{"id":2237,"date":"2018-12-03T16:33:46","date_gmt":"2018-12-03T07:33:46","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=2237"},"modified":"2018-12-03T16:33:46","modified_gmt":"2018-12-03T07:33:46","slug":"industry-is-more-alarmed-about-reproducibility-than-academia","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2237","title":{"rendered":"Industry is more alarmed about reproducibility than academia"},"content":{"rendered":"

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The reproducibility crisis in biomedical science seems to have alarmed industry more than the academic community (see\u00a0C. G. Begley and L. M. Ellis\u00a0Nature\u00a0<\/i>483<\/b>, 531\u2013533; 2012<\/a>). In our view, this is because they have different yardsticks for success in research.<\/p>\n

Despite the advent of important new therapeutics, the number of innovative treatments reaching the patient is disappointingly low. To help rectify this, industry is investing in drug-discovery alliances with peers and academic groups, and in precision medicine. It sees high standards of research quality as the route to the most promising drug candidates and to maximum return on investment.<\/p>\n

By contrast, academic scientists may be reluctant to devote extra time and effort to confirming research results in case they fail. That would put paid to publication in high-impact journals, damage career opportunities and curtail further funding. Evidence of questionable practices such as selective publishing and cherry-picking of data indicates that rigour is not always a high priority.<\/p>\n

Paradoxically, the impact of high standards on research objectives is different in industry and in academia. If ignored, this paradox could endanger future collaborations between scientists in the private and public sectors.<\/p>\n<\/div>\n

Nature<\/span>\u00a0563<\/strong>, 626 (2018)<\/p>\n

doi: 10.1038\/d41586-018-07549-w<\/div>\n<\/div>\n

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\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~<\/p>\n

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    The reproducibility crisis in biomedical science seems to have alarmed industry more than the academic community (see\u00a0C. G. Begley and L. M. Ellis\u00a0Nature\u00a0483,(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[32,29,30],"tags":[],"class_list":["post-2237","post","type-post","status-publish","format-standard","hentry","category-essays-on-science","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":3534,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3534","url_meta":{"origin":2237,"position":0},"title":"Companies persist with biomedical papers","author":"biochemistry","date":"May 16, 2019","format":false,"excerpt":"\u00a0 Corporate research in the life sciences endures, despite diminishing in other fields of science. \u00a0 Many advanced countries struggle to increase their productivity. Between 1970 and 2014, real GDP per hour worked, a measure of labour productivity, grew by an average of just 1.62% per year in the United\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3493,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3493","url_meta":{"origin":2237,"position":1},"title":"Brazilian biomedical science faces reproducibility test","author":"biochemistry","date":"May 10, 2019","format":false,"excerpt":"\u00a0 \u00a0 Researchers at more than 60 Brazilian labs will assess the replicability of research by their country\u2019s scientists. \u00a0 An ambitious project to test the reproducibility of biomedical experiments by Brazilian scientists is about to get under way. The Brazilian Reproducibility Initiative was launched last year by researchers at\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3627,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3627","url_meta":{"origin":2237,"position":2},"title":"Reproducibility trial publishes two conclusions\ufeff for one paper","author":"biochemistry","date":"June 5, 2019","format":false,"excerpt":"\u00a0 \u00a0 The\u00a0British\u00a0Journal of Anaesthesia\u2019s unusual experiment is designed to broaden replicability efforts beyond just methods and results. \u00a0 \u00a0 Anaesthesia has been linked to delirium and death in older patients.Credit: BSIP\/UIG via Getty \u00a0 \u00a0 How deeply an anaesthetist should sedate an elderly person when they have surgery is\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1480,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1480","url_meta":{"origin":2237,"position":3},"title":"High-profile journals put to reproducibility test","author":"biochemistry","date":"August 28, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 Researchers replicated 62% of social-behaviour findings published in\u00a0Science\u00a0and\u00a0Nature\u00a0\u2014 a result matched almost exactly by a prediction market. \u00a0 \u00a0 A reproducibility effort has put high-profile journals under the spotlight by trying to replicate a slew of social-science results. In the work, published on 27 August\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":2264,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2264","url_meta":{"origin":2237,"position":4},"title":"Confronting conflict of interest","author":"biochemistry","date":"December 4, 2018","format":false,"excerpt":"\u00a0 \u00a0 Recent news stories about conflict of interest in biomedical research have shaken up public and private institutions alike, but their focus was on clinical research. Amidst the renewed focus on conflicts of interest in clinical work, let\u2019s not disregard the fact that financial conflicts also pose a concern\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3481,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3481","url_meta":{"origin":2237,"position":5},"title":"Driverless cars: researchers have made a wrong turn","author":"biochemistry","date":"May 9, 2019","format":false,"excerpt":"\u00a0 Academics put at risk a self-driving future by accepting industry\u2019s optimistic predictions and obsessing over irrelevant questions, says Ashley Nunes. \u00a0 Uber Technologies is set to go public this week, an event that has been described as the most anticipated technology filing since Facebook in 2012. 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