{"id":2793,"date":"2019-03-07T17:24:27","date_gmt":"2019-03-07T08:24:27","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=2793"},"modified":"2023-07-05T14:30:28","modified_gmt":"2023-07-05T05:30:28","slug":"converting-light-into-atp","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2793","title":{"rendered":"Converting light into ATP"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>(\uc6d0\ubb38: <a href=\"https:\/\/doi.org\/10.1002\/ange.201813963\">\uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n<div class=\"pl20 mq875-pl0 serif\">\n<p><i>Angew. Chem<\/i>. (2019).<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<div class=\"pl20 mq875-pl0 serif\">\n<p>Artificial cells are compartmentalized structures that can mimic essential functions of their biological counterpart. They have been useful to understand and recreate minimalistic metabolic pathways and the structure of protocells. Now, Chen and co-workers report artificial cells that can convert light into biochemical energy in the form of adenosine triphosphate (ATP). The system is composed of two artificial cells, one that converts light into a proton gradient and one that converts this gradient into ATP.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<div class=\"pl20 mq875-pl0 serif\">\n<p>To convert light into a proton gradient, the researchers self-assemble an artificial cell made of packed Au\u2013Ag nanorods with an embedded bacteriorhodopsin. The nanorods induce a preferential orientation of the bacteriorhodopsin. As a result, on irradiation, the bacteriorhodopsin pumps protons from inside the artificial cell to the bulk solution. At the steady state, the system can achieve a pH difference of 0.52. The effect is due to coupling between the plasmon resonance of the Au\u2013Ag nanorods and that of rhodopsin. A second artificial cell containing an ATP synthase within a lipidic membrane uses the difference in proton concentration now existing between the outside and inside compartments to drive the synthesis of ATP molecules.<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>(\uc6d0\ubb38: <a href=\"https:\/\/www.nature.com\/articles\/s41565-019-0408-z?utm_source=feedburner&amp;utm_medium=feed&amp;utm_campaign=Feed%3A+nnano%2Frss%2Fcurrent+%28Nature+Nanotechnology+-+Issue%29\">\uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) Angew. Chem. (2019). &nbsp; &nbsp; Artificial cells are compartmentalized structures that can mimic essential functions of their biological counterpart. They<a href=\"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2793\" class=\"more-link\">(more&#8230;)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[33,34,29,30],"tags":[],"class_list":["post-2793","post","type-post","status-publish","format-standard","hentry","category-do-biology","category-lets-do-chemistry","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"(\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) Angew. 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Chem. (2019). Artificial cells are compartmentalized structures that can mimic essential functions of their biological counterpart. They have been useful to understand and recreate minimalistic metabolic pathways and the structure of protocells. Now, Chen and co-workers report artificial cells that can convert light into biochemical energy in","og:url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2793","og:image":"https:\/\/biochemistry.khu.ac.kr\/lab\/wp-content\/uploads\/2018\/06\/cropped-logoKHU-1-2.png","og:image:secure_url":"https:\/\/biochemistry.khu.ac.kr\/lab\/wp-content\/uploads\/2018\/06\/cropped-logoKHU-1-2.png","og:image:width":66,"og:image:height":46,"article:published_time":"2019-03-07T08:24:27+00:00","article:modified_time":"2023-07-05T05:30:28+00:00","twitter:card":"summary_large_image","twitter:title":"Converting light into ATP \u2014 Synthesis-Based BioFusion Technology Lab","twitter:description":"(\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) Angew. Chem. (2019). Artificial cells are compartmentalized structures that can mimic essential functions of their biological counterpart. They have been useful to understand and recreate minimalistic metabolic pathways and the structure of protocells. 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Reactions in organelles have been recapitulated\u00a0in vitro\u00a0by reconstituting functional protein machineries into membrane systems3,4,5. However, maintaining\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2250,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2250","url_meta":{"origin":2793,"position":1},"title":"Artificial cells gain communication skills","author":"biochemistry","date":"December 3, 2018","format":false,"excerpt":"\u00a0 \u00a0 No biologist would mistake the microscopic \u201ccells\u201d that chemical biologist Neal Devaraj and colleagues are whipping up at the University of California, San Diego (UCSD), for the real thing. Instead of the lipid membrane that swaddles our cells, these cell mimics wear a coat of plastic\u2014polymerized acrylate. 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The real-time analysis and perturbation of living cells would generate a step change in single-cell analysis.\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2722,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2722","url_meta":{"origin":2793,"position":3},"title":"Why neutrons and protons are modified inside nuclei","author":"biochemistry","date":"February 22, 2019","format":false,"excerpt":"\u00a0 \u00a0 The structure of a neutron or a proton is modified when the particle is bound in an atomic nucleus. Experimental data suggest an explanation for this phenomenon that could have broad implications for nuclear physics. \u00a0 In 1983, it was discovered that the internal structure of a nucleon\u2026","rel":"","context":"In &quot;Let's Do Chemistry!&quot;","block_context":{"text":"Let's Do Chemistry!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=34"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":4961,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=4961","url_meta":{"origin":2793,"position":4},"title":"Powerful antibiotics discovered using AI","author":"biochemistry","date":"February 24, 2020","format":false,"excerpt":"\u00a0 Machine learning spots molecules that work even against \u2018untreatable\u2019 strains of bacteria. \u00a0 \u00a0 Escherichia coli\u00a0bacteria, coloured green, in a scanning electron micrograph.Credit: Stephanie Schuller\/SPL \u00a0 \u00a0 A pioneering machine-learning approach has identified powerful new types of antibiotic from a pool of more than 100 million molecules \u2014 including\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":4788,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=4788","url_meta":{"origin":2793,"position":5},"title":"Next-generation artificial vision comes into view","author":"biochemistry","date":"November 8, 2019","format":false,"excerpt":"\u00a0 \u00a0 A grid of photodiodes as wide as a sesame seed rests in the eye of a person with macular degeneration. 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