{"id":2681,"date":"2019-02-20T12:18:31","date_gmt":"2019-02-20T03:18:31","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=2681"},"modified":"2019-02-20T12:18:31","modified_gmt":"2019-02-20T03:18:31","slug":"the-giant-medusavirus-turns-defenceless-cells-to-stone","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2681","title":{"rendered":"The giant Medusavirus turns defenceless cells to \u2018stone\u2019"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h4 class=\"article-item__teaser-text serif\">Novel virus extracted from a hot spring bears thousands of unique spikes.<\/h4>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"figure__image\" src=\"https:\/\/media.nature.com\/w700\/magazine-assets\/d41586-019-00591-2\/d41586-019-00591-2_16487572.jpg\" alt=\"3D reconstruction of the Medusavirus particle\" data-src=\"\/\/media.nature.com\/w700\/magazine-assets\/d41586-019-00591-2\/d41586-019-00591-2_16487572.jpg\" \/><\/p>\n<p class=\"figure__caption sans-serif\">A 3D reconstruction of the Medusavirus particle showcases its thousands of external spikes, which protrude roughly 14 nanometres from the particle\u2019s surface. Credit: G. Yoshikawa\u00a0<i>et al.<\/i>\/<i>J. Virol.<\/i>\u00a0(CC BY 4.0)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div class=\"article-item__body serif\">\n<p>A microscopic behemoth that can turn amoebae into stone-like cysts is shaking up the virus family tree. Scientists have named it the Medusavirus.<\/p>\n<p>A team of researchers led by Masaharu Takemura at Tokyo University of Science and Hiroyuki Ogata at Kyoto University in Japan isolated the giant virus from a sample of mud and dead leaves collected from a Japanese hot spring. The scientists then mixed the virus with hundreds of amoebae called\u00a0<i>Acanthamoeba castellanii<\/i>.<\/p>\n<p>The virus infected the amoebae and multiplied inside them, causing some to burst. Other amoebae developed a hard shell, prompting the researchers to name the virus after Medusa, the Greek mythological monster who turned onlookers to stone. On closer examination, the scientists determined that the virus\u2019s genetic material is protected by 2,660 spherical-headed spikes.<\/p>\n<p>The strange findings led the researchers to propose that the virus receive its own taxonomic family:\u00a0<i>Medusaviridae<\/i>.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<div class=\"article__sidebar\">\n<p class=\"article-item__original-research strong\"><a class=\"serif\" href=\"https:\/\/doi.org\/10.1128\/JVI.02130-18\" data-track=\"click\" data-track-label=\"original research\"><i>J. Virol.<\/i>\u00a0(2019)<\/a><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>(\uc6d0\ubb38: <a href=\"https:\/\/www.nature.com\/articles\/d41586-019-00591-2?utm_source=feedburner&amp;utm_medium=feed&amp;utm_campaign=Feed%3A+nature%2Frss%2Fcurrent+%28Nature+-+Issue%29\">\uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; Novel virus extracted from a hot spring bears thousands of unique spikes. &nbsp; A 3D reconstruction of the Medusavirus particle showcases its thousands<a href=\"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2681\" class=\"more-link\">(more&#8230;)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[33,29,30],"tags":[],"class_list":["post-2681","post","type-post","status-publish","format-standard","hentry","category-do-biology","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":955,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=955","url_meta":{"origin":2681,"position":0},"title":"How cells imprison viruses in molecular cages","author":"biochemistry","date":"June 25, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 \u00a0 Vaccinia virus particles (pictured) can be immobilized \u2014 at least temporarily \u2014 by host cells. Credit: Dr Klaus Boller\/SPL How cells imprison viruses in molecular cages Corralled viruses escape by co-opting cellular proteins. \u00a0 A protein cage that cells deploy to slow the spread\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":4720,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=4720","url_meta":{"origin":2681,"position":1},"title":"Measles erases immune \u2018memory\u2019 for other diseases &#038; How measles causes the body to \u2018forget\u2019 past infections","author":"biochemistry","date":"November 2, 2019","format":false,"excerpt":"\u00a0 Results from tests of unvaccinated children and monkeys come as measles cases spike around the world. \u00a0 \u00a0 Children with measles receive care in a hospital in the Philippines.Credit: Ezra Acayan\/Getty \u00a0 \u00a0 Measles infections in children can wipe out the immune system\u2019s memory of other illnesses such as\u00a0influenza,\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":404,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=404","url_meta":{"origin":2681,"position":2},"title":"Cancer-killing viruses show promise \u2014 and draw billion-dollar investment","author":"biochemistry","date":"May 30, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 Encouraging trial results spur interest from researchers and drug giants. \u00a0 \u00a0 Researchers are trying to boost the effectiveness of cancer-killing viruses to treat conditions including brain tumours (red).Credit: Sherbrooke Connectivity Imaging Lab\/SPL \u00a0 Pharmaceutical giant Johnson & Johnson announced on 2 May that it\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":4971,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=4971","url_meta":{"origin":2681,"position":3},"title":"Coronavirus epidemic snarls science worldwide","author":"biochemistry","date":"February 24, 2020","format":false,"excerpt":"\u00a0 \u00a0 Like most universities in China, the campus of Huazhong University of Science and Technology in Wuhan is deserted. PHOTO: STRINGER\/GETTY IMAGES \u00a0 \u00a0 The coronavirus epidemic now racing across China is forcing Jeffrey Erlich, a Canadian neuroscientist at New York University Shanghai, to weigh his science against concern\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3809,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3809","url_meta":{"origin":2681,"position":4},"title":"The secret social lives of viruses","author":"biochemistry","date":"June 19, 2019","format":false,"excerpt":"\u00a0 \u00a0 Scientists are listening in on the ways viruses communicate and cooperate. Decoding what the microbes are saying could be a boon to human health. \u00a0 \u00a0 Illustration by Karol Banach \u00a0PDF version \u00a0 \u00a0 Geneticist Rotem Sorek could see that his bacteria were sick \u2014 so far, so\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2977,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2977","url_meta":{"origin":2681,"position":5},"title":"Virus tricks the immune system into ignoring bacterial infections","author":"biochemistry","date":"March 29, 2019","format":false,"excerpt":"\u00a0 \u00a0 \u00a0 The finding could explain why the body tolerates some microbes \u2015 and lead to better treatments for chronic infections. \u00a0 \u00a0 Pseudomonas aeruginosa\u00a0bacteria can be responsible for persistent infections in wounds such as bedsores.\u00a0Credit: James Cavallini\/Science Photo Library \u00a0 \u00a0 A bacterium which is responsible for about\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p9Xo1j-Hf","_links":{"self":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2681","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2681"}],"version-history":[{"count":1,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2681\/revisions"}],"predecessor-version":[{"id":2682,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2681\/revisions\/2682"}],"wp:attachment":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2681"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2681"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2681"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}