{"id":2954,"date":"2019-03-27T13:19:18","date_gmt":"2019-03-27T04:19:18","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=2954"},"modified":"2019-03-27T13:19:18","modified_gmt":"2019-03-27T04:19:18","slug":"hidden-flaws-in-common-piece-of-lab-kit-could-botch-experiments","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2954","title":{"rendered":"Hidden flaws in common piece of lab kit could botch experiments"},"content":{"rendered":"<p>&nbsp;<\/p>\n<h5>Well-used magnetic stirrers harbour metal atoms that could bias the results of chemical and biochemical reactions.<\/h5>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"figure__image\" src=\"https:\/\/media.nature.com\/w700\/magazine-assets\/d41586-019-00980-7\/d41586-019-00980-7_16573222.jpg\" alt=\"Four beakers containing blue liquid and spinning magnetic stirrer bars in a lab\" data-src=\"\/\/media.nature.com\/w700\/magazine-assets\/d41586-019-00980-7\/d41586-019-00980-7_16573222.jpg\" \/><\/p>\n<p class=\"figure__caption sans-serif\">Magnetic stirring bars are ubiquitous in research labs, but the bars accumulate damage over time that could muddy experimental results. Credit: Getty<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div class=\"article-item__body serif\">\n<p>The rapidly whirling magnets used to stir mixtures in laboratories the world over can carry contaminants that confound experimental results.<\/p>\n<p>Stirring bars \u2014 little magnetic beads coated in plastic \u2014 are often used for months or years. Valentine Ananikov and his colleagues at the Zelinsky Institute of Organic Chemistry in Moscow scanned bars with an electron microscope to investigate the effects of these long periods of use. They found that the bars\u2019 polytetrafluoroethylene coating developed cracks, dents and scrapes. Worse still, those flaws trapped metal atoms and carried them from one experiment to another.<\/p>\n<p>Routine cleaning of the stirring bars didn\u2019t help. The researchers looked at 60 beads from various laboratories, and found only one that was free of contamination. Among the contaminants were palladium, platinum and gold, all of which can act as catalysts to speed up chemical reactions.<\/p>\n<p>In tests, brand new stirring bars did not affect reactions, but used bars had unpredictable effects that probably depended on the nature and amount of contamination. The authors recommend using fresh beads to get the best results if avoiding contamination is important.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<div class=\"article__sidebar\">\n<p class=\"article-item__original-research strong\"><a class=\"serif\" href=\"https:\/\/doi.org\/10.1021\/acscatal.9b00294\" data-track=\"click\" data-track-label=\"original research\"><i>Am. Chem. Soc. Catal.<\/i>\u00a0(2019)<\/a><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>(\uc6d0\ubb38: <a href=\"https:\/\/www.nature.com\/articles\/d41586-019-00980-7?utm_source=feedburner&amp;utm_medium=feed&amp;utm_campaign=Feed%3A+nature%2Frss%2Fcurrent+%28Nature+-+Issue%29\">\uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Well-used magnetic stirrers harbour metal atoms that could bias the results of chemical and biochemical reactions. &nbsp; Magnetic stirring bars are ubiquitous in research<a href=\"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2954\" class=\"more-link\">(more&#8230;)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[32,34,29,30],"tags":[],"class_list":["post-2954","post","type-post","status-publish","format-standard","hentry","category-essays-on-science","category-lets-do-chemistry","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"Well-used magnetic stirrers harbour metal atoms that could bias the results of chemical and biochemical reactions. 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Magnetic stirring bars are ubiquitous in research labs, but the bars accumulate damage over time that could muddy experimental results. Credit: Getty The rapidly whirling magnets used to stir mixtures in laboratories the world","og:url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2954","og:image":"https:\/\/biochemistry.khu.ac.kr\/lab\/wp-content\/uploads\/2018\/06\/cropped-logoKHU-1-2.png","og:image:secure_url":"https:\/\/biochemistry.khu.ac.kr\/lab\/wp-content\/uploads\/2018\/06\/cropped-logoKHU-1-2.png","og:image:width":66,"og:image:height":46,"article:published_time":"2019-03-27T04:19:18+00:00","article:modified_time":"2019-03-27T04:19:18+00:00","twitter:card":"summary_large_image","twitter:title":"Hidden flaws in common piece of lab kit could botch experiments \u2014 Synthesis-Based BioFusion Technology Lab","twitter:description":"Well-used magnetic stirrers harbour metal atoms that could bias the results of chemical and biochemical reactions. 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However, the ability to selectively activate CRISPR-Cas systems in diseased cells is important to ensure that gene editing only occurs where it is wanted. Zhu\u00a0et al.\u00a0developed a\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3881,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3881","url_meta":{"origin":2954,"position":1},"title":"Caging cells in functional shells","author":"biochemistry","date":"July 16, 2019","format":false,"excerpt":"\u00a0 \u00a0 Unprotected cells are sensitive to changes in their environment, including temperature, pH, and osmotic pressure. Zhu\u00a0et al.\u00a0have developed a facile route to encapsulating mammalian cells inside functional nanoparticles. A range of nanoparticles, encompassing several types of metal-organic frameworks, mesoporous silica, and iron oxide, were mixed with interparticle ligands\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3568,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3568","url_meta":{"origin":2954,"position":2},"title":"Superconductivity near room temperature","author":"biochemistry","date":"May 23, 2019","format":false,"excerpt":"\u00a0 \u00a0 For a century, researchers have sought materials that superconduct \u2014 transport electricity without loss \u2014 at room temperature. Experimental data now confirm superconductivity at higher temperatures than ever before. \u00a0 Materials known as superconductors transmit electrical energy with 100% efficiency. They have a wide range of applications, such\u2026","rel":"","context":"In &quot;Let's Do Chemistry!&quot;","block_context":{"text":"Let's Do Chemistry!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=34"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3255,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3255","url_meta":{"origin":2954,"position":3},"title":"All for one and one for all (QUANTUM OPTICS)","author":"biochemistry","date":"April 8, 2019","format":false,"excerpt":"\u00a0 \u00a0 Quantum information (QI) has become a focus of research during the past two decades, with the goal of exploiting the potentialities offered by superposition and entanglement of quantum states (1). The first hardware implementations of QI relied on quantum systems hosting clean, well-isolated two-level systems such as atoms\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":464,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=464","url_meta":{"origin":2954,"position":4},"title":"Battery\uc758 \uc6d0\ub9ac, \uae30\ubcf8\uc744 \ud30c\ud5e4\uce58\uc790 &#8211; \uc804\uae30\ud654\ud559 \uae30\ucd08\ud3b8","author":"biochemistry","date":"May 30, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0","rel":"","context":"In &quot;Let's Do Chemistry!&quot;","block_context":{"text":"Let's Do Chemistry!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=34"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/163.180.4.195\/wp\/wp-content\/uploads\/2018\/05\/1-180x300.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1821,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1821","url_meta":{"origin":2954,"position":5},"title":"Reimagining of Schr\u00f6dinger\u2019s cat breaks quantum mechanics \u2014 and stumps physicists","author":"biochemistry","date":"September 23, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) \u00a0 \u00a0 In a multi-\u2018cat\u2019 experiment, the textbook interpretation of quantum theory seems to lead to contradictory pictures of reality, physicists claim. \u00a0 \u00a0 Credit: Aleksei Isachenko\/Alamy \u00a0 \u00a0 In the world\u2019s most famous thought experiment, physicist Erwin Schr\u00f6dinger described how a cat in a\u2026","rel":"","context":"In &quot;Let's Do Chemistry!&quot;","block_context":{"text":"Let's Do Chemistry!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=34"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p9Xo1j-LE","_links":{"self":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2954"}],"version-history":[{"count":1,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2954\/revisions"}],"predecessor-version":[{"id":2955,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2954\/revisions\/2955"}],"wp:attachment":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}