{"id":1482,"date":"2018-08-29T01:25:49","date_gmt":"2018-08-29T01:25:49","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=1482"},"modified":"2019-10-14T14:57:51","modified_gmt":"2019-10-14T05:57:51","slug":"%ec%86%8c%eb%a6%ac%e2%86%92%ec%a0%84%ea%b8%b0%ec%8b%a0%ed%98%b8-%eb%b3%80%ed%99%98-%ec%b2%ad%ea%b0%81-%ed%86%b5%eb%a1%9c-%eb%8b%a8%eb%b0%b1%ec%a7%88-%ea%b7%9c%eb%aa%85","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1482","title":{"rendered":"\u2018\uc18c\ub9ac\u2192\uc804\uae30\uc2e0\ud638 \ubcc0\ud658\u2019 \uccad\uac01 \ud1b5\ub85c \ub2e8\ubc31\uc9c8 \uaddc\uba85"},"content":{"rendered":"

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\ubbf8\uad6d \ud558\ubc84\ub4dc\uc758\ub300 \ub4f1 \uc5f0\uad6c\uc9c4 \ub17c\ubb38<\/b><\/p>\n

\ub2ec\ud33d\uc774\uad00 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\uc758 \uae30\ub2a5\uacfc \uad6c\uc870 \ubc1d\ud600<\/p>\n

\uc18c\ub9ac\uc790\uadf9 \ub54c \uc804\uae30\uc801 \ud750\ub984 \uc5ec\ub2eb\ub294 \ud1b5\ub85c \uad6c\uc2e4<\/p>\n

\uc18c\ub9ac\ub97c \uc804\uae30\uc2e0\ud638\ub85c \ubcc0\ud658\ud574 \ub1cc\uc5d0 \uc2e0\ud638 \uc804\ub2ec<\/p>\n

\u201c\uc624\ub79c \ub17c\ub780 \ub05d\ub0bc \uba85\ud655\ud55c \uc99d\uac70 \ud655\uc778\u201d<\/p>\n

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\ub1cc\uc5d0\uc11c \uc18c\ub9ac\ub97c \uc9c0\uac01\ud558\ub824\uba74, \uc18c\ub9ac \uc790\uadf9\uc740 \uba3c\uc800 \uc0dd\ubb3c\ud559\uc801\uc778 \uc804\uae30\uc2e0\ud638\ub85c \ubc14\ub00c\uc5b4 \ub1cc \uc2e0\uacbd\uc5d0 \uc804\ub2ec\ub3fc\uc57c \ud55c\ub2e4. \uc18c\ub9ac\uac00 \uc804\uae30\uc2e0\ud638\ub85c \ubc14\ub00c\ub294 \ubcc0\ud658 \uacfc\uc815\uc774 \uc788\uc5b4\uc57c \ud55c\ub2e4\ub294 \uac83\uc774\ub2e4. \ud558\uc9c0\ub9cc \uccad\uac01 \uc138\ud3ec \uc5f0\uad6c\uc758 \uc5b4\ub824\uc6c0 \ub54c\ubb38\uc5d0 \uccad\uac01\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uc740 \uc544\uc9c1 \uc0dd\ud654\ud559 \uc218\uc900\uae4c\uc9c0 \ucda9\ubd84\ud788 \uaddc\uba85\ub418\uc9c0 \ubabb\ud588\ub2e4\uace0 \ud55c\ub2e4. \uc18d\uadc0(\ub0b4\uc774)\uc5d0 \uc788\ub294 \ub2ec\ud33d\uc774\uad00\uc758 \uc720\ubaa8\uc138\ud3ec\ub4e4(hair<\/span>\u00a0cells<\/span>)\uc774 \uc18c\ub9ac \uc790\uadf9\uc744 \ub1cc\uc5d0 \uc804\ub2ec\ud558\ub294 \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4\uc9c0\ub9cc, \uadf8 \uc720\ubaa8\uc138\ud3ec\uc758 \ub2e8\ubc31\uc9c8\ub4e4 \uc911 \uc5b4\ub290 \uac83\uc774 \uc2e0\ud638 \ubcc0\ud658\uc758 \ud575\uc2ec \uc5ed\ud560\uc744 \ud558\ub294\uc9c0\ub294 \uc2e4\ud5d8 \uc99d\uac70\ub85c \uba85\ud655\ud788 \uc81c\uc2dc\ub418\uc9c0 \ubabb\ud588\uae30 \ub54c\ubb38\uc774\ub2e4.<\/p>\n

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\ubbf8\uad6d \ud558\ubc84\ub4dc \uc758\ub300 \uc18c\uc18d \uc81c\ud504\ub9ac \ud640\ud2b8 \ub4f1 \uacf5\ub3d9\uc5f0\uad6c\uc9c4\uc740 \ub2ec\ud33d\uc774\uad00 \uc720\ubaa8\uc138\ud3ec\uc5d0 \uc788\ub294 \ub2e8\ubc31\uc9c8 \ud2f0\uc5e0\uc2dc1(TMC<\/span>1, \uc720\uc804\uc790\u00a0Tmc<\/span>1)\uc774 \uc74c\ud30c \uc2e0\ud638\ub97c \uc804\uae30\uc2e0\ud638\ub85c \ubc14\uafb8\uc5b4 \ub1cc \uc2e0\uacbd\uc5d0 \uc804\ub2ec\ud558\ub294 \ub370 \uc911\uc694\ud55c \uad00\ubb38 \uad6c\uc2e4\uc744 \ud55c\ub2e4\ub294 \uac83\uc744 \uc2e4\ud5d8\uc73c\ub85c \uc785\uc99d\ud588\ub2e4\uba70, \uadf8 \uacb0\uacfc\ub97c\u00a0\uacfc\ud559\uc800\ub110 <\ub274\ub7f0>\uc5d0 \ubcf4\uace0<\/span>\ud588\ub2e4. \uc2e4\ud5d8\uc5d0\uc11c\ub294, \uc138\ud3ec\ub9c9\uc5d0 \uc788\ub294 \ub2e8\ubc31\uc9c8 \ud2f0\uc5e0\uc2dc1\uc774 \uc30d \uad6c\uc870\ub97c \uc774\ub8e8\uc5b4 \uc18c\ub9ac\ub098 \uba38\ub9ac \uc6c0\uc9c1\uc784 \uac19\uc740 \uc5ed\ud559\uc801 \uc790\uadf9\uc774 \uc788\uc744 \ub54c \uc138\ud3ec\ub9c9 \uc548\ud30e\uc758 \uc804\uae30\uc801 \ud750\ub984\uc744 \uc5f4\uace0 \ub2eb\ub294 \ud1b5\ub85c \ub2e8\ubc31\uc9c8\uc758 \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4\uace0 \ud55c\ub2e4. \uc989 \uc138\ud3ec\ub9c9\uc5d0\uc11c \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc758 \ud1b5\ub85c \uad6c\uba4d\uc774 \uc5f4\ub9ac\uace0 \ub2eb\ud798\uc73c\ub85c\uc368 \uce7c\uc298 \uc774\uc628\uacfc \ub098\ud2b8\ub968 \uc774\uc628\uc774 \uc138\ud3ec \uc548\ud30e\uc744 \ub4dc\ub098\ub4e4\uc5b4 \ub1cc \uc2e0\uacbd\uc5d0 \uc804\ub2ec\ub420 \uc804\uae30\uc2e0\ud638 \uc0dd\uc131\uc774 \uc870\uc808\ub41c\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n

\uc0ac\uc2e4, \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc774 \uc774\ubc88\uc5d0 \ucc98\uc74c \uc8fc\ubaa9\ubc1b\uc740 \uac83\uc740 \uc544\ub2c8\ub77c\uace0 \ud55c\ub2e4. \uc774 \ub2e8\ubc31\uc9c8\uc740 20002\ub144\uc5d0 \uccad\uac01\uacfc \uad00\ub828\ud55c \ub2e8\ubc31\uc9c8\ub85c \uc774\ubbf8 \ubcf4\uace0\ub418\uc5c8\uc73c\uba70, 2011\ub144\uc5d0\ub294 \uccad\uac01 \uc2e0\ud638 \ubcc0\ud658\uc5d0 \ud544\uc218\uc801\uc778 \ub2e8\ubc31\uc9c8\uc774\ub77c\ub294 \uc5f0\uad6c\uacb0\uacfc\ub3c4 \ubcf4\uace0\ub410\ub2e4. \uc9c0\ub09c\ud574\uc5d0\ub294 \ud06c\ub9ac\uc2a4\ud37c \uc720\uc804\uc790\uac00\uc704 \uae30\ubc95\uc744 \uc368\uc11c \uccad\ub825\uc190\uc2e4 \uc9c8\ud658 \ubaa8\ub378 \uc950\uc758 \uadc0\uc5d0\uc11c \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc758 \uc720\uc804\uc790\ub97c \ubcc0\ud615\ud568\uc73c\ub85c\uc368\u00a0\uccad\ub825\uc0c1\uc2e4 \uc99d\uc0c1\uc744 \ub2a6\ucd9c \uc218 \uc788\uc5c8\ub2e4\ub294<\/span>\u00a0\ubcf4\uace0\ub3c4 \uc788\uc5c8\ub2e4. \uc774\ucc98\ub7fc \ud2f0\uc5e0\uc2dc1\uc774 \uccad\uac01\uacfc \uad00\ub828\ud574 \uc911\uc694 \uc720\uc804\uc790 \ub610\ub294 \ub2e8\ubc31\uc9c8\ub85c \uc54c\ub824\uc838 \uc654\uc73c\ub098, \uadf8\uac83\uc774 \uc18c\ub9ac \uc790\uadf9 \ub54c\uc5d0 \uc2e4\uc81c\ub85c \uc804\uae30\uc2e0\ud638\ub97c \uc0dd\uc131\ud558\ub294 \u2018\ud1b5\ub85c \ub2e8\ubc31\uc9c8(\uc774\uc628\ucc44\ub110)\u2019\uc758 \uae30\ub2a5\uc744 \ud558\ub294\uc9c0\uc5d0 \uad00\ud574\uc11c\ub294 \uc2e4\ud5d8 \uc99d\uac70\uac00 \ucda9\ubd84\ud558\uc9c0 \uc54a\uc544 \ub17c\ub780\uc774 \uc774\uc5b4\uc838 \uc654\ub2e4\uace0 \ud55c\ub2e4.<\/p>\n

\uc5f0\uad6c\uc9c4\uc740 \uc774\ubc88 \uc5f0\uad6c\uacb0\uacfc\uac00 \ud2f0\uc5e0\uc2dc1\uc758 \uae30\ub2a5\uc744 \ud655\uc778\ud558\ub294 \uc2e4\ud5d8 \uc99d\uac70\uac00 \ub418\uba70, \ud2f0\uc5e0\uc2dc1\uc758 \uae30\ub2a5\uc744 \ub458\ub7ec\uc2f8\uace0 \ubc8c\uc5b4\uc9c4 \uadf8\ub3d9\uc548\uc758 \ub17c\ub780\uc744 \ub05d\ub0bc \ub9cc\ud55c \ubd84\uba85\ud55c \uc99d\uac70\uac00 \ub418\ub9ac\ub77c\uace0\u00a0\ud558\ubc84\ub4dc\ub300\ud559 \ub9e4\uccb4 <\uac00\uc81c\ud2b8>\uc5d0<\/span>\u00a0\ubc1d\ud614\ub2e4.<\/p>\n

<\uac00\uc81c\ud2b8>\uc640\u00a0<\ud3ec\ube0c\uc2a4>\uc758 \ubcf4\ub3c4<\/span>\ub97c \ubcf4\uba74, \uc5f0\uad6c\uc9c4\uc740 \uba3c\uc800 \uad6c\uc870\uac00 \uc720\uc0ac\ud55c \ub2e4\ub978 \ud1b5\ub85c \ub2e8\ubc31\uc9c8(\u2018TMEM<\/span>16\u2019)\uc5d0 \uae30\ubc18\uc744 \ub454 \ucef4\ud4e8\ud130 \ubaa8\ud615 \ubd84\uc11d\uc744 \ud1b5\ud574\uc11c, \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc744 \uad6c\uc131\ud558\ub294 \uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4 \uad6c\uc870\uc5d0\uc11c \uc804\uae30\uc2e0\ud638 \ud750\ub984\uc758 \ud1b5\ub85c \uad6c\uba4d\uc774 \ub420 \ub9cc\ud55c \uc544\ubbf8\ub178\uc0b0 \uc9c0\uc810 17\uacf3\uc744 \ud6c4\ubcf4\ub85c \uc608\uce21\ud574\ub0c8\ub2e4. \uc774\uc5b4 \uadf8 \uc9c0\uc810\uc758 \ubcf8\ub798 \uc544\ubbf8\ub178\uc0b0\uc744 \ub2e4\ub978 \uac83\uc73c\ub85c \ubc14\uafb8\ub294 17\uac00\uc9c0\uc758 \ub3cc\uc5f0\ubcc0\uc774\ub97c \ud558\ub098\uc529 \ub9cc\ub4e0 \ub2e4\uc74c\uc5d0 \uadf8 \uac01\uac01\uc758 \ub3cc\uc5f0\ubcc0\uc774 \ub2e8\ubc31\uc9c8\uc774 \uc2e4\ud5d8\uc6a9 \uc950\uc758 \uc720\ubaa8\uc138\ud3ec\ub4e4\uc5d0\uc11c \uac01\uac01 \ubc1c\ud604\ud558\uac8c \ud588\ub2e4. \uadf8\ub7ec\uace0\uc11c \uc18c\ub9ac \uc790\uadf9\uc774 \uc788\uc744 \ub54c \uc0dd\uc131\ub418\ub294 \uc804\uae30\uc2e0\ud638\uc758 \ud750\ub984\uc5d0 \uc5b4\ub5a4 \ubcc0\ud654\uac00 \ub098\ud0c0\ub098\ub294\uc9c0\ub97c \uac01\uac01 \uce21\uc815\ud574 \ub3cc\uc5f0\ubcc0\uc774 \uc5c6\ub294 \uc815\uc0c1 \ub2e8\ubc31\uc9c8\uacfc \ube44\uad50\ud588\ub2e4.<\/p>\n

\ub3cc\uc5f0\ubcc0\uc774\ub97c \uc774\uc6a9\ud55c \uc2e4\ud5d8\ubc29\ubc95\uc740 \uc774 \ub2e8\ubc31\uc9c8\uc744 \uad6c\uc131\ud558\ub294 \uae34 \uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4 \uad6c\uc870\uc5d0\uc11c \ud2b9\uc815 \uc9c0\uc810 \uc544\ubbf8\ub178\uc0b0\uc744 \uc77c\ubd80\ub85c \ubcf8\ub798 \uac83\uc5d0\uc11c \ub2e4\ub978 \uac83\uc73c\ub85c \ubc14\uafc0 \ub54c \ub098\ud0c0\ub098\ub294 \uae30\ub2a5\uc758 \ubcc0\ud654\ub97c \uad00\ucc30\ud568\uc73c\ub85c\uc368 \uadf8 \uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4 \uc9c0\uc810\uc758 \ubcf8\ub798 \uae30\ub2a5\uc744 \ud655\uc778\ud558\uae30 \uc704\ud55c \uac83\uc774\ub2e4. \ub2e4\uc74c\uc740 \uc5f0\uad6c\uc9c4\uc774 <\uac00\uc81c\ud2b8>\uc5d0 \uc804\ud55c \uc124\uba85\uc774\ub2e4.<\/p>\n

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\u201c(\uc774\ub7f0 \uc2e4\ud5d8\ubc29\ubc95\uc740 \uc5b4\ub5a4 \uc5d4\uc9c4 \uac01 \ubd80\ud488\uc774 \uc5b4\ub5bb\uac8c \uc791\ub3d9\ud558\ub294\uc9c0\ub97c \ud30c\uc545\ud558\uae30 \uc704\ud574 \uc5d4\uc9c0\ub2c8\uc5b4\uac00 \ud589\ud558\ub294 \uac83\uacfc \ube44\uc2b7\ud558\ub2e4.) \uc720\ubaa8\uc138\ud3ec\ub3c4 \uc790\ub3d9\ucc28 \uc5d4\uc9c4\ucc98\ub7fc \uac00\ub3d9\ub418\ub294 \ub3d9\uc548\uc5d0 \uc0b4\ud3b4\ubcf4\uc544\uc57c \ud55c\ub2e4. \ud53c\uc2a4\ud1a4\uc774\ub098 \uc810\ud654\ud50c\ub7ec\uadf8 \uadf8 \uc790\uccb4\ub9cc\uc73c\ub85c \uadf8\uac83\uc774 \uac01\uac01 \uc5b4\ub5bb\uac8c \uc791\ub3d9\ud558\ub294\uc9c0\ub97c \ud30c\uc545\ud560 \uc218\ub294 \uc5c6\ub2e4. \uac01 \ubd80\ud488\uc744 \ubcc0\uacbd\ud574 \uc5d4\uc9c4\uc5d0 \ub2e4\uc2dc \uc9d1\uc5b4\ub123\uc744 \ub54c\uc5d0, \ub098\ud0c0\ub098\ub294 \ud6a8\uacfc\ub97c \uc0b4\ud3b4\ubcf4\uc544\uc57c \ud55c\ub2e4.\u201d<\/p>\n

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\uc2e4\ud5d8\uacb0\uacfc\uc5d0\uc11c\ub294, \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc758 17\uac1c \ub3cc\uc5f0\ubcc0\uc774 \uc911 5\uac1c \ub3cc\uc5f0\ubcc0\uc774\uc5d0\uc11c \uc804\uae30\uc2e0\ud638 \ud750\ub984\uc774 \ucd5c\ub300 80%\uac00\ub7c9 \uc904\uc5b4\ub4e4\uc5c8\uc73c\uba70 \ud2b9\ud788 \ub2e4\ub978 1\uac1c \ub3cc\uc5f0\ubcc0\uc774\uc5d0\uc11c\ub294 \uc804\uae30\uc2e0\ud638\uac00 \uc544\uc608 \ucc28\ub2e8\ub418\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \uc989 \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc5d0\uc11c \ud2b9\uc815 \uc544\ubbf8\ub178\uc0b0 \uc11c\uc5f4 \uc9c0\uc810\ub4e4\uc5d0 \ubcc0\uc774\uac00 \uc0dd\uae38 \ub54c \uc804\uae30\uc2e0\ud638 \uc0dd\uc131\uc774 \ud06c\uac8c \uc904\uac70\ub098 \ucc28\ub2e8\ub41c\ub2e4\ub294 \uac83\uc774\ub2e4. \ub2ec\ub9ac \ub9d0\ud558\uba74, \uadf8\ub7f0 \uac10\uc18c \ub610\ub294 \ucc28\ub2e8 \ud6a8\uacfc\ub97c \uc77c\uc73c\ud0a8 \ub3cc\uc5f0\ubcc0\uc774 \uc9c0\uc810\uc774 \uc18c\ub9ac\ub97c \uc804\uae30\uc2e0\ud638\ub85c \ubcc0\ud658\ud558\ub294 \ub370 \ud575\uc2ec\uc801\uc778 \ud1b5\ub85c \uad6c\uba4d\uc758 \uad6c\uc2e4\uc744 \ud55c\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n

\uc5f0\uad6c\uc9c4\uc740 \u201c\uc774\ubc88 \uc5f0\uad6c\uacb0\uacfc\ub294 \ud2f0\uc5e0\uc2dc1\uc774 \uc18c\ub9ac\uc640 \uba38\ub9ac\uc6b4\ub3d9\uc744 \ub1cc\uc2e0\uacbd\uc774 \uc774\ud574\ud560 \uc804\uae30\uc2e0\ud638\ub85c \ubcc0\ud658\ud574\uc8fc\ub294 \uc911\ub300\ud55c \ubd84\uc790\uc13c\uc11c\uc784\uc744 \uba85\ud655\ud788 \uc785\uc99d\ud574\uc900\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4. \ud2f0\uc5e0\uc2dc1\ub294 \ud3ec\uc720\ub958\ubfd0 \uc544\ub2c8\ub77c \uc870\ub958, \uc5b4\ub958 \ub4f1 \ub3d9\ubb3c\uc5d0 \ub110\ub9ac \uac04\uc9c1\ub41c \uccad\uac01 \uad00\ub828 \uc720\uc804\uc790\ub85c \uc54c\ub824\uc838\uc654\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \ud2f0\uc5e0\uc2dc1\ub9cc\uc774 \uc18c\ub9ac\ub97c \uc804\uae30\uc2e0\ud638\ub85c \ubcc0\ud658\ud558\ub294 \u2018\uc720\uc77c\ud55c\u2019 \ud1b5\ub85c \ub2e8\ubc31\uc9c8\uc778\uc9c0\ub294 \ucd5c\uc885 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\ub2e4. \ube44\uc2b7\ud55c \uad6c\uc2e4\uc744 \ud558\ub294 \uc5ec\ub7ec \ub2e8\ubc31\uc9c8\ub4e4 \uc911 \ud558\ub098\uc77c \uc218\ub3c4 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4. \uadf8\ub807\ub354\ub77c\ub3c4 \uc774\ubc88 \uc2e4\ud5d8\uacb0\uacfc\ub294 \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc758 \uc8fc\uc694\ud55c \uc544\ubbf8\ub178\uc0b0 \uc9c0\uc810\uc5d0 \ubcc0\uc774\uac00 \uc77c\uc5b4\ub098 \ud2b9\uc815 \uc9c0\uc810\uc758 \uad6c\uc870\uc5d0 \ubcc0\ud654\uac00 \uc0dd\uae30\uba74 \uc18c\ub9ac \uc790\uadf9\uc774 \uc788\ub354\ub77c\ub3c4 \uc804\uae30\uc2e0\ud638\uac00 \uc0dd\uc131\ub418\uc9c0 \uc54a\uc544 \ub1cc \uc2e0\uacbd\uc5d0\uc11c \uc18c\ub9ac\ub97c \uc9c0\uac01\ud560 \uc218 \uc5c6\ub294 \uccad\ub825\uc0c1\uc2e4\uc774 \uc0dd\uae38 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc900\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \ud2f0\uc5e0\uc2dc1 \ub2e8\ubc31\uc9c8\uc758 \uae30\ub2a5 \ud655\uc778\uc73c\ub85c \uccad\ub825\uc0c1\uc2e4 \uc99d\uc0c1\uacfc \uce58\ub8cc\ubc29\ubc95\uc5d0 \ub300\ud55c \uae30\ucd08\uc5f0\uad6c\uac00 \ud798\uc744 \uc5bb\uc744 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \uae30\ub300\ud588\ub2e4.<\/p>\n

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\n
\ub17c\ubb38 \ucd08\ub85d<\/b>\u00a0(\uc6b0\ub9ac\ub9d0 \ubc88\uc5ed)
\n\uc18d\uadc0(\ub0b4\uc774)\uc758 \uc720\ubaa8\uc138\ud3ec\ub4e4(hari<\/span>\u00a0cells<\/span>)\uc5d0\uc11c \uc5ed\ud559\uc801 \uac10\uac01\uc804\ub2ec \ucc44\ub110\uc758 \uacbd\ub85c\ub97c \ud615\uc131\ud558\ub294 \ub2e8\ubc31\uc9c8\uc774 \uc5b4\ub290 \uac83\uc778\uc9c0\ub294 \uc544\uc9c1 \ud655\uc778\ub418\uc9c0 \uc54a\uc558\ub2e4. \uc720\uc804\ud559\uc801, \ud574\ubd80\ud559\uc801, \uc0dd\ub9ac\ud559\uc801 \uc99d\uac70\ub294 \uc720\ubaa8\uc138\ud3ec\uc758 \uac10\uac01 \uc804\ub2ec\uc5d0\uc11c \u2018\uc138\ud3ec \ub9c9\uac04 \ud1b5\ub85c \uc720\uc0ac\ub2e8\ubc31\uc9c8 1, \uc989\u00a0TMC<\/span>1\uc758 \uc5ed\ud560\uc744 \ub4b7\ubc1b\uce68\ud558\uc9c0\ub9cc\u00a0TMC<\/span>\u00a0\ub2e8\ubc31\uc9c8\uc758 \ubd84\uc790 \uae30\ub2a5\uc740 \uc544\uc9c1 \uba85\ud655\ud788 \uaddc\uba85\ub418\uc9c0 \uc54a\uc558\ub2e4. \uc6b0\ub9ac \uc5f0\uad6c\uc9c4\uc740\u00a0TMC<\/span>1 \uc774\ud569\uccb4\ub97c \ub4b7\ubc1b\uce68\ud558\ub294 \uc0dd\ud654\ud559\uc801 \uc99d\uac70\ub97c \uc81c\uc2dc\ud55c\ub2e4. \uc544\uc6b8\ub7ec \uc774\ub7c9\uccb4\u00a0TMEM<\/span>16 \ud1b5\ub85c \ub2e8\ubc31\uc9c8\uacfc \uc720\uc0ac\ud568\uc744 \uc9c0\ub2cc\ub2e4\ub294 \uac83\uc744 \ub4b7\ubc1b\uce68\ud558\ub294 \uad6c\uc870 \ubd84\uc11d\uacfc \uc11c\uc5f4 \ubd84\uc11d\uc744 \uc81c\uc2dc\ud55c\ub2e4.\u00a0TMC<\/span>1\uc758 \ud1b5\ub85c \uad6c\uba4d \uc601\uc5ed\uc744 \uc2dd\ubcc4\ud558\uae30 \uc704\ud558\uc5ec, \uc6b0\ub9ac\ub294 \uc2dc\uc2a4\ud14c\uc778 \ub3cc\uc5f0\ubcc0\uc774 \uc720\ubc1c \uae30\ubc95\uc744 \uc0ac\uc6a9\ud558\uc5ec\u00a0Tmc<\/span>1\/2 \uc5c6\ub294 \ub9c8\uc6b0\uc2a4\uc758 \uc720\ubaa8\uc138\ud3ec\ub4e4\uc5d0\ub2e4\u00a0TMC<\/span>1 \ub3cc\uc5f0\ubcc0\uc774\ub97c \ubc1c\ud604\uc2dc\ucf30\ub2e4. \uc2dc\uc2a4\ud14c\uc778 \ubcc0\ud615 \uc2dc\uc57d\uc740 \uc5ed\ud559\uc801 \uac10\uac01 \uc804\ub2ec\uc758 \uc18d\uc131\uc744 \uc2e0\uc18d\ud558\uace0 \ube44\uac00\uc5ed\uc801\uc73c\ub85c \ubcc0\ud654\uc2dc\ucf30\ub2e4. \uc6b0\ub9ac\ub294\u00a0TMC<\/span>1\uc774\u00a0TMEM<\/span>16 \ud1b5\ub85c \ub2e8\ubc31\uc9c8\uacfc \uad6c\uc870\uc801\uc73c\ub85c \uc720\uc0ac\ud558\uba70, \ub610\ud55c \uac70\uae30\uc5d0\ub294 \ud1b5\ub85c\uad6c\uba4d\uc744 \ub530\ub77c 4\uac1c\uc758 \ub3c4\uba54\uc778, \uc989 S4~S7\uc744 \uac16\ucd98 10\uac1c\uc758 \ub9c9\uac04 \ub3c4\uba54\uc778\uc774 \ud3ec\ud568\ub3fc \uc788\uc74c\uc744 \uc81c\uc2dc\ud55c\ub2e4. \uc774\ub7f0 \ub370\uc774\ud130\ub294\u00a0TMC<\/span>1\uc774 \uccad\uac01 \ubc0f \uc804\uc815 \uc720\ubaa8\uc138\ud3ec\uc5d0\uc11c \uac10\uac01 \uc804\ub2ec \ud1b5\ub85c\uc758 \uad6c\uba4d\uc744 \ud615\uc131\ud558\ub294 \uc131\ubd84\uc774\ub77c\ub294 \uac15\ud55c \uc99d\uac70\ub97c \uc81c\uacf5\ud55c\ub2e4.[Neuron<\/span>,\u00a0https<\/span>:\/\/doi<\/span>.org<\/span>\/10.1016\/j.neuron<\/span>.2018.07.033<\/span>]<\/div>\n<\/div>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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\uc5ed\ud560\uc744 \ud558\ub294 \ubb3c\uc9c8\uc774\ub2e4. \ucd5c\uadfc \uc911\uad6d\uacfc \ubbf8\uad6d \uc5f0\uad6c\uc790\ub4e4\uc774\u00a0RNA\uc758\u2026","rel":"","context":"In "Let's Do Biology!"","block_context":{"text":"Let's Do Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":3034,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=3034","url_meta":{"origin":1482,"position":5},"title":"\ub1cc\ub97c \uc18d\uc774\ub294 \ucc29\uc2dc \ud604\uc0c1","author":"biochemistry","date":"March 29, 2019","format":false,"excerpt":"\u00a0 \u00a0 [\uc694\uc57d]\ubbf8\uad6d \uce98\ub9ac\ud3ec\ub2c8\uc544\uacf5\uacfc\ub300\ud559(\uce7c\ud14d) \uc5f0\uad6c\uc9c4\uc774 \uc778\uc704\uc801\uc73c\ub85c \ucc29\uc2dc\ud604\uc0c1\uc744 \uc77c\uc73c\ud0b4\uc73c\ub85c\uc368 \uc6b0\ub9ac \ub1cc\uac00 \uc11c\ub85c \ub2e4\ub978 \uac10\uac01\uc744 \uc5b4\ub5bb\uac8c \ubc1b\uc544\ub4e4\uc774\uace0 \ucc98\ub9ac\ud558\ub294\uc9c0\uc5d0 \ub300\ud55c \ub2e8\uc11c\ub97c \ubc1c\uacac\ud588\ub2e4. \uc6b0\ub9ac \ub1cc\ub294 \ucc98\uc74c \uac10\uac01 \uc2e0\ud638\ub97c \ucc98\ub9ac\ud558\uae30 \uc774\uc804\uc5d0, \ub2e4\ub978 \uc790\uadf9\uc774 \ub4e4\uc5b4\uc624\uac8c \ub418\uba74 \uc774\ub97c \uad6c\ubcc4\ud574\ub0b4\uc9c0 \ubabb\ud55c\ub2e4. \uacb0\uad6d \ub1cc\ub294 '\uc0ac\ud6c4\ucc98\ub9ac' \uacfc\uc815\uc744 \ud1b5\ud574 \uc0ac\uc2e4\uc774 \uc544\ub2cc \uac83\uc744 \ud604\uc2e4\uc774\ub77c\uace0 \ud310\ub2e8\ud558\uac8c \ub41c\ub2e4.(2018.10) \u00a0 \uc9e7\uc740 \uc2dc\uac04 \uc12c\uad11\uacfc \uc18c\ub9ac(BEEP)\ub97c \ubcf4\uc5ec\uc8fc\uba74\u2026","rel":"","context":"In "Essays on Science"","block_context":{"text":"Essays on 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