{"id":2122,"date":"2018-11-04T12:09:52","date_gmt":"2018-11-04T03:09:52","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=2122"},"modified":"2018-11-04T12:09:52","modified_gmt":"2018-11-04T03:09:52","slug":"rna-%eb%b0%94%ea%bf%94%ec%84%9c-%ed%95%99%ec%97%85%ec%84%b1%ec%a0%81-%eb%86%92%ec%9d%b4%ea%b3%a0-%ea%b8%b0%ec%96%b5%eb%a0%a5-%ed%96%a5%ec%83%81%ec%8b%9c%ed%82%a8%eb%8b%a4%ea%b3%a0","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=2122","title":{"rendered":"RNA \ubc14\uafd4\uc11c \ud559\uc5c5\uc131\uc801 \ub192\uc774\uace0 \uae30\uc5b5\ub825 \ud5a5\uc0c1\uc2dc\ud0a8\ub2e4\uace0?"},"content":{"rendered":"

 <\/p>\n

<\/span><\/p>\n

mRNA<\/span>\u00a0\ubcc0\ud615\uc774 \uae30\uc5b5\uacfc \ud559\uc2b5\ub2a5\ub825 \ud5a5\uc0c1\uc5d0 \ub3c4\uc6c0\uc774 \ub41c\ub2e4\ub294 \uc5f0\uad6c\uacb0\uacfc\uac00 \ub098\uc654\ub2e4.\uc0ac\uc774\uc5b8\uc2a4 \ub370\uc77c\ub9ac<\/em><\/span><\/p>\n

 <\/p>\n

\ub2e8\ubc31\uc9c8\uc740 \uc0dd\uba85\uccb4 \uc791\ub3d9\uc5d0 \uc788\uc5b4\uc11c \ud544\uc218\uc801\uc778 \ub2e8\uc704\uc774\ub2e4.\u00a0\ub2e8\ubc31\uc9c8 \uc0dd\uc0b0\uc744 \uc704\ud574\uc11c\ub294\u00a0DNA<\/span>\uc640\u00a0RNA<\/span>\uc758 \uc720\uae30\uc801 \uc870\uc815\uc774 \ud544\uc694\ud558\ub2e4.\u00a0RNA<\/span>\ub294 \ubb34\uc218\ud55c \uc885\ub958\uc758 \ub2e8\ubc31\uc9c8\uc744 \ub9cc\ub4e4 \ub54c \uc9c1\uc811 \uc791\uc6a9\ud558\ub294 \uace0\ubd84\uc790 \ud654\ud569\ubb3c\uc774\uace0\u00a0DNA<\/span>\ub294\u00a0RNA<\/span>\uc758 \uc791\uc6a9\uc744 \uc870\uc808\ud558\ub294 \uc5ed\ud560\uc744 \ud55c\ub2e4. \uc989\u00a0RNA<\/span>\ub294\u00a0DNA<\/span>\uac00 \uac16\uace0 \uc788\ub294 \uc720\uc804\uc815\ubcf4\uc5d0 \ub530\ub77c \ud544\uc694\ud55c \ub2e8\ubc31\uc9c8\uc744 \ud569\uc131\ud558\ub294 \uc5ed\ud560\uc744 \ud558\ub294 \ubb3c\uc9c8\uc774\ub2e4.<\/p>\n

\ucd5c\uadfc \uc911\uad6d\uacfc \ubbf8\uad6d \uc5f0\uad6c\uc790\ub4e4\uc774\u00a0RNA<\/span>\uc758 \ubcc0\ud654\uac00 \uae30\uc5b5\uacfc \ud559\uc2b5\uc5d0 \uc9c1\uc811\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud588\ub2e4.<\/p>\n

\ubbf8\uad6d \uc2dc\uce74\uace0\ub300 \ud654\ud559\uacfc, \uc0dd\ud654\ud559\u00b7\ubd84\uc790\uc0dd\ubb3c\ud559\uacfc, \uc2e0\uacbd\uc0dd\ubb3c\ud559\uacfc, \uc0dd\ubb3c\ubb3c\ub9ac\uc5ed\ud559\uc5f0\uad6c\uc18c, \ud558\uc6cc\ub4dc\ud734\uc988\uc758\ud559\uc5f0\uad6c\uc18c, \ud39c\uc2e4\ubca0\ub2c8\uc544\ub300 \uc758\ub300, \uc911\uad6d \uc0c1\ud558\uc774\uacf5\ub300 \uc0dd\uba85\uacfc\ud559\uacf5\ud559\ubd80, \uc800\uc7a5\ub300 \uc2e4\ud5d8\ub3d9\ubb3c\uc13c\ud130, \ud654\ub465\uc0ac\ubc94\ub300 \uc0dd\uba85\uacfc\ud559\ubd80, \ub09c\uc9d5\uc758\ub300 \uacf5\ub3d9\uc5f0\uad6c\ud300\uc740\u00a0mRNA<\/span>(\uba54\uc2e0\uc800RNA<\/span>)\uc758 \ud654\ud559\uc801 \ubcc0\ud615 \ud615\ud0dc\uc778 N6-\uba54\ud2f8\uc544\ub370\ub178\uc2e0(m6A)\uc744 \uc778\uc2dd\ud558\ub294 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\uc774 \ud559\uc2b5\uacfc \uae30\uc5b5 \ud615\uc131 \uacfc\uc815\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ud655\uc778\ud588\ub2e4\uace0 2\uc77c \ubc1d\ud614\ub2e4. \uc774\ubc88 \uc5f0\uad6c\uacb0\uacfc\ub294 \uc138\uacc4\uc801\uc778 \uacfc\ud559\uc800\ub110 \u2018\ub124\uc774\ucc98\u2019 \uc9c0\ub09c\ub2ec 31\uc77c\uc790\uc5d0 \uc2e4\ub838\ub2e4.<\/p>\n

\ud6c4\uc131\uc720\uc804\ud559(epigenetics<\/span>)\uc740\u00a0DNA<\/span>\ub098\u00a0RNA<\/span>\uc758 \uc5fc\uae30\uc11c\uc5f4\uc774 \ubcc0\ud654\ud558\uc9c0 \uc54a\ub294 \uc0c1\ud0dc\uc5d0\uc11c \uc678\ubd80 \ub610\ub294 \ud658\uacbd\uc801 \uc694\uc778\uc73c\ub85c \uc778\ud574 \ud654\ud559\uc801 \ubcc0\ud615\ub9cc\uc73c\ub85c\ub3c4 \uc720\uc804\uc790 \ubc1c\ud604 \uc0c1\ud0dc\uac00 \ub2ec\ub77c\uc9c0\ub294 \uac83\uc744 \uc5f0\uad6c\ud558\ub294 \ud559\ubb38\uc774\ub2e4. \ubd84\uc790\uc801 \uc218\uc900\uc5d0\uc11c \uc815\ud655\ud788 \uc774\ud574\ub418\uace0 \uc788\uc9c0\ub294 \uc54a\uc9c0\ub9cc\u00a0DNA<\/span>\u00a0\uba54\ud2f8\ud654\uc640 \ud788\uc2a4\ud1a4 \ub2e8\ubc31\uc9c8\uc758 \ubcc0\ud615\uc774 \uc6d0\uc778\uc73c\ub85c \uc54c\ub824\uc838 \uc788\ub2e4. \uc2e4\uc81c\ub85c \ud6c4\uc131\uc720\uc804\ud559\uc801 \ubcc0\ud654\ub294 \uba74\uc5ed\uacc4 \ubc18\uc751, \uc2e0\uacbd\uacc4 \ubc1c\ub2ec, \uc554, \ube44\ub9cc \ub4f1 \ub2e4\uc591\ud55c \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc73c\ub85c \uc774\ud574\ub418\uace0 \uc788\ub2e4.<\/p>\n

DNA<\/span>\uc5d0\uc11c \ub2e8\ubc31\uc9c8\ub85c \uc815\ubcf4\ub97c \uc804\ub2ec\ud558\ub294 \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \uba54\uc2e0\uc800RNA<\/span>(mRNA<\/span>)\uc774\ub2e4. \ud3ec\uc720\ub958\uc758\u00a0mRNA<\/span>\uc5d0 \uc788\uc5b4\uc11c \uac00\uc7a5 \uc77c\ubc18\uc801\uc778 \ubcc0\ud615\uc740 m6A\uc73c\ub85c \uc2e0\uacbd\uacc4\uc5d0 \ub110\ub9ac \ud37c\uc838 \uc788\uc73c\uba74\uc11c \uc2e0\uacbd\uae30\ub2a5 \uc77c\ubd80\ub97c \uc870\uc815\ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\ub2e4.<\/p>\n

\uc5f0\uad6c\ud300\uc740 m6A\ub97c \uc778\uc2dd\ud558\ub294 \u2018Ythdf<\/span>1\u2019\uc774\ub77c\ub294 \ub2e8\ubc31\uc9c8\uc774 \ud559\uc2b5\uacfc \uae30\uc5b5 \ud615\uc131 \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud55c \uac83\uc774\ub2e4. \uc5f0\uad6c\ud300\uc740 3\uc138\ub300 \uc720\uc804\uc790 \uac00\uc704\uae30\uc220\uc778 \ud06c\ub9ac\uc2a4\ud37c-\uce90\uc2a49\uc744 \uc774\uc6a9\ud574 \uc0dd\uc950\uc5d0\uac8c\uc11c\u00a0Ythdf<\/span>1 \ub2e8\ubc31\uc9c8\uc744 \uc81c\uac70\ud55c \ub4a4 \ud559\uc2b5\uacfc \uae30\uc5b5 \uc2e4\ud5d8\uc744 \ud588\ub2e4.<\/p>\n

\uc5f0\uad6c\ud300\uc740\u00a0Ythdf<\/span>1 \ub2e8\ubc31\uc9c8\uc774 \uc644\uc804\ud788 \uc81c\uac70\ub41c \uc0dd\uc950\uc640 \uc77c\ubc18 \uc0dd\uc950\ub97c \ub300\uc0c1\uc73c\ub85c \ubbf8\ub85c \ucc3e\uae30\uc640 \uc218\uc601 \uce21\uc815, \ud2b9\uc815 \uc18c\ub9ac\uc640 \ud568\uaed8 \uc804\uae30\ucda9\uaca9\uc744 \uac00\ud55c \ub4a4 \uccad\uac01 \uacf5\ud3ec\uae30\uc5b5\uc744 \uce21\uc815\ud588\ub2e4. \uadf8 \uacb0\uacfc\u00a0Ythdf<\/span>1 \ub2e8\ubc31\uc9c8\uc774 \uc81c\uac70\ub41c \uc0dd\uc950\ub294 \ubbf8\ub85c\ucc3e\uae30\ub294 \ubb3c\ub860 \uccad\uac01\uacf5\ud3ec \uccb4\ud5d8\uc744 \uc5ec\ub7ec \ubc88 \ubc18\ubcf5\uc2dc\ucf1c\ub3c4 \uae30\uc5b5\uc744 \ud558\uc9c0 \ubabb\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \uc5f0\uad6c\ud300\uc740 \uc774 \uc0dd\uc950\uc5d0\uac8c\u00a0Ythdf<\/span>1 \ub2e8\ubc31\uc9c8\uc744 \uc8fc\uc785\ud574 \ub2e4\uc2dc \ub611\uac19\uc740 \uc2e4\ud5d8\uc744 \ud55c \uacb0\uacfc \uae30\uc5b5\ub825\uacfc \ud559\uc2b5 \uacfc\uc81c \uc218\ud589 \ub2a5\ub825\uc774 \ud5a5\uc0c1\ub418\ub294 \uac83\uc744 \ud655\uc778\ud588\ub2e4.\u00a0RNA<\/span>\u00a0\ubcc0\ud615 \ub2e8\ubc31\uc9c8\uc774 \uae30\uc5b5\uacfc \ud559\uc2b5\ub2a5\ub825 \ud5a5\uc0c1\uc5d0 \ub3c4\uc6c0\uc744 \uc900\ub2e4\ub294 \uc124\uba85\uc774\ub2e4.<\/p>\n

\uc1a1\ud64d\uc900 \ud39c\uc2e4\ubca0\ub2c8\uc544\ub300 \uc758\ub300 \uc2e0\uacbd\uacfc\ud559\uacfc \uad50\uc218\ub294 \uc774\ubc88 \uc5f0\uad6c\ub294 \uc720\uc804\uc790 \ubc88\uc5ed \uacfc\uc815\uc774 \ubcc0\ud654\ub420 \uacbd\uc6b0 \uc2e0\uacbd\uc790\uadf9\uc774 \uc5b4\ub5bb\uac8c \ubc18\uc751\ud558\ub294\uc9c0\ub97c \ubcf4\uc5ec\uc8fc\ub294 \ud765\ubbf8\ub85c\uc6b4 \ubc1c\uacac\u201d\uc774\ub77c\uba70 \u201cm6A \ubcc0\ud615\uc740 \ud559\uc2b5\uacfc \uae30\uc5b5 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uba74\uc5ed\uacc4\uc5d0\uc11c\ub3c4 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\ub294 \ub9cc\ud07c \ub2e4\ub978 \uc790\uadf9\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uae4c\uc9c0 \ucd94\uac00\uc801 \uc5f0\uad6c\uac00 \ud544\uc694\ud558\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

 <\/p>\n

 <\/p>\n

\uc6d0\ubb38: \uc5ec\uae30<\/a>\ub97c \ud074\ub9ad\ud558\uc138\uc694~<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

  mRNA\u00a0\ubcc0\ud615\uc774 \uae30\uc5b5\uacfc \ud559\uc2b5\ub2a5\ub825 \ud5a5\uc0c1\uc5d0 \ub3c4\uc6c0\uc774 \ub41c\ub2e4\ub294 \uc5f0\uad6c\uacb0\uacfc\uac00 \ub098\uc654\ub2e4.\uc0ac\uc774\uc5b8\uc2a4 \ub370\uc77c\ub9ac   \ub2e8\ubc31\uc9c8\uc740 \uc0dd\uba85\uccb4 \uc791\ub3d9\uc5d0 \uc788\uc5b4\uc11c \ud544\uc218\uc801\uc778 \ub2e8\uc704\uc774\ub2e4.\u00a0\ub2e8\ubc31\uc9c8 \uc0dd\uc0b0\uc744 \uc704\ud574\uc11c\ub294\u00a0DNA\uc640\u00a0RNA\uc758 \uc720\uae30\uc801 \uc870\uc815\uc774 \ud544\uc694\ud558\ub2e4.\u00a0RNA\ub294 \ubb34\uc218\ud55c \uc885\ub958\uc758 \ub2e8\ubc31\uc9c8\uc744(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[33,29,30],"tags":[],"class_list":["post-2122","post","type-post","status-publish","format-standard","hentry","category-do-biology","category-lets-do-science","category-recent-science-news"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":1876,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1876","url_meta":{"origin":2122,"position":0},"title":"\uaf2c\ub9ac\uac00 \uae38\uba74 \ubc1f\ud788\ub294 \ubc95, mRNA\uc758 \uaf2c\ub9ac\ub97c \ucc3e\uc544\uc11c","author":"biochemistry","date":"September 26, 2018","format":false,"excerpt":"\u00a0 \u00a0 mRNA \uaf2c\ub9ac\uc5d0 \uad00\ud55c \uc11c\uc6b8\ub300 \uae40\ube5b\ub0b4\ub9ac \uad50\uc218\ub2d8\uc758 \ucd5c\uadfc \ub17c\ubb38 \uc124\uba85\uc785\ub2c8\ub2e4~ (\uc6d0\ubb38) \u00a0 \ub2e8\ubc31\uc9c8\uacfc \uc138\ud3ec\uc758 \uc6b4\uba85 \uacb0\uc815\uc790, \uc804\ub839RNA(mRNA) \uace0\ud608\uc555 \ud658\uc790\uc640 \ub9c8\ub77c\ud1a4 \uc120\uc218\uc758 \uacf5\ud1b5\uc810\uc774 \uc788\ub2e4.\u00a0\uc2ec\uc7a5\uc774 \uc77c\ubc18 \uc0ac\ub78c\ubcf4\ub2e4 \ud06c\ub2e4\ub294 \uac83.\u00a0\ub450 \uc0ac\ub78c \ubaa8\ub450 \ucee4\ub2e4\ub780 \uc2ec\uc7a5\uc744 \uac00\uc84c\ub2e4\ub294 \uc870\uac74\uc740 \uac19\ub2e4.\u00a0\ud558\uc9c0\ub9cc \uac74\uac15 \uce21\uba74\uc5d0\uc11c \uacb0\uacfc\ub294 \ub2e4\ub974\ub2e4.\u00a0\uace0\ud608\uc555 \ud658\uc790\ub294 \uc2ec\uc7a5\ub9c8\ube44\ub97c \uc553\uc744 \uac00\ub2a5\uc131\uc774 \ud06c\uc9c0\ub9cc \ub9c8\ub77c\ud1a4 \uc120\uc218\ub294 \ub300\uccb4\uc801\uc73c\ub85c \uac74\uac15\ud55c \uc0b6\uc744 \uc0b0\ub2e4.\u00a0\uc774\uc720\uac00\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/163.180.4.222\/lab\/wp-content\/uploads\/2018\/09\/200211140272_01-300x210.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1683,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1683","url_meta":{"origin":2122,"position":1},"title":"\uc791\uc740 RNA \uc870\uac01, \uc720\uc804\uc790 \uc9c8\ud658 \uadf9\ubcf5\uc758 \uc5f4\uc1e0 \ub420\uae4c & RNA \uc804\uc0ac\uccb4\uac00 \uc88c\uc6b0\ud558\ub294 \uc138\ud3ec\uc758 \uc6b4\uba85","author":"biochemistry","date":"September 12, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) \u00a0 \u00a0 RNA \uac04\uc12d\uc774 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud55c\ub2e4? \u00a0 \uc0dd\uba85\uc5d0 \uad00\ud55c \uc720\uc804\uc815\ubcf4\ub97c \ub2f4\uace0 \uc788\ub294\u00a0DNA\ub294\u00a0\ub450 \uac00\ub2e5\uc758 \uc774\uc911\ub098\uc120 \uad6c\uc870\ub97c \uc774\ub8e8\uace0 \uc788\ub2e4. DNA\uc758 \uc720\uc804\uc815\ubcf4\ub97c \ub530\ub77c\u00a0RNA\uac00 \ub9cc\ub4e4\uc5b4\uc9c0\uace0,\u00a0RNA\ub294 \uc6d0\ubcf8\u00a0DNA\uac00 \uac00\uc9c4 \uc815\ubcf4\ub97c \ubcf5\uc0ac\ud574 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uace0 \ub2e8\ubc31\uc9c8 \ud569\uc131\uc5d0 \uc911\ucd94\uc801 \uc5ed\ud560\uc744 \uc218\ud589\ud55c\ub2e4.\u00a0\uacfc\uac70\u00a0RNA\ub294\u00a0DNA\ub97c \uad6c\uc131\ud558\ub294 \uc218\ub3d9\uc801\uc778 \uc874\uc7ac\ub85c \uc5ec\uaca8\uc84c\uc73c\ub098 \uc810\ucc28 \uadf8 \uc911\uc694\uc131\uc774 \ud06c\uac8c \ub300\ub450\ub418\uace0 \uc788\ub2e4. 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