{"id":1559,"date":"2018-09-05T17:43:32","date_gmt":"2018-09-05T08:43:32","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=1559"},"modified":"2019-10-14T14:57:05","modified_gmt":"2019-10-14T05:57:05","slug":"university-clears-ngago-gene-editing-study-authors-of-deception","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1559","title":{"rendered":"University clears NgAgo gene-editing study authors of deception & ‘\uc911\uad6d\ud310 \ud669\uc6b0\uc11d \uc0ac\ud0dc’ \ub17c\ub780 “\uc870\uc791 \uc758\ub3c4 \uc5c6\ub2e4” \uacb0\ub860"},"content":{"rendered":"

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(\uc6d0\ubb38<\/a>)<\/p>\n

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But an investigation confirmed that the study was flawed.<\/h6>\n

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A Chinese university has concluded that the authors of a controversial gene-editing paper that was later retracted did not intend to deceive the scientific community. The\u00a0paper<\/a>, published in\u00a0Nature Biotechnology<\/i>on 2 May 2016, detailed how an enzyme called NgAgo could edit genomes with similar accuracy and efficiency to the widely used CRISPR\u2013Cas9 gene-editing system.<\/p>\n

As a result of the paper, lead author Han Chunyu, a molecular biologist at Hebei University of Science and Technology in Shijiazhuang, became a research star in China. He was made vice-president of the Hebei Association of Science and Technology, and plans were afoot for the university to build a 224-million-yuan (US$33-million) research centre, which Han would lead.<\/p>\n

But the paper\u2019s main finding was within months challenged by scientists who failed to reproduce the results. On 2 August last year, Han and his co-authors agreed to retract the paper, citing other researchers\u2019 inability to replicate the results. (Nature<\/i>\u2019s news team is editorially independent of\u00a0Nature Biotechnology<\/i>.)<\/p>\n

Last week, Han\u2019s university announced that it had concluded its investigation into the experiments by Han\u2019s team. As part of the investigation, the university used an independent laboratory to reproduce the experiments, but they failed to replicate the main findings. The investigation concluded that there was no basis for believing that the original experiment should be republished. But the university found no evidence of intentional deceit by the group.<\/p>\n

A statement posted on the university website on 1 September says that Han has accepted the conclusions of the university\u2019s investigation, admitted that there were flaws in the experimental design, and apologized for misleading other scientists in a way that resulted in them wasting resources in trying to reproduce the study. The statement also says that Han apologized for \u201cfailing to remain calm in the face of doubts from his peers and the media\u201d. Han will continue in his position at the university. He could not be reached for comment.<\/p>\n

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http:\/\/dongascience.donga.com\/news\/view\/23802<\/p>\n

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‘\uc911\uad6d\ud310 \ud669\uc6b0\uc11d \uc0ac\ud0dc’ \ub17c\ub780 “\uc870\uc791 \uc758\ub3c4 \uc5c6\ub2e4” \uacb0\ub860<\/h5>\n

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\ud5c8\ubca0\uc774\uacfc\uae30\ub300, \ub17c\ub780 2\ub144 \ub9cc\uc5d0 \uacf5\uc2dd \uc785\uc7a5 \ubc1c\ud45c<\/strong><\/p>\n

<\/span><\/p>\n

\ub17c\ubb38 \uc870\uc791 \ub17c\ub780\uc73c\ub85c \u2018\uc911\uad6d\ud310 \ud669\uc6b0\uc11d \uc0ac\ud0dc\u2019\ub97c \ube5a\uc740 \ud55c\ucd98\uc704 \uc911\uad6d \ud5c8\ubca0\uc774\uacfc\ud559\uae30\uc220\ub300 \uad50\uc218. \ud5c8\ubca0\uc774\uacfc\uae30\ub300<\/em><\/span><\/p>\n

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\uc0c8\ub85c\uc6b4 \uc720\uc804\uccb4(\uac8c\ub188) \uad50\uc815 \uae30\uc220\uc744 \uac1c\ubc1c\ud574 \uc138\uac04\uc758 \uc8fc\ubaa9\uc744 \ubc1b\uc558\ub2e4\uac00 \ub17c\ubb38\uc774 \ucca0\ud68c\ub418\ub294 \ub4f1 \uc9c4\uc704 \ub17c\ub780\uc73c\ub85c \u2018\uc911\uad6d\ud310 \ud669\uc6b0\uc11d \uc0ac\ud0dc\u2019\ub97c \ube5a\uc740 \ud55c\ucd98\uc704(\u97d3\u6625\u96e8\u00b744) \uc911\uad6d \ud5c8\ubca0\uc774\uacfc\ud559\uae30\uc220\ub300 \uc0dd\uba85\uacf5\ud559\uacfc \ubd80\uad50\uc218\uc5d0 \ub300\ud574 \ub300\ud559 \uce21 \uc870\uc0ac\uc704\uc6d0\ud68c\uac00 \u201c\uc758\ub3c4\uc801\uc778 \uc870\uc791\uc740 \uc544\ub2c8\uc5c8\ub2e4\u201d\ub294 \ucd5c\uc885 \uacb0\ub860\uc744 \ub0b4\ub838\ub2e4.<\/p>\n

\uc9c0\ub09c\ub2ec 31\uc77c(\ud604\uc9c0 \uc2dc\uac04) \ud5c8\ubca0\uc774\uacfc\uae30\ub300\ub294 \uacf5\uc2dd \ud648\ud398\uc774\uc9c0\ub97c \ud1b5\ud574 \ud55c \uad50\uc218\ub97c \ub458\ub7ec\uc2fc \ub17c\ub780\uc5d0 \ub300\ud55c \uc870\uc0ac \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\ub2e4. \uacf5\uc2dd \uc785\uc7a5\ubb38\uc5d0\uc11c \ud5c8\ubca0\uc774\uacfc\uae30\ub300 \uce21\uc740 \u201c\ud55c\ucd98\uc704 \uad50\uc218\uac00 2016\ub144 \ubc1c\ud45c\ud55c \ub17c\ubb38\uc744 \ud1a0\ub300\ub85c \uc81c3\uc790\uc758 \ub3c5\ub9bd\uc801\uc778 \uc5f0\uad6c\uc9c4\uc744 \ud1b5\ud574 \uc2e4\ud5d8\uc744 \ud588\uc9c0\ub9cc, \ub17c\ubb38\uacfc \ub3d9\uc77c\ud55c \uacb0\uacfc\ub97c \uc5bb\uc9c0 \ubabb\ud588\ub2e4\u201d\uba74\uc11c\ub3c4 \u201c\ub2e4\ub9cc \uc758\ub3c4\uc801\uc778 \uc870\uc791 \ud754\uc801\uc740 \ubc1c\uacac\ud558\uc9c0 \ubabb\ud588\uace0 \uadf8\uac00 \ud559\uad50\uc5d0 \ub0a8\uc544 \uc5f0\uad6c\ub97c \uacc4\uc18d \uc774\uc5b4\ub098\uac08 \uac83\u201d\uc774\ub77c\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\uc720\uc804\uccb4 \uad50\uc815 \uae30\uc220\uc740\u00a0DNA<\/span>\uc5d0\uc11c \uc6d0\ud558\ub294 \uc720\uc804\uc790\ub9cc \uc120\ud0dd\uc801\uc73c\ub85c \uc798\ub77c\ub0b4\uac70\ub098 \ubc14\uafd4 \uc8fc\ub294 \uae30\uc220\uc774\ub2e4. 2012\ub144 \uc815\ud655\ub3c4\uc640 \ud6a8\uc728\uc774 \ud68d\uae30\uc801\uc73c\ub85c \uac1c\uc120\ub41c \u2018\ud06c\ub9ac\uc2a4\ud37c(CRISPR<\/span>–Cas<\/span>9) \uc720\uc804\uc790 \uac00\uc704\u2019\uac00 \ub4f1\uc7a5\ud558\uba74\uc11c \ub208\ubd80\uc2e0 \ubc1c\uc804\uc744 \uac70\ub4ed\ud588\ub2e4. \ub09c\uce58\uc131 \uc720\uc804\uc9c8\ud658\uc744 \uadfc\ubcf8\uc801\uc73c\ub85c \uce58\ub8cc\ud558\uac70\ub098 \uae30\ud6c4\ubcc0\ud654\uc5d0 \uac15\ud55c \ub18d\uc791\ubb3c\uc744 \uac1c\ubc1c\ud558\ub294 \ub4f1 \ub2e4\uc591\ud55c \ubd84\uc57c\uc5d0 \uc751\uc6a9\ud560 \uc218 \uc788\ub2e4.<\/p>\n

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\ud5c8\ubca0\uc774\uacfc\ud559\uae30\uc220\ub300\uac00 \uc5f0\uad6c \uacb0\uacfc \uc9c4\uc704 \ub17c\ub780\uc5d0 \ud729\uc2f8\uc778 \ud55c\ucd98\uc704 \uad50\uc218\uc5d0 \ub300\ud55c \ub300\ud559 \uce21 \uc870\uc0ac\uc704\uc6d0\ud68c\uc758 \uc870\uc0ac \uacb0\uacfc\ub97c \uacf5\uc2dd \ud648\ud398\uc774\uc9c0\ub97c \ud1b5\ud574 \uacf5\uac1c\ud588\ub2e4. – \ud5c8\ubca0\uc774\uacfc\uae30\ub300 \ud648\ud398\uc774\uc9c0<\/em><\/span><\/p>\n

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\u25cb \u2018\ud06c\ub9ac\uc2a4\ud37c\u2019 \ub6f0\uc5b4\ub118\ub294 \uc720\uc804\uc790 \uac00\uc704?\u2026\uacfc\ud559\uacc4\u00a0<\/strong>\u201c\uc2e4\ud5d8\uacb0\uacfc \uc7ac\ud604 \ubd88\uac00\ub2a5<\/strong>\u201d<\/strong><\/p>\n

\uc774\ub7f0 \uac00\uc6b4\ub370 \ud55c\ucd98\uc704 \uad50\uc218\uac00 2016\ub144 5\uc6d4 \u2018\uc5d4\uc950\uc544\uace0(NgAgo<\/span>)\u2019\ub85c \ubd88\ub9ac\ub294 \uc720\uc804\uc790 \uc808\ub2e8\ud6a8\uc18c\ub85c \ud06c\ub9ac\uc2a4\ud37c \uc720\uc804\uc790 \uac00\uc704\ub97c \ub2a5\uac00\ud558\ub294 \uc0c8\ub85c\uc6b4 \uc720\uc804\uccb4 \uad50\uc815 \uae30\uc220(NgAgo<\/span>–gDNA<\/span>)\uc744 \uac1c\ubc1c\ud588\ub2e4\uace0 \uc0dd\uba85\uacf5\ud559 \ubd84\uc57c \ucd5c\uace0 \uad8c\uc704\uc758 \uad6d\uc81c\ud559\uc220\uc9c0 \u2018\ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0\u2019\uc5d0 \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\ub2e4. \ud06c\ub9ac\uc2a4\ud37c\ub294\u00a0RNA<\/span>\u00a0\ub2e8\ubc31\uc9c8\uc744 \ud1b5\ud574\u00a0Cas<\/span>9 \uc808\ub2e8\ud6a8\uc18c\uac00\u00a0DNA<\/span>\u00a0\ud45c\uc801 \ubd80\uc704\uc5d0 \ub2ec\ub77c \ubd99\ub294 \ubc29\uc2dd\uc774\uc9c0\ub9cc,\u00a0NgAgo<\/span>–gDNA<\/span>\ub294\u00a0DNA<\/span>\uac00\u00a0NgAgo<\/span>\u00a0\uc808\ub2e8\ud6a8\uc18c\ub97c \ud45c\uc801 \ubd80\uc704\ub85c \uc774\ub048\ub2e4\ub294 \uac83\uc774\ub2e4. \ud55c \uad50\uc218\ud300\uc740\u00a0NgAgo<\/span>–gDNA<\/span>\ub85c \uc0b4\uc544 \uc788\ub294 \uc778\uccb4 \uc138\ud3ec\uc758 \uc720\uc804\uccb4\ub97c \ud3b8\uc9d1\ud558\ub294 \ub370 \uc131\uacf5\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

\uc774 \ub17c\ubb38 \ud55c \ud3b8\uc73c\ub85c \uadf8\ub294 \uc911\uad6d\uc758 \uc80a\uc740 \uc2a4\ud0c0 \uacfc\ud559\uc790\ub85c \ub5a0\uc62c\ub790\ub2e4. \u2018\uc591\ucbd4\uac15 \ud559\uc790\uc0c1\u2019 \u2018\uad6d\uac00 \uc2e0\uc9c4\u00b7\uc911\uacac \uae30\uc220\ud601\uc2e0\ub9ac\ub354\uc0c1\u2019 \ub4f1 \uc911\uad6d \ucd5c\uace0 \uad8c\uc704\uc758 \ud559\uc220\uc0c1\uc744 \ud729\uc4f8\uc5c8\uace0, \uc5b8\ub860\uc5d0\uc120 \uc911\uad6d \ud1a0\uc885 \uacfc\ud559\uc790\uc778 \uadf8\ub97c \u2018\ucc28\uae30 \ub178\ubca8\uc0c1 \ud6c4\ubcf4\u2019\ub85c \ub300\uc11c\ud2b9\ud544\ud588\ub2e4. \ub2f9\uc2dc \uc911\uad6d \uc815\ubd80\ub294 \ud55c \uad50\uc218\uac00 \uc774\ub04c \uc720\uc804\uccb4\uad50\uc815\uae30\uc220\uc5f0\uad6c\uc13c\ud130\ub97c \uad6c\ucd95\ud558\uae30 \uc704\ud574 2\uc5b52400\ub9cc \uc704\uc548(\uc57d 363\uc5b56000\ub9cc \uc6d0) \uaddc\ubaa8\uc758 \uc608\uc0b0\uc744 \uc2b9\uc778\ud588\ub2e4. \uae00\ub85c\ubc8c \uc0dd\uba85\uacf5\ud559\uae30\uc5c5\uc778 \ub374\ub9c8\ud06c\uc758 \ub178\ubcf4\uc790\uc784\uc740 \ud55c \uad50\uc218\ub85c\ubd80\ud130\u00a0NgAgo<\/span>\u00a0\ud6a8\uc18c\uc758 \ud2b9\ud5c8\uc2e4\uc2dc\uad8c\uc744 \ud655\ubcf4\ud588\ub2e4\uace0 \ubc1c\ud45c\ud558\uae30\ub3c4 \ud588\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \ub17c\ubb38 \ubc1c\ud45c \ud6c4 \ud55c \ub2ec \uc5ec \ub4a4\ubd80\ud130 \ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0 \uce21\uc5d0 \ud55c \uad50\uc218\uc758 \uc5f0\uad6c \uacb0\uacfc\ub294 \uc7ac\ud604(\u518d\u73fe)\uc774 \ubd88\uac00\ub2a5 \ud558\ub2e4\ub294 \uc138\uacc4 \uac01\uad6d \uacfc\ud559\uc790\ub4e4\uc758 \ud56d\uc758\uac00 \ube57\ubc1c\ucce4\ub2e4. \ud55c \uad50\uc218\uc5d0\uac8c\ub294 \ub17c\ubb38\uc5d0 \uc0ac\uc6a9\ud55c \uae30\ucd08 \ub370\uc774\ud130 \uc6d0\ubcf8\uc744 \uacf5\uac1c\ud558\ub77c\ub294 \uc694\uad6c\uac00 \uc774\uc5b4\uc84c\uace0, \ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0\ub3c4 \uc9c4\uc0c1 \ud30c\uc545\uc5d0 \ub098\uc11c\uaca0\ub2e4\uace0 \uacf5\uc2dd \ubc1c\ud45c\ud588\ub2e4. \uc774\ub97c \ub450\uace0 \uad6d\ub0b4\uc678 \uc5b8\ub860\uc740 \ub17c\ubb38 \uc870\uc791\uc73c\ub85c \uc804 \uc138\uacc4\ub97c \ub5a0\ub4e4\uc369\ud558\uac8c \ub9cc\ub4e4\uc5c8\ub358 \ud55c\uad6d\uc758 \u2018\ud669\uc6b0\uc11d \uc0ac\ud0dc\u2019\uc640 \uc77c\ubcf8\uc758 \u2018\uc624\ubcf4\uce74\ud0c0 \uc0ac\uac74\u2019\uc5d0 \ube57\ub300\uba70 \ud55c \uad50\uc218\uc758 \ub17c\ubb38 \uc870\uc791 \uac00\ub2a5\uc131\uc744 \uc81c\uae30\ud588\ub2e4.<\/p>\n

\ud55c \uad50\uc218\ub294 \uc774 \uac19\uc740 \uc758\ud639\uc5d0 \uacb0\ubc31\uc744 \uc8fc\uc7a5\ud588\ub2e4. \ub2f9\uc2dc \uadf8\ub294 \uc911\uad6d\uc5d0\uc11c \uc5f4\ub9b0 \uae30\uc790\ud68c\uacac\uc5d0\uc11c \u201c\uc6b0\ub9ac \uc5f0\uad6c\uc2e4\uc5d0\uc11c\ub294 \ub17c\ubb38 \ubc1c\ud45c \uc774\ud6c4\uc5d0\ub3c4 \uc218\ucc28\ub840 \uc7ac\ud604\uc5d0 \uc131\uacf5\ud588\ub2e4. \uc7ac\ud604\uc744 \ud558\uc9c0 \ubabb\ud55c \uac83\uc740 \uc138\ud3ec\uac00 \uc624\uc5fc\ub410\uac70\ub098 \ubd80\uc815\ud655\ud55c \ubc29\ubc95\uc744 \uc0ac\uc6a9\ud588\uae30 \ub54c\ubb38\u201d\uc774\ub77c\uace0 \uc9c0\uc801\ud558\uae30\ub3c4 \ud588\ub2e4.<\/p>\n

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\uc808\ub2e8\ud6a8\uc18c \u2018\uc5d4\uc950\uc544\uace0(NgAgo<\/span>)\u2019\uac00 \ub2f4\uae34 \ub2e8\ubc31\uc9c8. – \ub124\uc774\ucc98<\/em><\/span><\/p>\n

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\u25cb \uc9c4\uc0c1\uc870\uc0ac \ub05d\uc5d0 \ub17c\ubb38 \ucca0\ud68c, \ub300\ud559 \uce21 \uc870\uc0ac\uc704\ub3c4 \ub4a4\ub2a6\uac8c \uc778\uc815<\/strong><\/p>\n

2016\ub144 8\uc6d4 \ud55c \uad50\uc218\uac00 \ub17c\ubb38\uc758 \uae30\ucd08 \ub370\uc774\ud130\uae4c\uc9c0 \uacf5\uac1c\ud588\uc9c0\ub9cc \uc0c1\ud669\uc740 \ub2ec\ub77c\uc9c0\uc9c0 \uc54a\uc558\ub2e4. \uc624\ud788\ub824 \ud55c \uad50\uc218\uc758 \ub17c\ubb38 \ub0b4\uc6a9\uc774 \uc0ac\uc2e4\uacfc \ub2e4\ub974\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \ub3d9\ub8cc\ud3c9\uac00(peer<\/span>–review<\/span>\u00b7\ud53c\uc5b4\ub9ac\ubdf0) \ub17c\ubb38\uc73c\ub85c \ubc1c\ud45c\ub418\uae30 \uc2dc\uc791\ud558\uba74\uc11c \uadf8\uc5d0 \ub300\ud55c \uacfc\ud559\uacc4\uc758 \ud3c9\uac00\ub294 \ud655\uc2e4\uc2dc \ub410\ub2e4.<\/p>\n

\ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0 \uce21\ub3c4 \uad00\ub828 \ub17c\ubb38\uc744 \ubc1b\uc544\ub4e4\uc600\ub2e4. \uae40\uc9c4\uc218 \uae30\ucd08\uacfc\ud559\uc5f0\uad6c\uc6d0(IBS<\/span>) \uc720\uc804\uccb4\uad50\uc815\uc5f0\uad6c\ub2e8\uc7a5 \uc5f0\uad6c\ud300\uc740 \ubbf8\uad6d \uba54\uc774\uc694\ud074\ub9ac\ub2c9, \ub3c5\uc77c \ud504\ub77c\uc774\ubd80\ub974\ud06c\ub300\uc640 \ud568\uaed8\u00a0NgAgo<\/span>–gDNA<\/span>\ub85c\ub294 \uc720\uc804\uccb4 \uad50\uc815\uc774 \ub418\uc9c0 \uc54a\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4\uace0 2016\ub144 11\uc6d4 \ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0\uc5d0 \ubc1c\ud45c\ud588\ub2e4. \uae40 \ub2e8\uc7a5\uc740 \u201cNgAgo<\/span>\u00a0\uc808\ub2e8\ud6a8\uc18c\ub294 \uc720\uc804\uc815\ubcf4\ub97c \ub2f4\uace0 \uc788\ub294\u00a0DNA<\/span>\uac00 \uc544\ub2cc\u00a0RNA<\/span>\ub97c \uc790\ub974\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4\u201c\uba70 \u201c\uc2e4\ud5d8 \uacb0\uacfc\ub97c \uc798\ubabb \ud574\uc11d\ud588\uac70\ub098\u00a0RNA<\/span>\uc5d0\uc11c \uc5bb\uc740 \ub370\uc774\ud130\ub97c \ubc14\ud0d5\uc73c\ub85c\u00a0DNA<\/span>\ub97c \uad50\uc815\ud55c \uac83\ucc98\ub7fc \uc77c\ubd80\ub7ec \uc870\uc791\ud588\uc744 \uac00\ub2a5\uc131\uc774 \ub192\ub2e4\u201c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\uacb0\uad6d \uc9c0\ub09c\ud574 8\uc6d4 \ud55c \uad50\uc218\uc758 \ub17c\ubb38\uc740 \ucca0\ud68c\ub410\ub2e4. \ud5c8\ubca0\uc774\uacfc\uae30\ub300\ub294 \ub17c\ubb38\uc774 \ucca0\ud68c\ub418\uace0 \ub09c \ub4a4\uc5d0\uc57c \ub4a4\ub2a6\uac8c \uc870\uc0ac\uc704\ub97c \uafb8\ub824 \uc9c4\uc0c1 \uc870\uc0ac\uc5d0 \ucc29\uc218\ud588\ub2e4. \uadf8 \uc0ac\uc774 \uc720\uc804\uccb4\uad50\uc815\uae30\uc220\uc5f0\uad6c\uc13c\ud130 \uac74\ub9bd\uc740 \ubb3c\ub860\uc774\uace0 \ud55c \uad50\uc218 \uc55e\uc73c\ub85c \uc218\uc5ec\ub41c \uac01\uc885 \uc0c1\ub4e4\ub3c4 \uc904\uc904\uc774 \ucde8\uc18c\ub410\ub2e4.<\/p>\n

\ud5c8\ubca0\uc774\uacfc\uae30\ub300 \uce21 \uc870\uc0ac\uc704\ub294 \ud55c \uad50\uc218\uc758 \ub17c\ubb38\uc5d0 \ub2f4\uae34 \uc5f0\uad6c \uacb0\uacfc\uac00 \uc7ac\ud604\ub418\uc9c0 \uc54a\ub294\ub2e4\ub294 \uc810\uc740 \uc778\uc815\ud558\uba74\uc11c\ub3c4 \uc758\ub3c4\uc801\uc778 \uc870\uc791 \uac00\ub2a5\uc131\uc5d0 \ub300\ud574\uc11c\ub294 \ubd80\uc815\ud588\ub2e4. \ud55c \uad50\uc218\ub3c4 \ub17c\ubb38 \ucca0\ud68c\uc5d0 \ub300\ud574\uc120 \ubc1b\uc544\ub4e4\uc600\uc9c0\ub9cc, \ub17c\ubb38 \uc870\uc791 \uc758\ud639\uc5d0 \ub300\ud574\uc120 \uae30\uc874\uc758 \uc785\uc7a5\uc744 \uace0\uc218\ud588\ub2e4. \uadf8\ub294 \ud5c8\ubca0\uc774\uacfc\uae30\ub300\uac00 \ubc1c\ud45c\ud55c \uc785\uc7a5\ubb38\uc744 \ud1b5\ud574 \u201c\uc5f0\uad6c\uc5d0\uc11c \uc608\uc0c1\uce58 \ubabb\ud55c \uc624\ub958\ub4e4\uc774 \ubc1c\uc0dd\ud55c \uac83\uc774\uc9c0\ub9cc \ubd88\ud544\uc694\ud55c \ubb38\uc81c\ub97c \uc77c\uc73c\ud0a8 \uac83\uc5d0 \ub300\ud574 \uacfc\ud559\uacc4\uc640 \ub300\uc911\uc5d0 \uc0ac\uacfc\ub4dc\ub9b0\ub2e4\u201d\uace0 \ubc1d\ud614\ub2e4.<\/p>\n

 <\/p>\n

<\/span><\/p>\n

\uc911\uad6d \ud5c8\ubca0\uc774\uacfc\ud559\uae30\uc220\ub300. – \uc0ac\uc774\uc5b8\uc2a4<\/em><\/span><\/p>\n

 <\/p>\n

\u25cb \ub04a\uc774\uc9c0 \uc54a\ub294 \ub17c\ubb38 \uc870\uc791 \ub17c\ub780\u2026\u4e2d \uc5b8\ub860 \u201c1\ub144 \uc870\uc0ac\uacb0\uacfc\uac00 \uc9e7\uc740 \uc785\uc7a5\ubb38\u201c \ube44\ud310<\/strong><\/p>\n

\uadf8\ub7ec\ub098 \ud55c \uad50\uc218\ub97c \ub458\ub7ec\uc2fc \ub17c\ubb38 \uc870\uc791 \ub17c\ub780\uc740 \ub04a\uc774\uc9c0 \uc54a\uc744 \uac83\uc73c\ub85c \ubcf4\uc778\ub2e4. \ub300\ud559 \uce21 \uc870\uc0ac\uc704\uac00 \ub17c\ubb38\uc774 \ucca0\ud68c\ub418\uace0 \ub09c \ub4a4\uc5d0\uc57c \ub4a4\ub2a6\uac8c \uc9c4\uc0c1 \uc870\uc0ac\uc5d0 \ucc29\uc218\ud55c \ub370\ub2e4 \uacf5\uc2dd \uc785\uc7a5\ub9cc \ub0b4\ub1a8\uc744 \ubfd0, \uad6c\uccb4\uc801\uc778 \uc870\uc0ac \uacb0\uacfc\ub97c \uacf5\uac1c\ud558\uc9c0 \uc54a\uc558\uae30 \ub54c\ubb38\uc774\ub2e4.<\/p>\n

\uc911\uad6d \ub9e4\uccb4\uc778\u00a0jqk<\/span>\ub274\uc2a4\ub294 \u201c\uc9c0\ub09c\ud574 8\uc6d4 \uc870\uc0ac\uc704\ub97c \uafb8\ub9b0 \uc774\ud6c4 \uc774\ubc88 \ubc1c\ud45c\uac00 \uc788\uae30\uae4c\uc9c0 \ud5c8\ubca0\uc774\uacfc\uae30\ub300 \uce21\uc774 \uc870\uc0ac \uacfc\uc815\uc5d0 \ub300\ud55c \uc5b4\ub5a4 \ub0b4\uc6a9\ub3c4 \ubc1d\ud788\uc9c0 \uc54a\uc558\ub2e4\u201c\uba70 \u201c\uc870\uc0ac\uac00 \uc81c\ub300\ub85c \uc774\ub904\uc84c\ub294\uc9c0\uc870\ucc28 \uc758\uc2ec\uc2a4\ub7fd\ub2e4\u201d\uace0 \uc9c0\uc801\ud588\ub2e4. \ucc28\uc774\ub098\ub370\uc77c\ub9ac\ub3c4 \u201c1\ub144 \uc5ec\uac04\uc744 \uae30\ub2e4\ub9b0 \uc870\uc0ac \uacb0\uacfc\uac00 \uc9e7\uc740 \uc785\uc7a5\ubb38\uc5d0 \uadf8\ucce4\ub2e4\u201d\uace0 \ube44\ud310\ud588\ub2e4.<\/p>\n

\uad6d\uc81c\ud559\uc220\uc9c0 \u2018\ud504\ub860\ud2f0\uc5b4\uc2a4 \uc624\ube0c \uba54\ub514\uceec \uc0ac\uc774\uc5b8\uc2a4\u2019\uc758 \uc790\uc624\uc9c0\uc559\ud398\uc774 \ud3b8\uc9d1\uc7a5\ub3c4 \u201c\ud5c8\ubca0\uc774\uacfc\uae30\ub300 \uce21\uc740 \uc815\uc791 \u2018\uc65c \ud55c \uad50\uc218\uac00 \ub17c\ubb38\uc758 \uc624\ub958\ub97c \ucc98\uc74c\uc5d4 \uc778\uc815\ud558\uc9c0 \uc54a\ub2e4\uac00 \ub4a4\ub2a6\uac8c \uc2dc\uc778\ud588\ub294\uc9c0\u2019 \ub4f1\uc758 \ud575\uc2ec\uc801\uc778 \uc9c8\ubb38\uc5d0 \ub300\ud55c \ub2f5\uc740 \ub0b4\ub193\uc9c0 \uc54a\uc558\ub2e4\u201d\uace0 \uc9c0\uc801\ud588\ub2e4. \uc911\uad6d \uacfc\ud559\uacc4 \uc77c\uac01\uc5d0\uc11c\ub294 \uc774\ubc88 \uc0ac\ud0dc\ub97c \ub450\uace0 \uc5f0\uad6c\uc911\uc2ec\ub300\ud559\uc774 \uc544\ub2cc \ud5c8\ubca0\uc774\uacfc\uae30\ub300\uc5d0\uc11c\uae4c\uc9c0 \uad50\uc218\ub4e4\uc774 \uac70\uc561\uc758 \uc5f0\uad6c\ube44\ub97c \ub530\ub0b4\uae30 \uc704\ud574 \uacfc\uc695\uc744 \ubd80\ub9ac\uace0 \uc788\ub2e4\ub294 \uc9c0\uc801\ub3c4 \ub098\uc628\ub2e4.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

    (\uc6d0\ubb38)   But an investigation confirmed that the study was flawed.     A Chinese university has concluded that the authors of a(more…)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[32,33,29],"tags":[6,7,3],"class_list":["post-1559","post","type-post","status-publish","format-standard","hentry","category-essays-on-science","category-do-biology","category-lets-do-science","tag-essays-on-science","tag-do-biology","tag-lets-do-science"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":3988,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3988","url_meta":{"origin":1559,"position":0},"title":"The long shadow of a CRISPR scandal","author":"biochemistry","date":"August 3, 2019","format":false,"excerpt":"\u00a0 He Jiankui's controversial gene-editing experiment brought intense scrutiny to CRISPR scientists in China, and they're outraged. \u00a0 As He Jiankui strode to the podium at last year's summit on human genome editing in Hong Kong, China, more than 1 million people watched online. PHOTO: ANTHONY WALLACE\/AFP\/GETTY IMAGES \u00a0 \u00a0\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":976,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=976","url_meta":{"origin":1559,"position":1},"title":"CRISPR with a heart of gold helps ailing mice","author":"biochemistry","date":"June 28, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 \u00a0 Gene-editing molecules ride gold nanoparticles into the brain. \u00a0 Expression of a protein (blue-green, left) associated with fragile X syndrome is suppressed (right) in the brains of mice treated with CRISPR gene-editing molecules. Credit: B. Lee\u00a0et al.\/Nature\u00a0Biomed. Eng. \u00a0 \u00a0 Scientists are mining gold\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1313,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1313","url_meta":{"origin":1559,"position":2},"title":"Did CRISPR really fix a genetic mutation in these human embryos?","author":"biochemistry","date":"August 9, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 Researchers provide more evidence for their landmark claim that gene editing rid embryos of a disease mutation \u2014 but scientists are still arguing over the results. \u00a0 \u00a0 Eight-cell embryos injected with the gene editor CRISPR\u2013Cas9.Credit: H. Ma et al.\/Nature \u00a0 \u00a0 \u00a0 Biologists who\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1128,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1128","url_meta":{"origin":1559,"position":3},"title":"Gene editing gets a head start","author":"biochemistry","date":"July 17, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38: \uc5ec\uae30\ub97c \ud074\ub9ad\ud558\uc138\uc694~) \u00a0 \u00a0 Science\u00a0\u00a013 Jul 2018: Vol. 361, Issue 6398, pp. 142 DOI: 10.1126\/science.361.6398.142-b \u00a0 \u00a0 The development of gene-editing technologies into therapies for human disease is an exciting prospect. A crucial question is whether there are advantages to correcting disease-causing mutations before rather than after\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1535,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1535","url_meta":{"origin":1559,"position":4},"title":"Canine CRISPR trial raises \ufeffhopes for humans with deadly disease","author":"biochemistry","date":"September 2, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 Dogs with a disorder similar to Duchenne muscular dystrophy improve after gene-editing treatment. \u00a0 \u00a0 A powerful gene-editing technique can stimulate dogs\u2019 production of an important muscle protein, a finding that takes researchers a step closer to trying the technology in humans who have a\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3528,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3528","url_meta":{"origin":1559,"position":5},"title":"Brain in a dish, babies by design: what it means to be human","author":"biochemistry","date":"May 16, 2019","format":false,"excerpt":"\u00a0 \u00a0 Natalie Kofler is engrossed by a book that examines what cutting-edge biotechnology means for our sense of self. \u00a0 Neurons grown from the reprogrammed skin cells of science writer Philip Ball.Credit: Christopher Lovejoy\/Charlie Arber\/Selina Wray, University College London How to Grow a Human: Adventures in Who We Are\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on Science","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=32"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p9Xo1j-p9","_links":{"self":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/1559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1559"}],"version-history":[{"count":1,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/1559\/revisions"}],"predecessor-version":[{"id":4265,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=\/wp\/v2\/posts\/1559\/revisions\/4265"}],"wp:attachment":[{"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biochemistry.khu.ac.kr\/lab\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}