ud3ec\ub3c4\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4.<\/p>\n

\uc790\ubcf4\ub860\ucf54\ube0c \ubc15\uc0ac\ub294 \u201c\uc7a5 \ubc15\ud14c\ub9ac\uc544 \ud65c\ub3d9\ub7c9\uc744 \ubd84\uc11d\ud574 \uc0dd\uccb4 \ub9ac\ub4ec\uc744 \uce21\uc815\ud560 \uc218 \uc788\uc73c\uba70, \ub098\uc774\uc640\uc758 \uc5f0\uad00\uad00\uacc4\ub97c \ucd94\uc815\ud574\ub098\uac00\uba74\uc11c \uac1c\uc778\ubcc4 \uac74\uac15\uc0c1\ud0dc\ub97c \ucd94\uc815\ud560 \uc218 \uc788\uc5b4 \uac1c\uc778 \uac04 \uac74\uac15\uc0c1\ud0dc\ub97c \ube44\uad50\ud574\ub098\uac08 \uc218 \uc788\ub2e4.\u201d\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n

\ubc15\uc0ac\ub294 \u201c\uc774\ubc88 \uc5f0\uad6c \uacb0\uacfc\ub85c \uc9c0\uad6c\uc0c1\uc5d0 \uc0b4\uace0 \uc788\ub294 \ub2e4\uc591\ud55c \uc778\uc885\uc744 \ub300\uc0c1\uc73c\ub85c \uc0dd\uccb4\uc2dc\uacc4\ub97c \uce21\uc815\ud558\uace0, \ub610\ud55c \uc0dd\ubb3c\ud559\uc801 \ub098\uc774\ub97c \ucd94\uc815\ud558\ub294 \uc77c\uc774 \uac00\ub2a5\ud574\uc84c\ub2e4.\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\uadf8\ub294 \ub610 \u201c\uc0dd\uba85\uacf5\ud559 \uae30\uc5c5\uc778 \u2018\uc778\uc2e4\ub9ac\ucf54 \uba54\ub514\uc2a8\u2019\uc744 \ud1b5\ud574 \uac1c\uc778\ubcc4\ub85c \uc11c\ub85c \ub2e4\ub974\uac8c \ub098\ud0c0\ub098\ub294 \uc7a5 \ubc15\ud14c\ub9ac\uc544 \uc0c1\ud669\uc744 \ubaa8\ub378\ud654\ud574 \uc138\uacc4\uc801\uc73c\ub85c \ub204\uad6c\ub098 \ucc38\uc5ec\ud560 \uc218 \uc788\ub294 \uac74\uac15 \uc5f0\ub839 \ud574\uc11d\uc774 \uac00\ub2a5\ud55c \ud50c\ub7ab\ud3fc\uc744 \uad6c\ucd95\ud558\uaca0\ub2e4.\u201d\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\u201c\uc774 \ud50c\ub7ab\ud3fc\uc744 \ud1b5\ud574 \uc81c\uc2dc\ub418\ub294 \ub370\uc774\ud130\ub294 95\uc885\uc758 \uc7a5 \ubc15\ud14c\ub9ac\uc544 \uad00\ub828 \ub370\uc774\ud130\ub97c \ud1b5\ud574 \uad6c\ucd95\ub41c \ucd5c\ucd08\uc758 \uc0dd\uccb4\uc9c0\ud45c(biomarkers)\uac00 \ub420 \uac83\u201d\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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(\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

    [\uc694\uc57d]\u00a0\uc2a4\uc704\uc2a4 \ub85c\uc794\uc5f0\ubc29\uacf5\uacfc\ub300\ud559(EPFL)\u00a0\uacfc\ud559\uc790\ub4e4\uc740 \uba74\uc5ed\uacc4\uc758 \uae30\ub2a5\uc7a5\uc560\uac00 \uc5b4\ub5bb\uac8c \uc7a5\ub0b4 \uc138\uade0\uc758 \uacfc\ubd80\ud558\ub97c \uc720\ubc1c\uc2dc\ud0a4\ub294\uc9c0 \ubc1c\uacac\ud588\ub2e4.\u00a0\uc138\uade0\uc740 \uacfc\ub3c4\ud55c \uc816\uc0b0\uc744 \ub9cc\ub4e4\uc5b4\ub0b4\uace0 \uc138\ud3ec \uc190\uc0c1\uacfc \ub178\ud654\uad00\ub828 \uc9c8\ud658\uc744 \uc720\ubc1c\uc2dc\ud0a4\ub294 \ud65c\uc131\uc0b0\uc18c \uc0dd\uc131\uc744 \uc720\ubc1c\uc2dc\ud0a4\uac8c \ub41c\ub2e4. (2018.11)(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[44,38,33,29],"tags":[],"class_list":["post-3028","post","type-post","status-publish","format-standard","hentry","category-10------11--","category-38","category-do-biology","category-lets-do-science"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t