{"id":2441,"date":"2019-01-07T14:58:27","date_gmt":"2019-01-07T05:58:27","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=2441"},"modified":"2019-01-07T14:58:27","modified_gmt":"2019-01-07T05:58:27","slug":"nature-biotechs-top-stories-of-the-year","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2441","title":{"rendered":"Nature Biotech&#8217;s top stories of the year"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h4>See what grabbed our readers in 2018. It was a year when CRISPR-ed plants, therapies and babies stole the headlines, but there are also some surprises on this list.<\/h4>\n<p>&nbsp;<\/p>\n<div class=\"article__body serif cleared\">\n<figure class=\"figure\">\n<div class=\"embed intensity--medium\">\n<div class=\"embed intensity--medium\"><img decoding=\"async\" class=\"figure__image\" src=\"https:\/\/media.nature.com\/w800\/magazine-assets\/d41587-019-00001-y\/d41587-019-00001-y_16343022.jpg\" alt=\"\" data-src=\"\/\/media.nature.com\/w800\/magazine-assets\/d41587-019-00001-y\/d41587-019-00001-y_16343022.jpg\" \/><\/div>\n<\/div><figcaption>\n<p class=\"figure__caption sans-serif\"><span class=\"mr10\"><i>While the world\u2019s attention focused on claims of custom babies using CRISPR, Editas received approval to test a gene-editing drug in people.<\/i><\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><\/h4>\n<\/figcaption><\/figure>\n<p>1<a href=\"https:\/\/www.nature.com\/articles\/d41587-018-00003-2\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41587-018-00003-2\" data-track-category=\"body text link\">. Go-ahead for first in-body CRISPR medicine testing<\/a><\/p>\n<p>2.\u00a0<a href=\"https:\/\/rdcu.be\/bfoF2\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoF2\" data-track-category=\"body text link\">T cells fingered as culprits for narcolepsy<\/a><\/p>\n<p>3.\u00a0<a href=\"https:\/\/rdcu.be\/bfoHO\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoHO\" data-track-category=\"body text link\">With a free pass, CRISPR-edited plants reach market in record time<\/a><\/p>\n<p>4.\u00a0<a href=\"https:\/\/rdcu.be\/bfoIb\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoIb\" data-track-category=\"body text link\">Preprint wipes millions off CRISPR companies\u2019 stocks<\/a><\/p>\n<p>5.\u00a0<a href=\"https:\/\/rdcu.be\/bfoIu\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoIu\" data-track-category=\"body text link\">Smart insulin: redesign could end hypoglycemia risk<\/a><\/p>\n<p>6.\u00a0<a href=\"https:\/\/rdcu.be\/bfoIG\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoIG\" data-track-category=\"body text link\">FDA warns public of dangers of DIY gene therapy<\/a><\/p>\n<p>7.\u00a0<a href=\"https:\/\/rdcu.be\/bfoIZ\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoIZ\" data-track-category=\"body text link\">First edible cottonseed go-ahead<\/a><\/p>\n<p>8.\u00a0<a href=\"https:\/\/rdcu.be\/bfoI5\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoI5\" data-track-category=\"body text link\">FDA backs clinician-free AI imaging diagnostic tools<\/a><\/p>\n<p>9.\u00a0<a href=\"https:\/\/rdcu.be\/bfoJw\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoJw\" data-track-category=\"body text link\">Sangamo\u2019s landmark genome editing trial gets mixed reception<\/a><\/p>\n<p>10.\u00a0<a href=\"https:\/\/rdcu.be\/bfoJK\" data-track=\"click\" data-label=\"https:\/\/rdcu.be\/bfoJK\" data-track-category=\"body text link\">CD47 checkpoint data supercharge Stanford spinout IPO<\/a><\/p>\n<\/div>\n<div class=\"emphasis\"><\/div>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>(\uc6d0\ubb38: <a href=\"https:\/\/www.nature.com\/articles\/d41587-019-00001-y?utm_source=feedburner&amp;utm_medium=feed&amp;utm_campaign=Feed%3A+nbt%2Frss%2Fcurrent+%28Nature+Biotechnology+-+Issue%29\">\uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; See what grabbed our readers in 2018. It was a year when CRISPR-ed plants, therapies and babies stole the headlines, but there are<a href=\"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2441\" class=\"more-link\">(more&#8230;)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[32,29,30],"tags":[],"class_list":["post-2441","post","type-post","status-publish","format-standard","hentry","category-essays-on-science","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":3988,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3988","url_meta":{"origin":2441,"position":0},"title":"The long shadow of a CRISPR scandal","author":"biochemistry","date":"August 3, 2019","format":false,"excerpt":"\u00a0 He Jiankui's controversial gene-editing experiment brought intense scrutiny to CRISPR scientists in China, and they're outraged. \u00a0 As He Jiankui strode to the podium at last year's summit on human genome editing in Hong Kong, China, more than 1 million people watched online. PHOTO: ANTHONY WALLACE\/AFP\/GETTY IMAGES \u00a0 \u00a0\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":976,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=976","url_meta":{"origin":2441,"position":1},"title":"CRISPR with a heart of gold helps ailing mice","author":"biochemistry","date":"June 28, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 \u00a0 Gene-editing molecules ride gold nanoparticles into the brain. \u00a0 Expression of a protein (blue-green, left) associated with fragile X syndrome is suppressed (right) in the brains of mice treated with CRISPR gene-editing molecules. Credit: B. Lee\u00a0et al.\/Nature\u00a0Biomed. Eng. \u00a0 \u00a0 Scientists are mining gold\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3992,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3992","url_meta":{"origin":2441,"position":2},"title":"China&#8217;s CRISPR revolution","author":"biochemistry","date":"August 3, 2019","format":false,"excerpt":"\u00a0 \u00a0 Editing of plant, animal, and human genomes has never been easier, as this country's scientists are rapidly demonstrating. \u00a0 FOR MANY PEOPLE, CRISPR plus China equals the biophysicist He Jiankui, who infamously used the genome editor last year to alter the DNA of two human embryos that would\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":4118,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=4118","url_meta":{"origin":2441,"position":3},"title":"CRISPR-mediated live imaging of genome editing and transcription","author":"biochemistry","date":"September 23, 2019","format":false,"excerpt":"\u00a0 \u00a0 Tracking nucleic acids in living cells Fluorescence in situ hybridization (FISH) is a powerful molecular technique for detecting nucleic acids in cells. However, it requires cell fixation and denaturation. Wang\u00a0et al.\u00a0found that CRISPR-Cas9 protects guide RNAs from degradation in cells only when bound to target DNA. Taking advantage\u2026","rel":"","context":"In &quot;Let's Do Biology!&quot;","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3895,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3895","url_meta":{"origin":2441,"position":4},"title":"CRISPR patent fight revived","author":"biochemistry","date":"July 16, 2019","format":false,"excerpt":"\u00a0 \u00a0 A surprise ruling last week reignited the high-profile patent fight over who invented a key application of the genome editor CRISPR. The 3-year-old battle pits parties represented by the University of California (UC) against the Broad Institute in Cambridge, Massachusetts. It revolves around the use of CRISPR, originally\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3986,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3986","url_meta":{"origin":2441,"position":5},"title":"The CRISPR animal kingdom","author":"biochemistry","date":"August 3, 2019","format":false,"excerpt":"\u00a0 \u00a0 China has used the genome editor more aggressively, on more species, than any other country. \u00a0 After using CRISPR to edit a gene that disrupts circadian rhythms in a monkey, Chinese researchers then produced five clones. PHOTO: XINHUA\/INSTITUTE OF NEUROSCIENCE\/CHINESE ACADEMY OF SCIENCES\/REDUX \u00a0 \u00a0 Early one February\u2026","rel":"","context":"In &quot;Essays on Science&quot;","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p9Xo1j-Dn","_links":{"self":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2441"}],"version-history":[{"count":1,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2441\/revisions"}],"predecessor-version":[{"id":2442,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/2441\/revisions\/2442"}],"wp:attachment":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2441"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2441"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}