{"id":1347,"date":"2018-08-13T02:52:39","date_gmt":"2018-08-13T02:52:39","guid":{"rendered":"http:\/\/163.180.4.222\/lab\/?p=1347"},"modified":"2019-10-14T14:59:12","modified_gmt":"2019-10-14T05:59:12","slug":"%ec%9c%a0%ec%a0%84%ec%9e%90%ea%b0%80%ec%9c%84%eb%8a%94-%eb%a7%8c%eb%8a%a5%ec%95%88%ec%a0%84%ec%84%b1-%ea%b2%bd%ea%b3%a0-%ec%9e%87%eb%94%b0%eb%9d%bc","status":"publish","type":"post","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1347","title":{"rendered":"\uc720\uc804\uc790\uac00\uc704\ub294 \ub9cc\ub2a5?\u2026\uc548\uc804\uc131 \uacbd\uace0 \uc787\ub530\ub77c"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>(<a href=\"http:\/\/www.hani.co.kr\/arti\/science\/science_general\/857327.html\">\uc6d0\ubb38<\/a>)<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><b>\uc720\uc804\uc790\uce58\ub8cc \uc548\uc804\uc131 \uc5f0\uad6c \uc5b4\ub514\uae4c\uc9c0<\/b><\/p>\n<p>\uc720\uc804\uc790\uac00\uc704, \uc815\ud655\ud788 \ud45c\uc801 \uc798\ub77c\ub3c4<\/p>\n<p><span class=\"word_dic en\">DNA<\/span>\u00a0\uacb0\uc2e4\u00b7\uc0bd\uc785\u00b7\uc7ac\ubc30\uc5f4 \ubd80\uc791\uc6a9<\/p>\n<p>\ubcc0\uc774\uc720\ubc1c \uba54\ucee4\ub2c8\uc998 \uaddc\uba85 \uc0c8 \uacfc\uc81c<\/p>\n<p>\uac00\uc704 \uc791\ub3d9 \uc774\ud6c4 \uc138\ud3ec \ub300\uc751 \ubcf5\uc7a1<\/p>\n<p>\uc554 \uc704\ud5d8\uacfc\uc758 \uc0c1\uad00\uc131 \ud655\uc778\ub418\uae30\ub3c4<\/p>\n<p>\uc9c0\ub098\uce5c \ub099\uad00 \uc55e\uc11c \ud604\uc2e4\uc801 \uc811\uadfc\uc744<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span class=\"end_photo_org\"><img decoding=\"async\" src=\"https:\/\/imgnews.pstatic.net\/image\/028\/2018\/08\/13\/0002421018_001_20180813104018041.JPG?type=w647\" \/><\/span><\/p>\n<p><span class=\"end_photo_org\"><em class=\"img_desc\">\uc778\uac04 \uc904\uae30\uc138\ud3ec\uc5d0 \ub300\ud574 \uc720\uc804\uc790\uac00\uc704 \uae30\ubc95\uc73c\ub85c \uc720\uc804\uc790 \ud3b8\uc9d1\uc744 \uc2dc\ud589\ud55c \uc2e4\ud5d8\uc5d0\uc11c \uc758\ub3c4\ud558\uc9c0 \uc54a\uc740 \ubcc0\uc774\uac00 \uc0c1\ub2f9\ud55c \uaddc\ubaa8\ub85c \ub098\ud0c0\ub0ac\ub2e4\ub294 \uc5f0\uad6c\uacb0\uacfc\ub97c \ucd5c\uadfc \uc601\uad6d \uc0dd\uc5b4\uc5f0\uad6c\uc18c \uc5f0\uad6c\uc9c4\uc774 \ubc1c\ud45c\ud588\ub2e4. \uc0ac\uc9c4 \ucd9c\ucc98: \uc560\ub2c8 \uce90\ubc84\ub108, \uc6f0\ucef4\uc0dd\uc5b4\uc5f0\uad6c\uc18c(<span class=\"word_dic en\">CC<\/span>\u00a0<span class=\"word_dic en\">BY<\/span>\u00a0<span class=\"word_dic en\">NC<\/span>)<\/em><\/span>\u2018<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\ub09c\uce58 \uc9c8\ud658\uc744 \uace0\uce60 \ubbf8\ub798\uc758 \uc815\uad50\ud55c \uc720\uc804\uc790 \uce58\ub8cc\uc220\u2019\ub85c \ubd88\ub9ac\uace4 \ud558\ub294 \ud06c\ub9ac\uc2a4\ud37c \uc720\uc804\uc790\uac00\uc704(<span class=\"word_dic en\">CRISPR<\/span>&#8211;<span class=\"word_dic en\">Cas<\/span>9)\uac00 \uc2e4\uc81c \uc784\uc0c1\uce58\ub8cc\uc5d0 \uc548\uc804\ud558\uac8c \uc4f0\uc774\uae30 \uc804\uc5d0 \ub118\uc5b4\uc57c \ud560 \u2018\uc548\uc804\uc131\uc758 \uae30\uc900\u2019\uc774 \ub192\uc544\uc9c0\uace0 \uc788\ub2e4. \uc9c0\uae08\uae4c\uc9c0 \uc798 \uc54c\ub824\uc9c0\uc9c0 \uc54a\uc558\ub358 \uc720\uc804\uc790\uac00\uc704\uc758 \ubd80\uc791\uc6a9 \uac00\ub2a5\uc131\uc774 \ucd5c\uadfc \uc5f0\uad6c\ub4e4\uc5d0\uc11c \uc0c8\ub86d\uac8c \uc81c\uae30\ub418\uace0 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4. \uc8fc\uc758\ud558\uc9c0 \uc54a\ub294\ub2e4\uba74 \uc720\uc804\uc790\uac00\uc704\ub294\u00a0\uc778\uccb4 \uba74\uc5ed\uc5fc\uc99d \ubc18\uc751\uc744\u00a0\uc77c\uc73c\ud0ac \uc218 \uc788\uc73c\uba70,\u00a0\uc554 \uc704\ud5d8\uc744 \ub192\uc77c \uc218\ub3c4\u00a0\uc788\uace0, \uc608\uc0c1\ud558\uc9c0 \ubabb\ud55c\u00a0\ub514\uc5d4\uc5d0\uc774(<span class=\"word_dic en\">DNA<\/span>) \ubcc0\uc774\ub97c \uc720\ubc1c\ud560 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c\uacb0\uacfc\uac00 \uac01\uae30 \ub2e4\ub978 \uc5f0\uad6c\uc9c4\uc5d0 \uc758\ud574 \uc62c\ud574 \ub4e4\uc5b4 \ucd5c\uadfc\uae4c\uc9c0 \uc787\ub530\ub77c \uc81c\uae30\ub410\ub2e4.<\/p>\n<p>\uc774\ub7f0 \uc5f0\uad6c\uac00 \ucd5c\uadfc \ub4e4\uc5b4 \uc787\ub530\ub974\ub294 \uac83\uc740 \uc720\uc804\uc790\uac00\uc704\uac00 2013\ub144 \uc774\ud6c4 \uba87 \ub144 \ub9cc\uc5d0 \uae30\uc874 \uc720\uc804\uacf5\ud559\uc758 \uac70\uc758 \ubaa8\ub4e0 \uc601\uc5ed\uc5d0\uc11c \ub300\uc548\uc758 \ud601\uc2e0\uae30\uc220\ub85c \ud655\uc2e4\ud55c \uc601\ud5a5\ub825\uc744 \ud655\uc7a5\ud55c \ub370 \ube44\ud574, \uc9e7\uc740 \uc5ed\uc0ac\ub85c \uc778\ud574 \uc778\uccb4 \uc548\uc804\uc131 \uce21\uba74\uc740 \uadf8\ub3d9\uc548 \ucda9\ubd84\ud788 \ub2e4\ub904\uc9c0\uc9c0 \ubabb\ud588\uae30 \ub54c\ubb38\uc73c\ub85c \ud480\uc774\ub41c\ub2e4. \uc778\uccb4 \uc548\uc804\uc131 \uc5f0\uad6c\ub4e4\uc740 \uc720\uc804\uc790\uac00\uc704\uac00 \uc778\uccb4 \uce58\ub8cc\uc220\ub85c \ub098\uc544\uac00\uae30 \uc704\ud574 \ub118\uc5b4\uc57c \ud560 \uc548\uc804\uc131 \uae30\uc900\uc744 \ub192\uc5ec\uc8fc\uace0 \uc788\ub2e4\uace0 \uc5f0\uad6c\uc790\ub4e4\uc740 \ubcf4\uace0 \uc788\ub2e4. \uc720\uc804\uc790\uac00\uc704\uc758 \uc778\uccb4 \uc548\uc804\uc131\uacfc \uad00\ub828\ud574 \ucd5c\uadfc \uc5f0\uad6c\uacb0\uacfc\ub4e4\uc5d0\uc11c \uc5b4\ub5a4 \uc774\uc288\uac00 \ub17c\uc758\ub418\uace0 \uc788\uc744\uae4c?<\/p>\n<p>&nbsp;<\/p>\n<p><span class=\"end_photo_org\"><img decoding=\"async\" src=\"https:\/\/imgnews.pstatic.net\/image\/028\/2018\/08\/13\/0002421018_002_20180813104018063.JPG?type=w647\" \/><\/span><\/p>\n<p><b>\uc720\uc804\uc790\uac00\uc704 \uc791\ub3d9 \ub4a4 \uc138\ud3ec\uc5d0 \uc77c\uc5b4\ub098\ub294 \uc77c<\/b><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\ucd5c\uadfc \uc5f0\uad6c\ub4e4\uc740 \uc720\uc804\uc790\uac00\uc704\uac00 \uc815\ud655\ud788 \uc791\ub3d9\ud558\ub354\ub77c\ub3c4 \ub2e4\ub978 \ubd80\uc791\uc6a9\uc774 \uc0dd\uae38 \uac00\ub2a5\uc131\uc774 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc900\ub2e4\ub294 \uc810\uc5d0\uc11c \uc8fc\ubaa9\ubc1b\uace0 \uc788\ub2e4.<\/p>\n<p>\uc2a4\uc6e8\ub374\u00a0\uce74\ub864\ub9b0\uc2a4\uce74\uc5f0\uad6c\uc18c \ub4f1 \uc5f0\uad6c\uc9c4\uacfc \ubbf8\uad6d\u00a0\ub178\ubc14\ud2f0\uc2a4 \uc0dd\uba85\uc758\ud559\uc5f0\uad6c\uc18c \uc5f0\uad6c\uc9c4\uc740 \uac01\uac01 \uc720\uc804\uc790\uac00\uc704\uc640 \uc554 \uc704\ud5d8 \uac04\uc5d0 \uc0c1\uad00\uc131\uc774 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uc5f0\uad6c\uacb0\uacfc\ub97c \uc9c0\ub09c 6\uc6d4 &lt;\ub124\uc774\ucc98 \uba54\ub514\uc2e0&gt;\uc5d0 \ub098\ub780\ud788 \ubc1c\ud45c\ud588\ub2e4.<\/p>\n<p>\uc774 \uc5f0\uad6c\uc5d0\uc120 \uc554 \uc5b5\uc81c \uc720\uc804\uc790\ub85c \ub110\ub9ac \uc54c\ub824\uc9c4 \u2018\ud53c53\u2019(p53) \uc720\uc804\uc790\uac00 \uc911\uc694\ud558\uac8c \ub2e4\ub904\uc84c\ub2e4. \uc720\uc804\uc790 p53\uc740 \ub514\uc5d4\uc5d0\uc774\uc5d0 \uc190\uc0c1\uc774 \uc0dd\uacbc\uc744 \ub54c \ubcf5\uad6c \uacfc\uc815\uc5d0 \ucc38\uc5ec\ud574 \uc885\uc591\uc744 \uc5b5\uc81c\ud558\ub294 \uae30\ub2a5\uc744 \ud55c\ub2e4. \ub110\ub9ac \uc4f0\uc774\ub294 \uc720\uc804\uc790\uac00\uc704 \ubd84\uc790(<span class=\"word_dic en\">Cas<\/span>9)\ub294 \ub514\uc5d4\uc5d0\uc774 \ub450 \uac00\ub2e5\uc744 \uc808\ub2e8\ud558\ub294 \uc791\ub3d9\uc744 \ud558\ub294\ub370, \ub2f9\uc5f0\ud788 p53\uc740 \uc774\ub7f0 \uacfc\uc815\uc744 \uadf8\ub300\ub85c \ub450\uace0 \ubcf4\uc9c4 \uc54a\ub294\ub2e4. \uc720\uc804\uc790\uac00\uc704\uac00 \uc808\ub2e8\ud55c \ub514\uc5d4\uc5d0\uc774\ub97c \ubcf5\uad6c\ud558\uac70\ub098 \ubcc0\uc774\uac00 \uc2ec\ud558\uac8c \uc0dd\uacbc\uc744 \ub54c\uc5d4 \uc138\ud3ec \uc2a4\uc2a4\ub85c \uc8fd\uc74c\uc5d0 \uc774\ub974\uac8c \ub9cc\ub4e0\ub2e4. \uc0ac\uc815\uc774 \uc774\ub807\ub2e4 \ubcf4\ub2c8, \uc720\uc804\uc790\uac00\uc704\ub294 \uc138\ud3ec\uc758 \ubcf4\ud638\uc790\uc778 p53\uc774 \uae30\ub2a5\ud558\uc9c0 \ubabb\ud558\ub294 \ube44\uc815\uc0c1 \uc138\ud3ec\ub4e4\uc5d0\uc11c \ud6e8\uc52c \ub354 \uc798 \uc791\ub3d9\ud55c\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc9c4\uc740 \uc720\uc804\uc790\uac00\uc704\uac00 p53\uc774 \uc81c \uae30\ub2a5\uc744 \ud558\uc9c0 \ubabb\ud558\ub294 \uc138\ud3ec\uc5d0\uc11c \uc798 \uc791\ub3d9\ud558\uae30 \ub54c\ubb38\uc5d0, \uc720\uc804\uc790\uac00\uc704\ub97c \uac70\uce5c \uc138\ud3ec\ub97c \uc720\uc804\uc790\uce58\ub8cc\uc6a9\uc73c\ub85c \uc4f4\ub2e4\uba74 \uadf8 \uc138\ud3ec\ub4e4\uc5d0\uc11c\ub294 \uc885\uc591 \uc5b5\uc81c \uc720\uc804\uc790 p53\uc774 \uc81c\uac70\ub418\uc5b4 \uc554 \uc704\ud5d8\uc774 \ucee4\uc9c8 \uc218 \uc788\ub2e4\ub294 \uacb0\ub860\uc744 \uc81c\uc2dc\ud588\ub2e4. \uc720\uc804\uc790\uac00\uc704\ub85c \ub9cc\ub4e0 \uce58\ub8cc\uc6a9 \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud560 \ub54c\uc5d4 \uc774\ub7f0 \uc704\ud5d8\ub3c4 \ucda9\ubd84\ud788 \uc0b4\ud3b4\uc57c \ud55c\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n<p>\ud558\uc9c0\ub9cc \ud53c\ud560 \uc218 \uc5c6\ub294 \uc2ec\uac01\ud55c \ubb38\uc81c\ub294 \uc544\ub2c8\ub77c\uace0 \uc5f0\uad6c\uc790\ub4e4\uc740 \ubcf4\uace0 \uc788\ub2e4. \uc774\uc640 \uad00\ub828\ud574 \uae40\uc9c4\uc218 \uae30\ucd08\uacfc\ud559\uc5f0\uad6c\uc6d0 \uc720\uc804\uccb4\uad50\uc815\uc5f0\uad6c\ub2e8\uc7a5(\uc11c\uc6b8\ub300 \uad50\uc218)\uc740 \u201c\uc5b4\ub5a4 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c\ub3c4 p53 \uc720\uc804\uc790\uac00 \uc5c6\ub294 \uc138\ud3ec\ub4e4\uc744 \uce58\ub8cc\uc81c\ub85c \uc0ac\uc6a9\ud558\uc9c0\ub294 \uc54a\ub294\ub2e4\u201d\uba70 \u201c\uc190\uc27d\uac8c \ud655\uc778\ud560 \uc218 \uc788\uc73c\ubbc0\ub85c \ub300\ubd80\ubd84 \uc784\uc0c1 \uc5f0\uad6c\uc5d0\uc11c \uac78\ub9bc\ub3cc\uc774 \ub418\uc9c0\ub294 \uc54a\uc744 \uac83\u201d\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<p>\uc880 \ub354 \ubcf5\uc7a1\ud55c \ubb38\uc81c\ub294 \uc720\uc804\uc790\uac00\uc704\uac00 \uc815\ud655\ud558\uac8c \ub514\uc5d4\uc5d0\uc774\uc758 \ud45c\uc801\uc9c0\uc810\uc744 \ucc3e\uc544\uac00 \uc808\ub2e8\ud558\ub354\ub77c\ub3c4 \uc808\ub2e8 \uc9c0\uc810 \ubd80\uadfc\uc5d0\uc11c \uc608\uc0c1\ud558\uc9c0 \ubabb\ud55c \ubcc0\uc774\ub4e4\uc774 \uc0dd\uaca8\ub0a0 \uac00\ub2a5\uc131\uc774 \uc0c8\ub86d\uac8c \uc81c\uae30\ub410\ub2e4\ub294 \uc810\uc774\ub2e4.\u00a0\uc9c0\ub09c\ub2ec \uc601\uad6d \uc6f0\ucef4\uc0dd\uc5b4\uc5f0\uad6c\uc18c \uc5f0\uad6c\uc9c4\uc740\u00a0\uc720\uc804\uc790\uac00\uc704 \uae30\uc220\uc744 \uc2dc\ud589\ud55c \uc774\ud6c4\uc5d0 \uc950\uc640 \uc0ac\ub78c \uc138\ud3ec\ub4e4\uc758 \uc720\uc804\uccb4\uc5d0 \ub098\ud0c0\ub09c \uc5fc\uae30\uc11c\uc5f4 \ubcc0\uc774\ub97c \uc804\uc5d0 \uc5c6\ub358 \uae30\ubc95\uc73c\ub85c \uc815\ubc00\ud558\uac8c \ubd84\uc11d\ud574 \uadf8 \uacb0\uacfc\ub97c\u00a0&lt;\ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0&gt;\uc5d0\u00a0\ubc1c\ud45c\ud588\ub2e4.<\/p>\n<p>\uc774 \uc5f0\uad6c\uacb0\uacfc\uc5d0\uc11c\ub294, \uc720\uc804\uc790\uac00\uc704\uac00 \ud45c\uc801\uc9c0\uc810\uc744 \uc815\ud655\ud788 \uc808\ub2e8\ud558\ub354\ub77c\ub3c4 \uc774\ud6c4\uc5d0 \uc138\ud3ec\uc758 \uc790\uc5f0\uc2a4\ub7ec\uc6b4 \ubc18\uc751\uc73c\ub85c \ub514\uc5d4\uc5d0\uc774\ub97c \ubcf5\uad6c\ud558\ub294 \uacfc\uc815\uc5d0\uc11c \ub73b\ubc16\uc758 \uc5fc\uae30\uc11c\uc5f4 \uacb0\uc2e4, \uc0bd\uc785, \uc7ac\ubc30\uc5f4 \uac19\uc740 \ubcc0\uc774\ub4e4\uc774 \uc808\ub2e8 \uc9c0\uc810 \ubd80\uadfc\uc5d0\uc11c \ubb34\uc791\uc704\uc801\uc774\uace0 \ub300\ub7c9\uc73c\ub85c \uc77c\uc5b4\ub0a0 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \ub54c\ub85c\ub294 \ubcc0\uc774\uac00 \uc218\ubc31 \ub0b4\uc9c0 \uc218\ucc9c \uc5fc\uae30\uc30d \uaddc\ubaa8\ub85c\ub3c4 \uc77c\uc5b4\ub09c \uac83\uc73c\ub85c \ubcf4\uace0\ub410\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \u201c\uc720\uc804\uc790 \ud3b8\uc9d1\uc774 \uc54c\ub824\uc9c4 \uac83\ubcf4\ub2e4 \ud6e8\uc52c \ud070 \uc720\uc804\uccb4 \uc190\uc0c1\uc744 \uc77c\uc73c\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<p>\uadf8\ub3d9\uc548 \uc720\uc804\uc790\uac00\uc704\ub85c \uc778\ud55c \ubcc0\uc774\uc758 \ubb38\uc81c\ub85c\ub294 \uc8fc\ub85c \ud45c\uc801\uc9c0\uc810 \uc544\ub2cc \uacf3\uc744 \uc808\ub2e8\ud558\ub294\u00a0\u2018\ud45c\uc801\uc774\ud0c8\u2019\uc758 \ubb38\uc81c\uac00 \uc9c0\uc801\ub41c \ubc14 \uc788\ub294\ub370(\ud55c\uaca8\ub808 2017\ub144 7\uc6d431\uc77c\uce58 21\uba74), \uc774\ubc88 \uc0dd\uc5b4\uc5f0\uad6c\uc18c \uc5f0\uad6c\uc9c4\uc740 \ud45c\uc801 \uc9c0\uc810\uc5d0\uc11c\ub3c4 \uc0c1\ub2f9\ud55c \ubcc0\uc774\uac00 \uc77c\uc5b4\ub0a0 \uc218 \uc788\uc74c\uc744 \ucc98\uc74c \uc81c\uae30\ud588\ub2e4.<\/p>\n<p>\uae40\uc9c4\uc218 \ub2e8\uc7a5\uc740 &lt;\ub124\uc774\ucc98 \ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0&gt;\uc5d0 \uc4f4 \ud574\uc124\uc5d0\uc11c \u201c\uc774 \uc5f0\uad6c\ub294 \uccb4\uc138\ud3ec\uc640 \uc0dd\uc2dd\uc138\ud3ec \uc720\uc804\uc790\uce58\ub8cc\uc5d0\uc11c \ud06c\ub9ac\uc2a4\ud37c\ub098 \ub2e4\ub978 \uc720\uc804\uc790\uac00\uc704 \ub3c4\uad6c\ub97c \ub354 \uc548\uc804\ud558\uac8c \uc0ac\uc6a9\ud558\ub3c4\ub85d \ud558\ub294 \uc548\uc804\uc131 \uae30\uc900\uc744 \ud655\uc2e4\ud558\uac8c \ub192\uc5ec\uc8fc\uc5c8\ub2e4\u201d\uba74\uc11c \u201c\ubbf8\ub798 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc120 \ud45c\uc801\uc774\ud0c8 \ud6a8\uacfc\uc640 \ub354\ubd88\uc5b4 \ud45c\uc801\uc9c0\uc810\uc758 \uc608\uae30\uce58 \ubabb\ud55c \ubcc0\uc774\ub3c4 \uc8fc\uc758 \uae4a\uac8c \ubaa8\ub2c8\ud130\ub9c1\ud558\uace0 \uad00\ub9ac\ud574\uc57c \ud560 \uac83\u201d\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p><iframe loading=\"lazy\" src=\"https:\/\/www.youtube.com\/embed\/2pp17E4E-O8\" width=\"544\" height=\"316\" data-mce-fragment=\"1\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><b>\ub2e4\uc2dc \uc8fc\ubaa9\ubc1b\ub294\u00a0<span class=\"word_dic en\">DNA<\/span>\u00a0\uc808\ub2e8-\ubcf5\uad6c \uacfc\uc815<\/b><\/p>\n<p>\ucd5c\uadfc \uc548\uc804\uc131 \uc5f0\uad6c\ub4e4\uc774 \uc720\uc804\uc790\uac00\uc704\uc758 \ub514\uc5d4\uc5d0\uc774 \uc808\ub2e8 \uc774\ud6c4\uc5d0 \uc77c\uc5b4\ub098\ub294 \uc138\ud3ec\uc758 \ub514\uc5d4\uc5d0\uc774 \ubcf5\uad6c \uc2dc\uc2a4\ud15c\uc744 \uc8fc\ub85c \ub2e4\ub8e8\uba74\uc11c, \ub514\uc5d4\uc5d0\uc774 \ubcf5\uad6c \ubc29\uc2dd\uc5d0 \ub300\ud55c \uad00\uc2ec\ub3c4 \uc0c8\uc0bc \ub192\uc544\uc9c0\uace0 \uc788\ub2e4.\u00a0\uad00\ub828 \uc8fc\uc81c\ub97c \ub2e4\ub8e8\ub294 \uc5f0\uad6c\uacb0\uacfc\ub3c4 \uc774\uc804\ubcf4\ub2e4 \uc880 \ub354 \ub208\uc5d0 \ub748\ub2e4. \uc720\uc804\uc790\uac00\uc704\uc758 \uc791\ub3d9 \uc6d0\ub9ac\ub97c \uaddc\uba85\ud574\uc628 \ubc30\uc0c1\uc218 \ud55c\uc591\ub300 \uad50\uc218(\ud654\ud559)\ub294 \u201c\uc0dd\uc5b4\uc5f0\uad6c\uc18c \uc5f0\uad6c\uacb0\uacfc\ub294 \ub514\uc5d4\uc5d0\uc774 \ubcf5\uad6c \uacfc\uc815\uc5d0 \ub300\ud574 \ubaa8\ub974\ub294 \ubd80\ubd84\uc774 \uc5ec\uc804\ud788 \ub0a8\uc544 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc900\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4. \uae30\ucd08\uacfc\ud559\uc5f0\uad6c\uc6d0 \uc720\uc804\uccb4\ud56d\uc0c1\uc131\uc5f0\uad6c\ub2e8\uc758 \uc784\ud0dc\uc9c4 \uc5f0\uad6c\uc704\uc6d0\uc740 \u201c\ub300\ubd80\ubd84 \uc720\uc804\uc790\uac00\uc704 \uc5f0\uad6c\uac00 \ud65c\uc6a9\uacfc \uad00\ub828\ub418\uc5b4 \uc774\ub904\uc9c0\uace0 \uc788\uace0 \ub514\uc5d4\uc5d0\uc774 \ubcf5\uad6c \uacfc\uc815\uc758 \uae30\ucd08 \uc5f0\uad6c\ub294 \uc18c\uc218 \uadf8\ub8f9\uc5d0\uc11c \uc9c4\ud589\ub418\ub294 \uac83\uc73c\ub85c \uc54c\uace0 \uc788\ub2e4\u201d\uace0 \uc804\ud588\ub2e4.<\/p>\n<p>\ub110\ub9ac \uc54c\ub824\uc9c4 \ub514\uc5d4\uc5d0\uc774 \ubcf5\uad6c \ubc29\uc2dd\uc740 \ub300\uccb4\ub85c \ub450 \uac00\uc9c0\ub85c \uad6c\ubd84\ub41c\ub2e4(<b>\uadf8\ub9bc<\/b>\u00a0\ucc38\uc870). \ud754\ud55c \uac83\uc740 \ub04a\uc5b4\uc9c4 \ub514\uc5d4\uc5d0\uc774 \ub450 \uac00\ub2e5\uc758 \ub9d0\ub2e8 \uc9c0\uc810\uc744 \uc774\uc5b4\ubd99\uc774\ub294 \ubc29\uc2dd(\ube44\uc0c1\ub3d9 \ub9d0\ub2e8\uc5f0\uacb0,\u00a0<span class=\"word_dic en\">NHEJ<\/span>)\uc774\ub2e4. \uc591 \ub05d\uc744 \ub2e4\ub4ec\uace0 \ubd99\uc774\ub294 \uacfc\uc815\uc5d0\uc11c \ud06c\uace0 \uc791\uc740 \uaddc\ubaa8\ub85c \uc5fc\uae30\uc11c\uc5f4\uc774 \ub5a8\uc5b4\uc838 \ub098\uac00\uac70\ub098, \ub07c\uc5b4\ub4e4\uac70\ub098, \uc5fc\uae30\uc11c\uc5f4 \uc7ac\ubc30\uc5f4\uc774 \uc77c\uc5b4\ub098\uae30\ub3c4 \ud55c\ub2e4. \uc720\uc804\uc790\uac00\uc704\ub294 \uc138\ud3ec\uc758 \uc774\ub7f0 \ubcf5\uad6c \ubc29\uc2dd\uc744 \ud65c\uc6a9\ud574 \uc720\uc804\uc790\uc5d0\ub2e4 \uc77c\ubd80\ub7ec \ubcc0\uc774\ub97c \uc77c\uc73c\ud0b4\uc73c\ub85c\uc368 \uc9c8\ubcd1 \uad00\ub828 \uc720\uc804\uc790\uc758 \uae30\ub2a5\uc744 \uc5c6\uc568 \uc218 \uc788\ub2e4.<\/p>\n<p>\ub2e4\ub978 \ubc29\uc2dd\uc740 \ub2e4\ub978 \uacf3\uc5d0\ub3c4 \ubcf4\uad00\ub41c \uac19\uc740 \uc5fc\uae30\uc11c\uc5f4 \uc815\ubcf4\ub97c \ucc3e\uc544\ub0b4\uc5b4 \uadf8\uac83\uc744 \uc8fc\ud615(\ud2c0)\uc73c\ub85c \uc0bc\uc544 \uc5fc\uae30\uc11c\uc5f4\uc744 \ubcf5\uc6d0\ud558\ub294 \ubc29\uc2dd\uc774\ub2e4. \u2018\uc0c1\ub3d9 \uc5fc\uc0c9\uccb4\u2019\uc5d0 \uc788\ub294 \uc815\ubcf4\ub97c \uac00\uc838\uc640 \ub04a\uc5b4\uc9c4 \ub514\uc5d4\uc5d0\uc774 \ubd80\uc704\uc758 \ubcf5\uad6c\uc5d0 \ud65c\uc6a9\ud55c\ub2e4(\uc0c1\ub3d9 \uc7ac\uc870\ud569 \ubcf5\uad6c\u00a0<span class=\"word_dic en\">HDR<\/span>). \uc5f0\uad6c\uc790\uac00 \ubbf8\ub9ac \uc124\uacc4\ud55c \ub514\uc5d4\uc5d0\uc774 \uc870\uac01\uc744 \uc720\uc804\uc790\uac00\uc704 \ubd84\uc790\uc640 \ud568\uaed8 \uc138\ud3ec\uc5d0 \ub123\uc73c\uba74, \uc720\uc804\uc790\uac00\uc704\uac00 \ub514\uc5d4\uc5d0\uc774 \ud45c\uc801\uc9c0\uc810\uc744 \uc808\ub2e8\ud560 \ub54c \uc138\ud3ec\ub294 \uc81c\uacf5\ub41c \ub514\uc5d4\uc5d0\uc774 \uc870\uac01\uc744 \uc8fc\ud615\uc73c\ub85c \uc0bc\uc544 \uc5f0\uad6c\uc790\uc758 \uc758\ub3c4\ub300\ub85c \ub514\uc5d4\uc5d0\uc774\ub97c \uc7ac\uac74\ud55c\ub2e4. \uadf8\ub7ec\uba74 \ubbf8\ub9ac \uc124\uacc4\ud55c \ub514\uc5d4\uc5d0\uc774 \uc870\uac01\uc774 \ubcf8\ub798 \ub514\uc5d4\uc5d0\uc774\uc758 \uc790\ub9ac\ub97c \ub300\uc2e0 \ucc28\uc9c0\ud55c\ub2e4.<\/p>\n<p>\uc774\ucc98\ub7fc \uc720\uc804\uc790\uac00\uc704 \uae30\uc220\uc740 \uc138\ud3ec\uc758 \ub450 \uac00\uc9c0 \ub514\uc5d4\uc5d0\uc774 \ubcf5\uad6c \ubc29\uc2dd\uc744 \uc801\uc808\ud788 \ud65c\uc6a9\ud574, \ud2b9\uc815 \uc720\uc804\uc790 \uae30\ub2a5\uc744 \uc815\uc9c0\uc2dc\ud0ac \uc218\ub3c4 \uc788\uace0 \ud2b9\uc815 \ub514\uc5d4\uc5d0\uc774 \uc870\uac01\uc744 \ub123\uc5b4 \uc720\uc804\uc790 \ud615\uc9c8\uc744 \ubc14\uafc0 \uc218\ub3c4 \uc788\ub2e4.<\/p>\n<p>\uadf8\ub7f0\ub370 \ucd5c\uadfc \uc548\uc804\uc131 \uc5f0\uad6c\ub4e4\uc740 \uc720\uc804\uc790\uac00\uc704\uc758 \ub514\uc5d4\uc5d0\uc774 \uc808\ub2e8 \uc774\ud6c4\uc5d0 \uc77c\uc5b4\ub098\ub294 \uc138\ud3ec\uc758 \ub300\uc751\uc774 \uc0dd\uac01\ubcf4\ub2e4 \ubcf5\uc7a1\ud568\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uac83\uc73c\ub85c\ub3c4 \ud480\uc774\ub41c\ub2e4. \uc138\ud3ec\uc5d0\uc120 p53 \uac19\uc740 \uc720\uc804\uc790\uac00 \ub098\uc11c\uc11c \uc720\uc804\uc790\uac00\uc704\uc758 \uc791\ub3d9\uc744 \ubc29\ud574 \ub610\ub294 \uc800\ud56d\ud558\ub294 \uc2dc\uc2a4\ud15c\uc744 \uac00\ub3d9\ud558\uba70, \uc720\uc804\uc790\uac00\uc704\uac00 \ud45c\uc801\uc9c0\uc810\uc744 \uc790\ub974\ub354\ub77c\ub3c4 \ubcf5\uad6c \uacfc\uc815\uc5d0\uc11c \uadf8 \uc601\ud5a5\uc774 \uc0c1\ub2f9\ud55c \uc815\ub3c4\ub85c \ub098\ud0c0\ub0a8\uc744 \ubcf4\uc5ec\uc900\ub2e4. \uae40\uc9c4\uc218 \ub2e8\uc7a5\uc740 \u201c\uc5b4\ub5a4 \uacbd\ub85c\ub85c \uc5b4\ub5a4 \ub2e8\ubc31\uc9c8\uc5d0 \uc758\ud574 \uc774\ub7f0 \ud45c\uc801\uc9c0\uc810 \ubcc0\uc774\uac00 \ubc1c\uc0dd\ud558\ub294 \uac83\uc778\uc9c0\uac00 \uaddc\uba85\ub418\uc5b4\uc57c \ud558\ub2e4\u201d\uba74\uc11c \u201c\uba54\ucee4\ub2c8\uc998\uc744 \uc774\ud574\ud558\uba74 [\ubcc0\uc774 \uc720\ubc1c\uc744] \uc81c\uc5b4\ud560 \uc218 \uc788\uc744 \uac83\u201d\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<p><b>\uc548\uc804\uc131 \ubb38\uc81c\ud480\uc774 \uc5f0\uad6c\ub3c4 \ud65c\ubc1c<\/b><\/p>\n<p>\ubc30\uc0c1\uc218 \ud55c\uc591\ub300 \uad50\uc218\ub294 \u201c\uc81c\uae30\ub418\ub294 \uc5ec\ub7ec \uc548\uc804\uc131 \ubb38\uc81c\ub4e4\uc774 \uadf9\ubcf5 \ubd88\uac00\ub2a5\ud55c \uac83\uc740 \uc544\ub2c8\ub2e4\u201d\uba74\uc11c \u201c\ubb38\uc81c\ub4e4\uc744 \uadf9\ubcf5\ud558\uac70\ub098 \uc6b0\ud68c\ud560 \uc218 \uc788\ub294 \uc5ec\ub7ec \uc5f0\uad6c\uac00 \ub098\uc624\uace0 \uc788\uace0 \ub610\ud55c \ub098\uc62c \uac83\u201d\uc774\ub77c\uace0 \ub099\uad00\ud588\ub2e4.<\/p>\n<p>\uc720\uc804\uc790\uac00\uc704\uac00 \ud45c\uc801\uc744 \ubc97\uc5b4\ub09c \uacf3\uc5d0\ub2e4 \uc758\ub3c4\ud558\uc9c0 \uc54a\uc740 \uc808\ub2e8\uacfc \ubcc0\uc774 \ud6a8\uacfc\ub97c \uc77c\uc73c\ud0ac \uc218 \uc788\ub2e4\ub294 \u2018\ud45c\uc801\uc774\ud0c8\u2019 \ubb38\uc81c\uac00 \uc81c\uae30\ub41c \uc774\ud6c4\uc5d0 \uc774\ub97c \uadf9\ubcf5\ud558\uac70\ub098 \uc6b0\ud68c\ud558\ub294 \uc5f0\uad6c\uac1c\ubc1c\uc774 \uad6d\ub0b4\uc678 \uc5ec\ub7ec \uc5f0\uad6c\uc9c4\uc5d0 \uc758\ud574 \uc774\ub904\uc84c\ub4ef\uc774, \uc0c8\ub85c\uc6b4 \uc548\uc804\uc131 \ubb38\uc81c\uc5d0 \ub300\ud574\uc11c\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\ub85c \ubb38\uc81c \ud480\uc774 \uc5f0\uad6c\ub4e4\uc774 \uc774\ub904\uc9c8 \uac83\uc73c\ub85c \ub0b4\ub2e4\ubcf4\uace0 \uc788\ub2e4. \uc774\ubbf8 \ub514\uc5d4\uc5d0\uc774\ub97c \uc790\ub974\uc9c0 \uc54a\uc740 \ucc44 \uc5fc\uae30 \ud558\ub098\ub9cc\uc744 \uad50\uccb4\ud558\ub294 \uc720\uc804\uc790\uac00\uc704\uc758\u00a0\u2018\uc5fc\uae30\ud3b8\uc9d1\u2019 \uae30\ubc95\ub3c4 \ub4f1\uc7a5\ud574\u00a0\ube60\ub974\uac8c \ubc1c\uc804\ud558\uace0 \uc788\ub2e4(\ud55c\uaca8\ub808 2017\ub144 11\uc6d46\uc77c\uce58 17\uba74).<\/p>\n<p>\ubbf8\uad6d \ud53c\uce20\ubc84\uadf8\ub300\ud559\uc758 \uc9c0\uc548\ud6c4\uc544 \ub8e8\uc624 \uad50\uc218\ub294 \ud574\uc678\ub9e4\uccb4\u00a0&lt;\ub354 \ucee8\ubc84\uc138\uc774\uc158&gt;\uc5d0 \uae30\uace0\ud55c \uae00\uc5d0\uc11c \u201c\ucd5c\uadfc \uc548\uc804\uc131 \uc5f0\uad6c\ub4e4\uc740 \uce58\ub8cc\ubc95 \uac1c\ubc1c\uc5d0\uc11c \uace0\ub824\ud574\uc57c \ud558\ub294 \uc720\uc804\uc790\uac00\uc704\uc758 \uc791\ub3d9\ubc29\uc2dd\uc5d0 \uad00\ud574 \uc0c8\ub85c\uc6b4 \uce21\uba74\uc744 \ubc1d\ud600\uc8fc\uace0 \uc788\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4. \uae40\ud615\ubc94 \uc5f0\uc138\ub300 \uc758\ub300 \uad50\uc218\ub294 \u201c\ubd80\uc791\uc6a9\uc774 \uc804\ud600 \uc5c6\ub294 \uce58\ub8cc\ubc95\uc740 \uc0ac\uc2e4 \uac70\uc758 \uc5c6\ub2e4\u201d\uba74\uc11c \u201c\uc548\uc804\uc131 \ubb38\uc81c\ub4e4\uc744 \uc904\uc774\ub294 \ubc29\ubc95\uc774 \uc774\ubbf8 \uc81c\uc2dc\ub418\uac70\ub098 \uc5f0\uad6c\ub418\uace0 \uc788\uc5b4 \uc7a5\uae30\uc801\uc73c\ub85c \uc704\ud5d8\uc740 \uc904\uace0 \ud61c\ud0dd\uc740 \ub298 \uac83\uc73c\ub85c \uae30\ub300\ud55c\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4. \uc720\uc804\uc790\uac00\uc704\uc758 \uc791\ub3d9 \uc6d0\ub9ac\ub97c \uc5f0\uad6c\ud574\uc628 \uae40\uc131\uadfc \uc11c\uc6b8\ub300 \uad50\uc218(\ud654\ud559)\ub294 \u201c\uacfc\ud559\uc790\uc758 \uc9c0\ub098\uce5c \ub099\uad00\uc8fc\uc758\uc640 \ub300\uc911\ub9e4\uccb4\uc758 \uc120\uc815\uc801 \ubcf4\ub3c4\uac00 \uacb0\ud569\ud558\uba74 \uc131\uae09\ud55c \ud76c\ub9dd\uacfc \uc5ec\ub7ec \uc0ac\ud68c\uc801 \ubd80\uc791\uc6a9\uc744 \ub0b3\uc744 \uc218 \uc788\ub2e4\u201d\uba74\uc11c \uc720\uc804\uc790\uac00\uc704 \uc2e0\uae30\uc220\uc744 \ub420\uc218\ub85d \ud604\uc2e4\uc801\uc778 \ub208\uc73c\ub85c \ubc14\ub77c\ubcf4\ub824\uace0 \ub178\ub825\ud574\uc57c \ud55c\ub2e4\uace0 \uc8fc\ubb38\ud588\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; (\uc6d0\ubb38) &nbsp; &nbsp; \uc720\uc804\uc790\uce58\ub8cc \uc548\uc804\uc131 \uc5f0\uad6c \uc5b4\ub514\uae4c\uc9c0 \uc720\uc804\uc790\uac00\uc704, \uc815\ud655\ud788 \ud45c\uc801 \uc798\ub77c\ub3c4 DNA\u00a0\uacb0\uc2e4\u00b7\uc0bd\uc785\u00b7\uc7ac\ubc30\uc5f4 \ubd80\uc791\uc6a9 \ubcc0\uc774\uc720\ubc1c \uba54\ucee4\ub2c8\uc998 \uaddc\uba85 \uc0c8 \uacfc\uc81c \uac00\uc704 \uc791\ub3d9 \uc774\ud6c4 \uc138\ud3ec \ub300\uc751<a href=\"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1347\" 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Biology!","link":"https:\/\/biochemistry.khu.ac.kr\/lab\/?cat=33"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1589,"url":"https:\/\/biochemistry.khu.ac.kr\/lab\/?p=1589","url_meta":{"origin":1347,"position":4},"title":"\ud06c\ub9ac\uc2a4\ud37c \uac00\uc704\ub85c \uc720\uc804\uc790 \uc870\uc791\ud55c \uc0dd\ubb3c, GMO\ub85c \uaddc\uc81c\ud574\uc57c \ud558\ub098","author":"biochemistry","date":"September 9, 2018","format":false,"excerpt":"\u00a0 \u00a0 (\uc6d0\ubb38) \u00a0 \u00a0 \uc9c0\ub09c 8\uc6d4 21\uc77c \ud55c\uad6d\uc0dd\uba85\uacf5\ud559\uc5f0\uad6c\uc6d0(\uc774\ud558 \uc0dd\uba85\uc5f0) \ubc14\uc774\uc624\uc548\uc804\uc131\uc815\ubcf4\uc13c\ud130\ub294 \u20182017 \uc720\uc804\uc790\ubcc0\ud615\uc0dd\ubb3c\uccb4 \uc8fc\uc694 \ud1b5\uacc4\u2019\ub97c \ubc1c\ud45c\ud588\ub2e4. \uc720\uc804\uc790\ubcc0\ud615 \uc0dd\ubb3c\uccb4(GMO,\u00a0Genetically\u00a0ModifiedOrganism)\ub294 \uc720\uc804\uc790 \uc7ac\uc870\ud569 \uae30\uc220\uc774 \uc801\uc6a9\ub41c 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